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SWAP70 and IGHG1
Number of citations of the paper that reports this interaction (PMID
10681448
)
14
Data Source:
HPRD
(in vitro)
SWAP70
IGHG1
Gene Name
SWAP switching B-cell complex 70kDa subunit
immunoglobulin heavy constant gamma 1 (G1m marker)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Plasma Membrane
Lamellipodium
Extracellular Region
Extracellular Space
Extracellular Vesicular Exosome
Blood Microparticle
Molecular Function
DNA Binding
Calcium Ion Binding
ATP Binding
Antigen Binding
Protein Binding
Biological Process
Isotype Switching
Complement Activation
Complement Activation, Classical Pathway
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Innate Immune Response
Pathways
Drugs
Diseases
GWAS
IgG levels (
23225573
)
Protein-Protein Interactions
5 interactors:
CELSR3
IGHG1
PARP1
RAPGEF4
ZBTB5
7 interactors:
CD40LG
FCGR3A
FCGR3B
IGKC
SWAP70
TRIM21
UCHL5
Entrez ID
23075
3500
HPRD ID
10378
11755
Ensembl ID
ENSG00000133789
Uniprot IDs
E7EMB1
Q9UH65
PDB IDs
2DN6
Enriched GO Terms of Interacting Partners
?
Immune Response
Immune System Process
Immunoglobulin Mediated Immune Response
B Cell Mediated Immunity
Isotype Switching
DNA Recombination
Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains
Somatic Recombination Of Immunoglobulin Gene Segments
Leukocyte Mediated Immunity
Adaptive Immune Response
Somatic Diversification Of Immunoglobulins
Immunoglobulin Production Involved In Immunoglobulin Mediated Immune Response
B Cell Activation Involved In Immune Response
Immunoglobulin Production
Defense Response
Response To Stimulus
Negative Regulation Of Protein Deubiquitination
Leukocyte Activation Involved In Immune Response
B Cell Activation
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Response To Stress
Positive Regulation Of Viral Entry Into Host Cell
Innate Immune Response
Regulation Of Immune Response
Immunoglobulin Secretion
Regulation Of Protein Deubiquitination
Phagocytosis
Fc Receptor Signaling Pathway
DNA Metabolic Process
Immune Response-activating Cell Surface Receptor Signaling Pathway
Positive Regulation Of Endothelial Cell Apoptotic Process
Regulation Of Immunoglobulin Secretion
Negative Regulation Of Viral Release From Host Cell
Positive Regulation Of Cytokine Production
Regulation Of Immune System Process
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Lymphocyte Activation
Regulation Of Viral Entry Into Host Cell
Negative Regulation Of Viral Transcription
Forebrain Morphogenesis
Regulation Of Viral Release From Host Cell
Lateral Ventricle Development
Protein Destabilization
Cell Surface Receptor Signaling Pathway
Immune Response-regulating Signaling Pathway
Leukocyte Activation
Regulation Of Cytokine Production
Protein Trimerization
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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