SACM1L and COPG1

Number of citations of the paper that reports this interaction (PMID 14527956)
27

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)
HPRD (in vivo)

		SACM1L	COPG1
Gene Name		SAC1 suppressor of actin mutations 1-like (yeast)	coatomer protein complex, subunit gamma 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Integral Component Of Endoplasmic Reticulum Membrane Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Selective Glutamate Receptor Complex	Golgi Membrane Cytosol COPI Vesicle Coat
	Molecular Function	Phosphatidylinositol-3-phosphatase Activity Protein Binding Phosphatase Activity Phosphatidylinositol Bisphosphate Phosphatase Activity Phosphatidylinositol-4-phosphate Phosphatase Activity	Structural Molecule Activity Protein Binding
	Biological Process	Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Biological_process Small Molecule Metabolic Process Phosphatidylinositol Dephosphorylation	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To ER COPI Coating Of Golgi Vesicle Establishment Of Golgi Localization Membrane Organization Organelle Transport Along Microtubule
Pathways		Synthesis of PIPs at the Golgi membrane Metabolism of lipids and lipoproteins Synthesis of PIPs at the ER membrane Phospholipid metabolism PI Metabolism	COPI Mediated Transport Golgi to ER Retrograde Transport
Drugs			S-(Dimethylarsenic)Cysteine
Diseases
GWAS		Response to antidepressant treatment ( 22041458)
Protein-Protein Interactions		4 interactors: COPA COPB2 COPG1 PRKCA	15 interactors: ARCN1 ARF1 COPB1 COPE COPG2 COPZ1 COPZ2 DRD1 H2AFX PPBP PTGES3 RHOQ SACM1L TAPBP TMED10
Entrez ID		22908	22820
HPRD ID		07587	09887
Ensembl ID		ENSG00000211456	ENSG00000181789
Uniprot IDs		B4DK71 Q9NTJ5	Q9Y678
PDB IDs			1R4X
Enriched GO Terms of Interacting Partners?		COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Golgi Vesicle Budding Vesicle Targeting, To, From Or Within Golgi Retrograde Vesicle-mediated Transport, Golgi To ER Localization Within Membrane Vesicle Targeting Membrane Budding Membrane Organization Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Golgi Vesicle Transport Establishment Of Organelle Localization Organelle Localization Positive Regulation Of Dense Core Granule Biogenesis Intracellular Protein Transport Histone H3-T6 Phosphorylation Organelle Organization Cellular Protein Localization Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Intracellular Transport Peptidyl-serine Autophosphorylation Establishment Of Golgi Localization Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Pancreatic Juice Secretion Desmosome Assembly Negative Regulation Of Glial Cell Apoptotic Process Negative Regulation Of Glucose Import Positive Regulation Of Macrophage Differentiation Protein Localization Desmosome Organization Establishment Of Localization In Cell Golgi Localization Regulation Of Platelet Aggregation Negative Regulation Of Glucose Transport Induction Of Positive Chemotaxis Positive Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Lipopolysaccharide-mediated Signaling Pathway Regulation Of Body Fluid Levels Negative Regulation Of Adenylate Cyclase Activity Negative Regulation Of Lyase Activity Cellular Localization Regulation Of Rhodopsin Mediated Signaling Pathway Negative Regulation Of CAMP Biosynthetic Process Activation Of Adenylate Cyclase Activity Regulation Of Cardiac Muscle Hypertrophy	Retrograde Vesicle-mediated Transport, Golgi To ER COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Golgi Vesicle Budding Vesicle Targeting, To, From Or Within Golgi Localization Within Membrane Vesicle Targeting Golgi Vesicle Transport Membrane Budding Vesicle-mediated Transport Establishment Of Localization In Cell Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Intracellular Transport Cellular Localization Establishment Of Organelle Localization Protein Transport Intra-Golgi Vesicle-mediated Transport Establishment Of Protein Localization Organelle Localization Protein Localization Intracellular Protein Transport Cellular Protein Localization Membrane Organization Transport Organelle Organization Long Term Synaptic Depression Cerebellar Purkinje Cell Layer Maturation Peptide Antigen Stabilization Negative Regulation Of Synaptic Transmission Glucose Transport Hexose Transport Sensitization ER To Golgi Vesicle-mediated Transport Habituation Cerebellum Maturation Adult Locomotory Behavior Phosphatidylinositol Biosynthetic Process Carbohydrate Transport Nonassociative Learning Chaperone Cofactor-dependent Protein Refolding Response To Alkaloid Operant Conditioning Conditioned Taste Aversion Positive Regulation Of Adenylate Cyclase Activity Involved In G-protein Coupled Receptor Signaling Pathway Regulation Of Adenylate Cyclase Activity Involved In G-protein Coupled Receptor Signaling Pathway Lipid Biosynthetic Process Adult Behavior Regulation Of Synaptic Plasticity
Tagcloud ?		4b adriamycin ataxia carboplatin coded ct cyclophosphamide desirable eif4b isoaspartate matr3 matrin meiotic microrchidia morc3 pbl pbls pcmtd2 pdcd10 personalised psmb1 rmnd5a runt runx2 subtraction telangiectasia tmem66 undesired znf644
Tagcloud (Difference) ?		4b adriamycin ataxia carboplatin coded ct cyclophosphamide desirable eif4b isoaspartate matr3 matrin meiotic microrchidia morc3 pbl pbls pcmtd2 pdcd10 personalised psmb1 rmnd5a runt runx2 subtraction telangiectasia tmem66 undesired znf644
Tagcloud (Intersection) ?