ALDOB and AGXT2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ALDOB	AGXT2
Gene Name		aldolase B, fructose-bisphosphate	alanine--glyoxylate aminotransferase 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Microtubule Organizing Center Cytosol Centriolar Satellite Extracellular Vesicular Exosome	Mitochondrion Mitochondrial Matrix
	Molecular Function	Fructose-bisphosphate Aldolase Activity Protein Binding Cytoskeletal Protein Binding Identical Protein Binding ATPase Binding Fructose-1-phosphate Aldolase Activity Fructose Binding	Alanine-glyoxylate Transaminase Activity Beta-alanine-pyruvate Transaminase Activity Pyridoxal Phosphate Binding (R)-3-amino-2-methylpropionate-pyruvate Transaminase Activity
	Biological Process	Carbohydrate Metabolic Process Fructose Metabolic Process Fructose Catabolic Process Glucose Metabolic Process Gluconeogenesis Glycolytic Process NADH Oxidation Pathogenesis Fructose 1,6-bisphosphate Metabolic Process Positive Regulation Of ATPase Activity Small Molecule Metabolic Process Vacuolar Proton-transporting V-type ATPase Complex Assembly	Pyrimidine Nucleobase Metabolic Process Glyoxylate Catabolic Process Glycine Biosynthetic Process, By Transamination Of Glyoxylate L-alanine Catabolic Process, By Transamination Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Pyrimidine Nucleoside Catabolic Process Glyoxylate Metabolic Process Nucleobase-containing Small Molecule Metabolic Process
Pathways		Fructose catabolism Gluconeogenesis Glucose metabolism Myoclonic epilepsy of Lafora Glycogen storage diseases Glycolysis Metabolism of carbohydrates	Pyrimidine catabolism Glyoxylate metabolism Pyrimidine metabolism Metabolism of nucleotides Metabolism of amino acids and derivatives
Drugs			Pyridoxal Phosphate Pyruvic acid Glycine L-Alanine
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 22001757)	Metabolite levels ( 21931564) Urinary metabolites ( 21572414)
Protein-Protein Interactions		8 interactors: AGXT2 ALDOA APP ATP6V1E1 HIVEP1 HSPA8 MUC20 TXN2	2 interactors: ALDOB CYP2E1
Entrez ID		229	64902
HPRD ID		01972	10638
Ensembl ID		ENSG00000136872	ENSG00000113492
Uniprot IDs		P05062	E9PDL7 Q9BYV1
PDB IDs		1QO5 1XDL 1XDM
Enriched GO Terms of Interacting Partners?		Cellular Homeostasis Platelet Degranulation L-alanine Catabolic Process, By Transamination Negative Regulation Of Fibril Organization Secretion By Cell Homeostatic Process Synaptic Growth At Neuromuscular Junction Glycine Biosynthetic Process, By Transamination Of Glyoxylate Secretion Collateral Sprouting In Absence Of Injury Regulation Of Fibril Organization Glyoxylate Catabolic Process Transition Metal Ion Homeostasis Response To Wounding L-alanine Metabolic Process L-alanine Catabolic Process Fructose 1,6-bisphosphate Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Clathrin Coat Disassembly Platelet Activation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Hepatocyte Growth Factor Receptor Signaling Pathway Glyoxylate Metabolic Process Neuron Remodeling Protein Homooligomerization	Fructose Catabolic Process Fructose 1,6-bisphosphate Metabolic Process Monoterpenoid Metabolic Process Vacuolar Proton-transporting V-type ATPase Complex Assembly NADH Oxidation Response To Ozone Monocarboxylic Acid Metabolic Process NADH Metabolic Process Epoxygenase P450 Pathway Fructose Metabolic Process Exogenous Drug Catabolic Process Drug Catabolic Process Carboxylic Acid Metabolic Process Organic Acid Metabolic Process Positive Regulation Of ATPase Activity Drug Metabolic Process Regulation Of ATPase Activity Oxidation-reduction Process NAD Metabolic Process Gluconeogenesis Arachidonic Acid Metabolic Process Hexose Biosynthetic Process Catabolic Process Nicotinamide Nucleotide Metabolic Process Triglyceride Metabolic Process Glycolytic Process Icosanoid Metabolic Process Unsaturated Fatty Acid Metabolic Process Neutral Lipid Metabolic Process Small Molecule Metabolic Process Long-chain Fatty Acid Metabolic Process Isoprenoid Metabolic Process Pyruvate Metabolic Process Xenobiotic Metabolic Process Cellular Response To Xenobiotic Stimulus Response To Ethanol Glucose Metabolic Process Response To Xenobiotic Stimulus Carbohydrate Catabolic Process Carbohydrate Biosynthetic Process Response To Reactive Oxygen Species Pathogenesis Hexose Metabolic Process Monosaccharide Metabolic Process Steroid Metabolic Process Fatty Acid Metabolic Process
Tagcloud ?		aldolase ambp anchor anonymous backcross bikunin d4h9s3e d4nds4 d9s3 dehydratase galt hexabrachion homologues hsa9 hsa9q hxb ifa interspecific levulinate localizations mmu4 orm orosomucoid pax pax5 synteny typed tyrp
Tagcloud (Difference) ?		aldolase ambp anchor anonymous backcross bikunin d4h9s3e d4nds4 d9s3 dehydratase galt hexabrachion homologues hsa9 hsa9q hxb ifa interspecific levulinate localizations mmu4 orm orosomucoid pax pax5 synteny typed tyrp
Tagcloud (Intersection) ?