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TWF2
Gene Name
twinfilin actin-binding protein 2
Image
Gene Ontology Annotations
Cellular Component
Cytoplasm
Cytoskeleton
Myofibril
Lamellipodium
Filopodium
Growth Cone
Stereocilium
Perinuclear Region Of Cytoplasm
Extracellular Vesicular Exosome
Molecular Function
Actin Monomer Binding
Protein Kinase C Binding
ATP Binding
Phosphatidylinositol-4,5-bisphosphate Binding
Poly(A) RNA Binding
Biological Process
Positive Regulation Of Lamellipodium Assembly
Positive Regulation Of Neuron Projection Development
Cell Projection Organization
Negative Regulation Of Actin Filament Polymerization
Regulation Of Microvillus Length
Regulation Of Actin Cytoskeleton Organization
Sequestering Of Actin Monomers
Positive Regulation Of Axon Extension
Barbed-end Actin Filament Capping
Cellular Response To Retinoic Acid
Cellular Response To Growth Factor Stimulus
Pathways
Drugs
Diseases
GWAS
Bipolar disorder (
21926972
)
Protein-protein Interactions
6 interactors:
ARHGDIA
CHGB
FOXJ1
ILK
POT1
TERF2IP
Entrez ID
11344
HPRD ID
08464
Ensembl ID
ENSG00000247596
Uniprot IDs
Q6IBS0
PDB IDs
2VAC
2W0I
Enriched GO Terms of Interacting Partners
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Telomere Capping
Telomere Maintenance Via Telomerase
Negative Regulation Of Telomere Maintenance
Regulation Of Telomere Maintenance
RNA-dependent DNA Replication
Establishment Or Maintenance Of Apical/basal Cell Polarity
Telomere Maintenance Via Telomere Lengthening
Telomere Maintenance
Positive Regulation Of Catalytic Activity
Positive Regulation Of Axonogenesis
Negative Regulation Of Chromosome Organization
Regulation Of Intracellular Signal Transduction
Negative Regulation Of DNA Metabolic Process
Regulation Of Cell Adhesion
Kidney Morphogenesis
Positive Regulation Of DNA Strand Elongation
Positive Regulation Of Lung Ciliated Cell Differentiation
Central Tolerance Induction
Negative Regulation Of DNA Recombination At Telomere
Glomerular Parietal Epithelial Cell Development
Positive Regulation Of Central B Cell Tolerance Induction
Regulation Of Cellular Component Organization
Ureteric Bud Development
Mesonephric Tubule Development
Mesonephric Epithelium Development
Mesonephros Development
Negative Regulation Of Cellular Metabolic Process
Nephron Development
Positive Regulation Of B Cell Tolerance Induction
Negative Regulation Of Germinal Center Formation
Regulation Of Axonogenesis
Positive Regulation Of Cell Differentiation
Kidney Epithelium Development
Positive Regulation Of Cell Morphogenesis Involved In Differentiation
Regulation Of Catalytic Activity
Regulation Of Organelle Organization
Establishment Or Maintenance Of Cell Polarity
Glomerular Parietal Epithelial Cell Differentiation
Telomere Formation Via Telomerase
Negative Regulation Of Cell Migration
Regulation Of Chromosome Organization
Negative Regulation Of Cell Adhesion
Positive Regulation Of Hydrolase Activity
Negative Regulation Of Cell Motility
Regulation Of Signal Transduction
Positive Regulation Of Neuron Projection Development
Negative Regulation Of Cellular Component Movement
Protection From Non-homologous End Joining At Telomere
Negative Regulation Of Locomotion
Protein Localization To Chromosome, Telomeric Region
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