ALDOB and HIVEP1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ALDOB	HIVEP1
Gene Name		aldolase B, fructose-bisphosphate	human immunodeficiency virus type I enhancer binding protein 1
Image
Gene Ontology Annotations	Cellular Component	Microtubule Organizing Center Cytosol Centriolar Satellite Extracellular Vesicular Exosome	Nucleus Nucleoplasm Mitochondrion
	Molecular Function	Fructose-bisphosphate Aldolase Activity Protein Binding Cytoskeletal Protein Binding Identical Protein Binding ATPase Binding Fructose-1-phosphate Aldolase Activity Fructose Binding	DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Carbohydrate Metabolic Process Fructose Metabolic Process Fructose Catabolic Process Glucose Metabolic Process Gluconeogenesis Glycolytic Process NADH Oxidation Pathogenesis Fructose 1,6-bisphosphate Metabolic Process Positive Regulation Of ATPase Activity Small Molecule Metabolic Process Vacuolar Proton-transporting V-type ATPase Complex Assembly	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated
Pathways		Fructose catabolism Gluconeogenesis Glucose metabolism Myoclonic epilepsy of Lafora Glycogen storage diseases Glycolysis Metabolism of carbohydrates
Drugs
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 22001757)	Alcohol and nictotine co-dependence ( 22488850)
Protein-Protein Interactions		8 interactors: AGXT2 ALDOA APP ATP6V1E1 HIVEP1 HSPA8 MUC20 TXN2	35 interactors: ALDOB APH1A APTX ASGR1 ATXN1 ATXN1L BHLHE40 BNIP3 BRCA1 CACNA1A DNAJA1 EMG1 GAA GSDMB HPD HRSP12 HSPA1A IMMT MAGED1 MAPK14 MAPK8 MTMR3 NHLH1 NINJ1 NUCB1 PRKAR1A RAB1A SDCBP SERTAD1 SMAD3 SNX4 SOCS3 SOX10 STAT3 TMEM176A
Entrez ID		229	3096
HPRD ID		01972	01925
Ensembl ID		ENSG00000136872	ENSG00000095951
Uniprot IDs		P05062	P15822
PDB IDs		1QO5 1XDL 1XDM	1BBO 3ZNF 4ZNF
Enriched GO Terms of Interacting Partners?		Cellular Homeostasis Platelet Degranulation L-alanine Catabolic Process, By Transamination Negative Regulation Of Fibril Organization Secretion By Cell Homeostatic Process Synaptic Growth At Neuromuscular Junction Glycine Biosynthetic Process, By Transamination Of Glyoxylate Secretion Collateral Sprouting In Absence Of Injury Regulation Of Fibril Organization Glyoxylate Catabolic Process Transition Metal Ion Homeostasis Response To Wounding L-alanine Metabolic Process L-alanine Catabolic Process Fructose 1,6-bisphosphate Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Clathrin Coat Disassembly Platelet Activation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Hepatocyte Growth Factor Receptor Signaling Pathway Glyoxylate Metabolic Process Neuron Remodeling Protein Homooligomerization	Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Cell Death Regulation Of Cell Death Neurotrophin Signaling Pathway Regulation Of Signaling Regulation Of Metabolic Process Response To Abiotic Stimulus Negative Regulation Of Cellular Metabolic Process Regulation Of Apoptotic Process Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Apoptotic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Metabolic Process Negative Regulation Of Programmed Cell Death Apoptotic Signaling Pathway Cellular Response To Growth Factor Stimulus Response To Growth Factor Response To Stress Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Metabolic Process Response To External Stimulus Regulation Of Transcription From RNA Polymerase II Promoter Cellular Metabolic Process Positive Regulation Of Gene Expression Regulation Of Cellular Protein Metabolic Process Regulation Of Signal Transduction Growth Regulation Of Phosphorylation Glucose Metabolic Process Anatomical Structure Morphogenesis Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Cell Death Death Negative Regulation Of Signal Transduction Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Phosphorus Metabolic Process Positive Regulation Of Apoptotic Process Intracellular Signal Transduction Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Signaling Positive Regulation Of Cell Death Regulation Of Cellular Component Organization Negative Regulation Of Phosphorylation Hexose Metabolic Process Positive Regulation Of Organelle Organization
Tagcloud ?		aldolase ambp anchor anonymous backcross bikunin d4h9s3e d4nds4 d9s3 dehydratase galt hexabrachion homologues hsa9 hsa9q hxb ifa interspecific levulinate localizations mmu4 orm orosomucoid pax pax5 synteny typed tyrp	16q22 aboriginal cholestasis cirh1a cirhin cirip cirrhosis collaboration evolves focuses helped hopital indian justine mapped naic nations northwestern nucleolus portal quebec r565w researchers splice ste tex292 twelve varices wd40
Tagcloud (Difference) ?		aldolase ambp anchor anonymous backcross bikunin d4h9s3e d4nds4 d9s3 dehydratase galt hexabrachion homologues hsa9 hsa9q hxb ifa interspecific levulinate localizations mmu4 orm orosomucoid pax pax5 synteny typed tyrp	16q22 aboriginal cholestasis cirh1a cirhin cirip cirrhosis collaboration evolves focuses helped hopital indian justine mapped naic nations northwestern nucleolus portal quebec r565w researchers splice ste tex292 twelve varices wd40
Tagcloud (Intersection) ?