EXOC6B and RALA

Number of citations of the paper that reports this interaction (PubMedID 11406615)
0

Data Source:
HPRD (in vitro)

		EXOC6B	RALA
Description		exocyst complex component 6B	RAS like proto-oncogene A
Image		No pdb structure
GO Annotations	Cellular Component	Exocyst Plasma Membrane	Mitochondrion Plasma Membrane Focal Adhesion Cell Surface Membrane Endocytic Vesicle Cytoplasmic Vesicle Membrane Cleavage Furrow Extracellular Exosome Flemming Body Synaptic Membrane Schaffer Collateral - CA1 Synapse
	Molecular Function	Protein Binding	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity Myosin Binding GDP Binding Ubiquitin Protein Ligase Binding Edg-2 Lysophosphatidic Acid Receptor Binding ATPase Binding
	Biological Process	Mitotic Cytokinesis Intracellular Protein Transport Exocytosis Golgi To Plasma Membrane Transport Vesicle Docking Involved In Exocytosis Protein Transport Membrane Fission Vesicle Tethering Involved In Exocytosis	Neural Tube Closure Exocytosis Chemotaxis Signal Transduction Ras Protein Signal Transduction Regulation Of Exocytosis Receptor Internalization Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Cell Division Positive Regulation Of Filopodium Assembly Membrane Raft Localization Establishment Of Protein Localization To Mitochondrion Positive Regulation Of Mitochondrial Fission Regulation Of Postsynaptic Neurotransmitter Receptor Internalization
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane p38MAPK events Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs			Guanosine-5'-Diphosphate
Diseases
GWAS		Appendicular lean mass ( 33097823) Diastolic blood pressure ( 27841878 30224653) Height ( 31562340) Malaria ( 31844061) Serum metabolite levels ( 33031748) Severe autoimmune type 2 diabetes ( 34737425) Systolic blood pressure ( 27841878)
Interacting Genes		3 interacting genes: MTERF1 RALA SHTN1	31 interacting genes: ARF1 CALM1 CNKSR2 CTCF EXOC1 EXOC2 EXOC3 EXOC4 EXOC5 EXOC6B EXOC7 EXOC8 FLNA GLS2 HSPB1 LSM2 PIH1D2 PLCD1 PLD1 PPP2R1B RAB34 RAB8B RALBP1 RALGPS1 RASSF5 REPS1 RGL2 RGL4 SMAD4 SNCA YBX3
Entrez ID		23233	5898
HPRD ID		19418	01549
Ensembl ID		ENSG00000144036	ENSG00000006451
Uniprot IDs		A0A0U1RRB6 Q9Y2D4	P11233
PDB IDs			1UAD 1ZC3 1ZC4 2A78 2A9K 2BOV 6P0I 6P0J 6P0K 6P0L 6P0M 6P0N 6P0O 7NQC 8FJH 8FJI
Enriched GO Terms of Interacting Partners?		Ras Protein Signal Transduction Glucosidase Activity Glc3Man9GlcNAc2 Oligosaccharide Glucosidase Activity Endoplasmic Reticulum Polarization Actin Filament Bundle Retrograde Transport Edg-2 Lysophosphatidic Acid Receptor Binding Termination Of Mitochondrial Transcription Cdc42 Protein Signal Transduction Intracellular Signaling Cassette NF-kappaB Complex Cytoplasmic Actin-based Contraction Involved In Cell Motility Small GTPase-mediated Signal Transduction Membrane Raft Localization DNA Geometric Change Netrin-activated Signaling Pathway	Vesicle Tethering Involved In Exocytosis Exocyst Vesicle Tethering Vesicle Docking Involved In Exocytosis Membrane Fission Organelle Localization By Membrane Tethering Membrane Docking Vesicle Docking Mitotic Cytokinesis Exocytosis Cytoskeleton-dependent Cytokinesis Golgi To Plasma Membrane Transport Vesicle-mediated Transport To The Plasma Membrane Secretion By Cell Organelle Localization Post-Golgi Vesicle-mediated Transport Vesicle-mediated Transport Small GTPase Binding Secretion Membrane Organization Intracellular Protein Localization Flemming Body Establishment Of Protein Localization Localization Within Membrane Protein Transport Perinuclear Region Of Cytoplasm Golgi Vesicle Transport Regulation Of Norepinephrine Uptake Regulation Of Ral Protein Signal Transduction Transporter Regulator Activity Ras Protein Signal Transduction Cellular Localization Intracellular Signaling Cassette Regulation Of Follicle-stimulating Hormone Secretion Positive Regulation Of Follicle-stimulating Hormone Secretion Cytoplasm Plasma Membrane Regulation Of Entry Of Bacterium Into Host Cell Negative Regulation Of Macrophage Differentiation Growth Cone Membrane Regulation Of Autophagy Platelet Aggregation Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Growth Cone Small GTPase-mediated Signal Transduction Positive Regulation Of Hormone Secretion Homotypic Cell-cell Adhesion Cytosol Positive Regulation Of Secretion By Cell Positive Regulation Of Secretion
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