RALY and HNRNPC

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid)

		RALY	HNRNPC
Gene Name		RALY heterogeneous nuclear ribonucleoprotein	heterogeneous nuclear ribonucleoprotein C (C1/C2)
Image
Gene Ontology Annotations	Cellular Component	Nucleus Catalytic Step 2 Spliceosome	Nuclear Chromatin Nucleus Nucleoplasm Spliceosomal Complex Cytosol Membrane Protein Complex Extracellular Vesicular Exosome Catalytic Step 2 Spliceosome
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding Poly(A) RNA Binding	Nucleotide Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Poly(U) RNA Binding Nucleosomal DNA Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome	MRNA Splicing, Via Spliceosome Osteoblast Differentiation RNA Splicing Gene Expression ATP-dependent Chromatin Remodeling 3'-UTR-mediated MRNA Stabilization
Pathways			Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Breast cancer ( 22976474)	Bipolar disorder ( 21738484)
Protein-Protein Interactions		11 interactors: CELF1 HNRNPC HNRNPD HNRNPH1 HNRNPK KHDRBS1 PCBP1 PIK3CD QKI SPG7 WDR62	48 interactors: AP1M1 BARD1 BRCA1 BRCA2 BRIP1 BTRC CCDC85B CDKN2A CELF1 CSNK1A1 CSNK2A1 CSNK2A2 DHX9 EPS8 ERG FAS FXR2 GRB2 HNRNPD IL7R KHDRBS3 KPNA2 KPNA3 KPNA4 KRAS LMO2 LMO3 PALB2 PDGFB PHKB PIN1 PRKDC PTBP2 RAD51 RALY RALYL RBM41 SDCBP SF3B2 SMARCD1 SREK1 SRPK2 SUMO1 SUMO1P1 UBE2I YWHAQ ZFYVE26 ZNF581
Entrez ID		22913	3183
HPRD ID		11480	01243
Ensembl ID		ENSG00000125970	ENSG00000092199
Uniprot IDs		Q53GL6 Q9UKM9	P07910
PDB IDs		1WF1	1TXP 1WF2 3LN4
Enriched GO Terms of Interacting Partners?		MRNA Processing MRNA Metabolic Process RNA Processing RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Posttranscriptional Regulation Of Gene Expression Regulation Of MRNA Stability Regulation Of RNA Stability Regulation Of Translation RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Translation Nitrogen Compound Metabolic Process Positive Regulation Of RNA Export From Nucleus Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter 3'-UTR-mediated MRNA Destabilization Regulation Of RNA Splicing Mast Cell Differentiation Natural Killer Cell Chemotaxis B Cell Chemotaxis Spermatid Development Neutrophil Extravasation Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Mast Cell Chemotaxis Regulation Of Protein Metabolic Process Spermatid Differentiation Respiratory Burst Involved In Defense Response Regulation Of Gene Expression Circadian Regulation Of Translation MRNA Destabilization Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Positive Regulation Of Gene Expression T Cell Chemotaxis Regulation Of Low-density Lipoprotein Particle Clearance Positive Regulation Of Receptor Biosynthetic Process 3'-UTR-mediated MRNA Stabilization RNA Destabilization Germ Cell Development Respiratory Burst Regulation Of RNA Export From Nucleus Positive Regulation Of Translational Initiation Long-chain Fatty Acid Biosynthetic Process RNA Interference Regulation Of Receptor Biosynthetic Process Lymphocyte Chemotaxis	Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cell Cycle Process Nitrogen Compound Metabolic Process Double-strand Break Repair Via Homologous Recombination Recombinational Repair Cellular Response To Stimulus Cell Cycle Double-strand Break Repair Negative Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing RNA Splicing, Via Transesterification Reactions Cellular Metabolic Process Regulation Of Cell Cycle Cellular Response To Organic Substance MRNA Processing DNA Repair Cellular Response To Cytokine Stimulus Regulation Of Cellular Process Response To Stimulus Positive Regulation Of Signal Transduction Cellular Response To DNA Damage Stimulus Cellular Response To Stress DNA Metabolic Process Regulation Of Cell Cycle Process Negative Regulation Of Gene Expression DNA Recombination Response To Cytokine Regulation Of Protein Metabolic Process MRNA Metabolic Process Response To Organic Substance Regulation Of Cellular Component Organization Response To Ionizing Radiation Regulation Of Transcription, DNA-templated Regulation Of Cellular Protein Metabolic Process Developmental Process Positive Regulation Of Cellular Metabolic Process NLS-bearing Protein Import Into Nucleus RNA Processing Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Mitotic Cell Cycle
Tagcloud ?		asip avian birds buds chickens color document dorsoventral eif2b encompasses feather hair implying lethal mammals melanin patterning pigmentation places quail quails remarkable similarities skins slc24a5 universal ventral vertebrates yellow	17th 2d appreciation coordinately coupling d deep dihydroxyvitamin entitled epigenome exerts expanded extra fine hormones issue linking locations microrna ribonucleoprotein special splicing steroid transcriptionally tuning vdr vdre vitamin workshop
Tagcloud (Difference) ?		asip avian birds buds chickens color document dorsoventral eif2b encompasses feather hair implying lethal mammals melanin patterning pigmentation places quail quails remarkable similarities skins slc24a5 universal ventral vertebrates yellow	17th 2d appreciation coordinately coupling d deep dihydroxyvitamin entitled epigenome exerts expanded extra fine hormones issue linking locations microrna ribonucleoprotein special splicing steroid transcriptionally tuning vdr vdre vitamin workshop
Tagcloud (Intersection) ?