AGPAT2 and SLC23A2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		AGPAT2	SLC23A2
Description		1-acylglycerol-3-phosphate O-acyltransferase 2	solute carrier family 23 member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Specific Granule Membrane	Cytoplasm Plasma Membrane Basal Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane
	Molecular Function	1-acylglycerol-3-phosphate O-acyltransferase Activity Transferase Activity Acyltransferase Activity	Protein Binding L-ascorbate:sodium Symporter Activity L-ascorbic Acid Transmembrane Transporter Activity Symporter Activity Transmembrane Transporter Activity
	Biological Process	Positive Regulation Of Cytokine Production Positive Regulation Of Cytokine-mediated Signaling Pathway Lipid Metabolic Process Phospholipid Metabolic Process Phosphatidic Acid Biosynthetic Process Epidermis Development Phospholipid Biosynthetic Process Response To Xenobiotic Stimulus CDP-diacylglycerol Biosynthetic Process Triglyceride Biosynthetic Process	Monoatomic Ion Transport Sodium Ion Transport Response To Oxidative Stress Cell Adhesion Blood Circulation L-ascorbic Acid Transmembrane Transport L-ascorbic Acid Metabolic Process Transmembrane Transport Cellular Response To Ethanol Positive Regulation Of Dendrite Extension
Pathways		Synthesis of PA Neutrophil degranulation MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis	Vitamin C (ascorbate) metabolism
Drugs
Diseases		Congenital generalized lipodystrophy (CGL)
GWAS			Femur bone mineral density x serum urate levels interaction ( 34046847) Height ( 28552196) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Red cell distribution width ( 32888494)
Interacting Genes		6 interacting genes: ABCG8 ANKRD28 GMPS PHF11 PHRF1 SLC23A2	9 interacting genes: AGPAT2 C3orf52 ERMP1 JAGN1 NEDD4 NSG1 SLC38A7 SLC41A1 TMEM60
Entrez ID		10555	9962
HPRD ID		04373	04811
Ensembl ID		ENSG00000169692	ENSG00000089057
Uniprot IDs		A0A024R8F9 O15120	A0A140VK48 Q9UGH3
PDB IDs
Enriched GO Terms of Interacting Partners?		GMP Synthase (glutamine-hydrolyzing) Activity GMP Synthase Activity L-ascorbic Acid Transmembrane Transport L-ascorbic Acid Transmembrane Transporter Activity L-ascorbate:sodium Symporter Activity Negative Regulation Of Intestinal Cholesterol Absorption Negative Regulation Of Intestinal Phytosterol Absorption Negative Regulation Of Intestinal Absorption ATP-binding Cassette (ABC) Transporter Complex Purine Nucleobase Biosynthetic Process L-ascorbic Acid Metabolic Process Protein Serine/threonine Phosphatase Complex Intestinal Cholesterol Absorption Regulation Of Intestinal Cholesterol Absorption Regulation Of Intestinal Lipid Absorption Intestinal Lipid Absorption Regulation Of Intestinal Absorption GMP Biosynthetic Process Purine Nucleobase Metabolic Process Purine Ribonucleoside Monophosphate Biosynthetic Process Cellular Response To Ethanol Apical Plasma Membrane Positive Regulation Of Dendrite Extension Vitamin Transmembrane Transport RNA Polymerase Binding	Ionotropic Glutamate Receptor Binding Sodium Ion Transport Receptor Metabolic Process Membrane Formation Of Structure Involved In A Symbiotic Process Endoplasmic Reticulum Postsynaptic Neurotransmitter Receptor Cycle Neurotransmitter Receptor Cycle L-asparagine:sodium Symporter Activity L-glutamine:sodium Symporter Activity Channel Inhibitor Activity Spontaneous Synaptic Transmission Magnesium:sodium Antiporter Activity Phosphothreonine Residue Binding Endoplasmic Reticulum Membrane Asparagine Transport L-asparagine Transmembrane Transporter Activity
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