ANKRD28 and AGPAT2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ANKRD28	AGPAT2
Gene Name		ankyrin repeat domain 28	1-acylglycerol-3-phosphate O-acyltransferase 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding	1-acylglycerol-3-phosphate O-acyltransferase Activity
	Biological Process		Positive Regulation Of Cytokine Production Positive Regulation Of Cytokine-mediated Signaling Pathway Phospholipid Metabolic Process Phosphatidic Acid Biosynthetic Process Epidermis Development CDP-diacylglycerol Biosynthetic Process Triglyceride Biosynthetic Process Cellular Lipid Metabolic Process Small Molecule Metabolic Process Glycerophospholipid Biosynthetic Process
Pathways			Synthesis of PA Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Phospholipid metabolism Glycerophospholipid biosynthesis Triglyceride Biosynthesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: AGPAT2 CSNK2B TGM2 ZNF512B	6 interactors: ABCG8 ANKRD28 GMPS PHF11 PHRF1 SLC23A2
Entrez ID		23243	10555
HPRD ID		10651	04373
Ensembl ID		ENSG00000206560	ENSG00000169692
Uniprot IDs		O15084	O15120
PDB IDs
Enriched GO Terms of Interacting Partners?		Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Epithelium Development Positive Regulation Of Signal Transduction Salivary Gland Cavitation Positive Regulation Of Activin Receptor Signaling Pathway Positive Regulation Of Mitochondrial Calcium Ion Concentration Adiponectin-activated Signaling Pathway Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Tissue Development Endothelial Tube Morphogenesis Tube Morphogenesis CDP-diacylglycerol Biosynthetic Process CDP-diacylglycerol Metabolic Process Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G-protein Coupled Signaling Pathway Mitochondrial Calcium Ion Homeostasis Morphogenesis Of An Epithelium Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Activin Receptor Signaling Pathway Phosphatidic Acid Biosynthetic Process Phosphatidic Acid Metabolic Process Tissue Morphogenesis Positive Regulation Of Cytokine-mediated Signaling Pathway Positive Regulation Of Response To Cytokine Stimulus Branching Involved In Salivary Gland Morphogenesis Tube Development Apoptotic Cell Clearance Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Signal Transduction Negative Regulation Of Endothelial Cell Migration Blood Vessel Remodeling Salivary Gland Morphogenesis Triglyceride Biosynthetic Process Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Peptide Cross-linking Regulation Of Blood Vessel Endothelial Cell Migration Salivary Gland Development Regulation Of Signaling Negative Regulation Of Epithelial Cell Migration Regulation Of Pathway-restricted SMAD Protein Phosphorylation Positive Regulation Of Smooth Muscle Cell Proliferation Exocrine System Development Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Protein Complex Assembly	Negative Regulation Of Intestinal Phytosterol Absorption Negative Regulation Of Intestinal Cholesterol Absorption Transepithelial L-ascorbic Acid Transport Molecular Hydrogen Transport L-ascorbic Acid Transport GMP Biosynthetic Process Nucleobase Transport Intestinal Cholesterol Absorption GMP Metabolic Process Regulation Of Intestinal Cholesterol Absorption Negative Regulation Of Cholesterol Transport Lipid Digestion L-ascorbic Acid Metabolic Process Transepithelial Transport Purine Nucleobase Biosynthetic Process Organic Anion Transport Vitamin Transmembrane Transport Response To Drug Intestinal Absorption Negative Regulation Of Lipid Transport Nucleobase-containing Compound Metabolic Process Cholesterol Efflux Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Anion Transport Glutamine Metabolic Process Regulation Of Cholesterol Transport Small Molecule Metabolic Process Cellular Nitrogen Compound Metabolic Process Purine Nucleobase Metabolic Process Vitamin Transport Excretion Nitrogen Compound Metabolic Process Carbohydrate Transmembrane Transport Pigment Biosynthetic Process Sterol Transport Cholesterol Transport Purine Ribonucleoside Monophosphate Biosynthetic Process Cholesterol Homeostasis Sterol Homeostasis Carboxylic Acid Metabolic Process Water-soluble Vitamin Metabolic Process
Tagcloud ?		adc aldh1l1 bhlhe40 cggbp1 ctdspl ephb1 fbln2 fgd5 foxp1 gnai2 gorasp1 iqsec1 itga itga9 loc285205 loc285375 lrrc3b lrrn1 mitf nkiras1 noti rbsp3 rpl15 rpl32 thrb ttc21 ube2e2 vhl wnt7a	abhd5 anomaly atgl cgi ctgm dgat1 diverge enteropathy gk glycerol gpd1 hsl ichthyosis inborn jordan lipe lipodystrophy loosing lpin1 lpin2 majeed nlsd perilipin pnpla2 pseudohypertriglyceridemia rhabdomyolysis steatosis tgs vacuolated
Tagcloud (Difference) ?		adc aldh1l1 bhlhe40 cggbp1 ctdspl ephb1 fbln2 fgd5 foxp1 gnai2 gorasp1 iqsec1 itga itga9 loc285205 loc285375 lrrc3b lrrn1 mitf nkiras1 noti rbsp3 rpl15 rpl32 thrb ttc21 ube2e2 vhl wnt7a	abhd5 anomaly atgl cgi ctgm dgat1 diverge enteropathy gk glycerol gpd1 hsl ichthyosis inborn jordan lipe lipodystrophy loosing lpin1 lpin2 majeed nlsd perilipin pnpla2 pseudohypertriglyceridemia rhabdomyolysis steatosis tgs vacuolated
Tagcloud (Intersection) ?