AGPAT2 and SLC23A2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		AGPAT2	SLC23A2
Gene Name		1-acylglycerol-3-phosphate O-acyltransferase 2	solute carrier family 23 (ascorbic acid transporter), member 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Basal Plasma Membrane Membrane Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane
	Molecular Function	1-acylglycerol-3-phosphate O-acyltransferase Activity	L-ascorbate:sodium Symporter Activity Sodium-dependent Multivitamin Transmembrane Transporter Activity Nucleobase Transmembrane Transporter Activity L-ascorbic Acid Transporter Activity Sodium-dependent L-ascorbate Transmembrane Transporter Activity
	Biological Process	Positive Regulation Of Cytokine Production Positive Regulation Of Cytokine-mediated Signaling Pathway Phospholipid Metabolic Process Phosphatidic Acid Biosynthetic Process Epidermis Development CDP-diacylglycerol Biosynthetic Process Triglyceride Biosynthetic Process Cellular Lipid Metabolic Process Small Molecule Metabolic Process Glycerophospholipid Biosynthetic Process	Nucleobase-containing Compound Metabolic Process Vitamin Metabolic Process Water-soluble Vitamin Metabolic Process Sodium Ion Transport Response To Oxidative Stress Nucleobase Transport L-ascorbic Acid Transport Molecular Hydrogen Transport L-ascorbic Acid Metabolic Process Vitamin Transmembrane Transport Small Molecule Metabolic Process Transepithelial L-ascorbic Acid Transport
Pathways		Synthesis of PA Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Phospholipid metabolism Glycerophospholipid biosynthesis Triglyceride Biosynthesis	Metabolism of vitamins and cofactors Defective CD320 causes methylmalonic aciduria Defective GIF causes intrinsic factor deficiency Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF Defective HLCS causes multiple carboxylase deficiency Defective MMAB causes methylmalonic aciduria type cblB Defective BTD causes biotidinase deficiency Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC Defective MTR causes methylmalonic aciduria and homocystinuria type cblG Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD Vitamin C (ascorbate) metabolism Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE Defective MMAA causes methylmalonic aciduria type cblA Defective CUBN causes hereditary megaloblastic anemia 1 Defective AMN causes hereditary megaloblastic anemia 1 Defective MUT causes methylmalonic aciduria mut type Metabolism of water-soluble vitamins and cofactors Defects in biotin (Btn) metabolism Defective TCN2 causes hereditary megaloblastic anemia Defects in cobalamin (B12) metabolism Defects in vitamin and cofactor metabolism
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: ABCG8 ANKRD28 GMPS PHF11 PHRF1 SLC23A2	2 interactors: AGPAT2 NEDD4
Entrez ID		10555	9962
HPRD ID		04373	04811
Ensembl ID		ENSG00000169692	ENSG00000089057
Uniprot IDs		O15120	B4DJZ1 Q9UGH3
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Intestinal Phytosterol Absorption Negative Regulation Of Intestinal Cholesterol Absorption Transepithelial L-ascorbic Acid Transport Molecular Hydrogen Transport L-ascorbic Acid Transport GMP Biosynthetic Process Nucleobase Transport Intestinal Cholesterol Absorption GMP Metabolic Process Regulation Of Intestinal Cholesterol Absorption Negative Regulation Of Cholesterol Transport Lipid Digestion L-ascorbic Acid Metabolic Process Transepithelial Transport Purine Nucleobase Biosynthetic Process Organic Anion Transport Vitamin Transmembrane Transport Response To Drug Intestinal Absorption Negative Regulation Of Lipid Transport Nucleobase-containing Compound Metabolic Process Cholesterol Efflux Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Anion Transport Glutamine Metabolic Process Regulation Of Cholesterol Transport Small Molecule Metabolic Process Cellular Nitrogen Compound Metabolic Process Purine Nucleobase Metabolic Process Vitamin Transport Excretion Nitrogen Compound Metabolic Process Carbohydrate Transmembrane Transport Pigment Biosynthetic Process Sterol Transport Cholesterol Transport Purine Ribonucleoside Monophosphate Biosynthetic Process Cholesterol Homeostasis Sterol Homeostasis Carboxylic Acid Metabolic Process Water-soluble Vitamin Metabolic Process	Transmission Of Virus Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Development Involved In Symbiotic Interaction Progesterone Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Glucocorticoid Receptor Signaling Pathway Protein Targeting To Lysosome CDP-diacylglycerol Biosynthetic Process Negative Regulation Of Sodium Ion Transport CDP-diacylglycerol Metabolic Process Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Protein Localization To Lysosome Receptor Catabolic Process Protein Targeting To Vacuole Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Establishment Of Protein Localization To Vacuole Phosphatidic Acid Biosynthetic Process Phosphatidic Acid Metabolic Process Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Cytokine-mediated Signaling Pathway Positive Regulation Of Response To Cytokine Stimulus Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Protein K63-linked Ubiquitination Positive Regulation Of Signal Transduction Endocardial Cushion Development Regulation Of Potassium Ion Transmembrane Transport Protein Monoubiquitination Receptor Internalization Triglyceride Biosynthetic Process Lysosomal Transport Neuromuscular Junction Development Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Cellular Response To UV Regulation Of Potassium Ion Transport Outflow Tract Morphogenesis Tissue Development Regulation Of Sodium Ion Transport Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Dendrite Morphogenesis Intracellular Steroid Hormone Receptor Signaling Pathway Vacuolar Transport Receptor Metabolic Process Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Synapse Organization Regulation Of Synapse Structure Or Activity Cellular Response To Light Stimulus Triglyceride Metabolic Process Negative Regulation Of Ion Transport
Tagcloud ?		abhd5 anomaly atgl cgi ctgm dgat1 diverge enteropathy gk glycerol gpd1 hsl ichthyosis inborn jordan lipe lipodystrophy loosing lpin1 lpin2 majeed nlsd perilipin pnpla2 pseudohypertriglyceridemia rhabdomyolysis steatosis tgs vacuolated
Tagcloud (Difference) ?		abhd5 anomaly atgl cgi ctgm dgat1 diverge enteropathy gk glycerol gpd1 hsl ichthyosis inborn jordan lipe lipodystrophy loosing lpin1 lpin2 majeed nlsd perilipin pnpla2 pseudohypertriglyceridemia rhabdomyolysis steatosis tgs vacuolated
Tagcloud (Intersection) ?