ANKRD28 and CD164

Number of citations: 48 (PubMedID 23414517)
Data Source: BioGRID (two hybrid)

		ANKRD28	CD164
Name		ankyrin repeat domain 28	CD164 molecule
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Protein Serine/threonine Phosphatase Complex Lamellipodium Cell Projection	Extracellular Region Lysosome Lysosomal Membrane Endosome Plasma Membrane Endosome Membrane Membrane
	Molecular Function	Protein Binding Protein Phosphatase Regulator Activity	Protein Binding
	Biological Process	Positive Regulation Of Focal Adhesion Assembly	Immune Response Cell Adhesion Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Negative Regulation Of Cell Adhesion Signal Transduction Muscle Organ Development Hemopoiesis
Pathways		Telomere Extension By Telomerase COPII-mediated vesicle transport	None
GWAS		Apolipoprotein A1 levels ( 32203549 ) HDL cholesterol levels ( 32203549 ) Mean platelet volume ( 32888494 ) Platelet count ( 32888494 ) Platelet distribution width ( 27863252 32888494 ) Refractive error ( 32231278 )	Appendicular lean mass ( 33097823 ) Granulocyte percentage of myeloid white cells ( 27863252 ) Height ( 18391951 31562340 ) Lung cancer ( 28604730 ) Mean corpuscular hemoglobin ( 20139978 28017375 29403010 ) Mean corpuscular volume ( 19862010 29403010 28017375 20139978 ) Midgestational circulating levels of PCBs ( 28235828 ) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269 ) Red blood cell count ( 28017375 29403010 20139978 ) Red blood cell traits ( 23446634 ) White blood cell count (basophil) ( 29403010 )
Interacting Genes		34 interacting genes: ABCF2 AGPAT2 ANK2 ANKRD26 ANKRD50 BCL3 BRCA1 CCDC187 CD164 CSNK2B EEF1G EHMT2 EIF3D GADD45GIP1 HNRNPK HNRNPR INCA1 KCNV2 MYOM1 NOTCH2 NOTCH3 PIBF1 PTRH1 RNF11 TGM2 TGS1 THAP7 TMIE TNKS TNKS2 TTN UACA YTHDC1 ZNF512B	6 interacting genes: ANKRD28 GRB2 HOXA1 KRTAP10-3 NBPF19 NOTCH2NLA
Entrez ID		23243	8763
HPRD ID		10651	04523
Ensembl ID		ENSG00000206560	ENSG00000135535
Uniprot IDs		O15084	D6R9B4 Q04900
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		M Band Sex-chromosome Dosage Compensation Dosage Compensation By Inactivation Of X Chromosome Positive Regulation Of Telomere Capping Glomerular Capillary Formation Enzyme Binding Marginal Zone B Cell Differentiation Negative Regulation Of Macromolecule Metabolic Process Heterochromatin Formation Cellular Response To Cocaine Protein Localization To Chromosome, Telomeric Region Protein Auto-ADP-ribosylation Protein Kinase A Signaling NAD+-protein-glutamate ADP-ribosyltransferase Activity Random Inactivation Of X Chromosome NAD+-protein-aspartate ADP-ribosyltransferase Activity Negative Regulation Of Gene Expression, Epigenetic Regulation Of Telomere Capping C2H2 Zinc Finger Domain Binding Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation Negative Regulation Of Metabolic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Protein Kinase Regulator Activity Regulation Of MiRNA Transcription Negative Regulation Of Nucleobase-containing Compound Metabolic Process Protein Poly-ADP-ribosylation Negative Regulation Of Fatty Acid Biosynthetic Process Regulation Of MiRNA Metabolic Process Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT Peptidyl-threonine Phosphorylation NAD+-protein Mono-ADP-ribosyltransferase Activity Pericentriolar Material Positive Regulation Of Telomere Maintenance Via Telomerase Nucleus Positive Regulation Of Telomere Maintenance Via Telomere Lengthening NAD+ Poly-ADP-ribosyltransferase Activity Negative Regulation Of Receptor Signaling Pathway Via STAT Mature B Cell Differentiation Involved In Immune Response Protein Localization To T-tubule Nucleoplasm Bcl3-Bcl10 Complex Mature B Cell Differentiation Peptide Dopaminyltransferase Activity Histone Serotonyltransferase Activity Peptide Histaminyltransferase Activity Protein-glutamine Glutaminase Activity Peptide Noradrenalinyltransferase Activity Peptide Serotonyltransferase Activity Histone Dopaminyltransferase Activity Negative Regulation Of Telomere Maintenance Via Telomere Lengthening	Guanyl-nucleotide Exchange Factor Adaptor Activity Grb2-EGFR Complex Semicircular Canal Formation Abducens Nerve Formation Optokinetic Behavior