TTC28 and WEE2-AS1

Number of citations: 47 (PubMedID 36168628)
Data Source: BioGRID (unspecified method)

		TTC28	WEE2-AS1
Name		tetratricopeptide repeat domain 28	WEE2 antisense RNA 1
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Spindle Pole Cytoplasm Centrosome Spindle Cytoskeleton Midbody	U1 SnRNP
	Molecular Function	Kinase Binding	Pre-mRNA 5'-splice Site Binding
	Biological Process	Regulation Of Mitotic Cell Cycle Cell Division	MRNA 5'-splice Site Recognition
GWAS		Aspartate aminotransferase levels ( 33547301 ) Body mass index ( 28552196 ) Cerebrospinal fluid p-Tau181p:AB1-42 ratio ( 26252872 ) Cerebrospinal P-tau181p levels ( 26252872 ) Cerebrospinal T-tau levels ( 26252872 ) Chronotype ( 30696823 ) Cleft lip with or without cleft palate (maternal periconceptional vitamin use interaction) ( 29535761 ) Femur bone mineral density x serum urate levels interaction ( 34046847 ) Hemoglobin levels ( 32327693 ) Left-handedness ( 32989287 ) Lymphocyte count ( 27863252 32888494 ) Lymphocyte percentage of white cells ( 32888494 ) Multiple sclerosis ( 31604244 ) Pancreatic cancer ( 25086665 ) Plateletcrit ( 32888494 ) Polycystic ovary syndrome (adjusted for age and BMI) ( 34791234 ) Polycystic ovary syndrome (adjusted for age) ( 34791234 ) Prostate cancer ( 29892016 ) Red cell distribution width ( 32888494 ) Systolic blood pressure ( 30224653 ) Triglyceride levels ( 32203549 ) Vertical cup-disc ratio (multi-trait analysis) ( 31959993 ) White blood cell count ( 27863252 )	No GWAS studies recorded
Interacting Genes		5 interacting genes: HRAS HUNK SSPOP UBC WEE2-AS1	161 interacting genes: AASS ACSL3 ACTG1 AGAP1 AHNAK AJUBA AKAP11 ALB ALKBH4 ANXA2 ARL6IP4 ASPSCR1 ATAD3A BCLAF1 BRAT1 CALML5 CLPB COPB2 COPG1 CSTF1 CTNND1 CTU2 DAXX DDX1 DDX23 DIDO1 DLST DNAAF5 DOHH DPYSL4 DSC1 DSP EEF1A1 EGR2 EIF3A ELL EMD EPM2AIP1 ERAP1 ERH EXOC4 FAM120B FAM83H FLG FLG2 FMR1 FOXK1 FXR1 FXR2 GAB1 GAPDH GBF1 GNL3 GRB10 GSDME GSN GTF3C1 GTPBP1 GTSE1 HARS1 HAX1 HMGA1 HMGCS1 HNRNPA2B1 HNRNPC HNRNPH1 HNRNPH2 HNRNPLL HNRNPM HSP90AA1 HSP90AB1 HSPA6 HSPA8 HSPB1 IFIT1 IGF2BP1 IGF2BP3 KCTD3 KIF20A KIF22 LAMC1 LARP7 LDLR LUC7L2 MAGED2 MAP1A MED23 MINDY3 MOB1A MSH6 MYH9 MYO1C NCKAP1 NDFIP1 NEK9 NISCH NPM1 NUP160 NXF1 PABPC1 PALS2 PARP1 PCMT1 PDCD2L PDXP PIGU PJA2 PLEC POP1 PPL PPM1F PRKAR2A PSMB1 PSMD1 PTK2 QTRT2 RAB5A RAF1 RETREG2 RPL13 RPLP2 RPN2 RPP30 RPRD1B RPS17 RPS2 RPS28 RPS29 RPS8 S100A14 S100A7 SEC13 SERBP1 SHKBP1 SHTN1 SKIC2 SLC25A11 SLC27A3 SNX8 SQSTM1 SRP68 STAT5B TANK THBS1 THRAP3 TIMELESS TMPO TOR1AIP2 TPR TRIM21 TRIM56 TRMT10C TTC28 TUBA1B TUBB3 TUBB4B U2AF1 UBB USP1 XRCC6 YBX1
Entrez ID		23331	285962
HPRD ID		10020	08286
Ensembl ID		ENSG00000100154	ENSG00000228775
Uniprot IDs		Q96AY4	Not available
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		None	RNA Binding Cytosol Ribonucleoprotein Complex Cytoplasm Nucleus Focal Adhesion Extracellular Exosome Nucleobase-containing Compound Metabolic Process Macromolecule Metabolic Process Nucleic Acid Metabolic Process RNA Metabolic Process Regulation Of Protein Metabolic Process Cytoplasmic Stress Granule MRNA Binding N6-methyladenosine-containing RNA Reader Activity Protein Binding MRNA Processing RNA Transport Nucleolus MRNA Transport Biological_process RNA Processing Nucleic Acid Binding Cellular Response To Heat Translation Regulator Activity Positive Regulation Of Protein Metabolic Process Nucleoplasm Positive Regulation Of Metabolic Process Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Cornified Envelope Positive Regulation Of Macromolecule Metabolic Process MRNA Metabolic Process Positive Regulation Of Biosynthetic Process Response To Heat Regulation Of Translation Regulation Of MRNA Stability CRD-mediated MRNA Stabilization Ficolin-1-rich Granule Lumen MRNA 3'-UTR Binding Nucleobase-containing Compound Transport Regulation Of RNA Stability Negative Regulation Of MRNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Ubiquitin Protein Ligase Binding Structural Molecule Activity Positive Regulation Of Gene Expression RNA Splicing Cadherin Binding Negative Regulation Of MRNA Catabolic Process Regulation Of Plasma Membrane Organization