ZBTB1 and LZTR1

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		ZBTB1	LZTR1
Gene Name		zinc finger and BTB domain containing 1	leucine-zipper-like transcription regulator 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Body
	Molecular Function	DNA Binding Protein Homodimerization Activity Metal Ion Binding Protein Heterodimerization Activity	Sequence-specific DNA Binding Transcription Factor Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of T Cell Mediated Immunity B Cell Differentiation Positive Regulation Of Natural Killer Cell Differentiation T Cell Differentiation In Thymus MRNA Transcription From RNA Polymerase II Promoter Innate Immune Response Positive Regulation Of T Cell Differentiation Thymus Development Protein Homooligomerization Positive Regulation Of Pro-T Cell Differentiation	Regulation Of Transcription, DNA-templated Anatomical Structure Morphogenesis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: AR EWSR1 FAM161A LZTR1 MAML3 NDN PCNA PIM1 SUMO2 TRIM42 UBC ZBTB25 ZNF417 ZNF572	50 interactors: AATF ANKRD53 ASB12 BMPR1B CEBPZ CHAF1A CNOT6L E2F8 EHMT1 FANK1 HCLS1 HDAC4 IKBKG KDM2B L3MBTL3 MCM3 MED16 MED7 MYBL2 NR1H3 PAPOLG PARP1 POLR1B POLR2B POLR2E RAI1 RERE RUVBL1 SCMH1 SND1 SP100 SREBF2 SSX4 STAT1 SUGP2 TAF11 TBX2 TCF19 TFAP2B TRIM5 TUBGCP4 WWP1 ZBTB1 ZNF137P ZNF175 ZNF451 ZNF490 ZNF584 ZNF714 ZZZ3
Entrez ID		22890	8216
HPRD ID		15688	08992
Ensembl ID		ENSG00000126804	ENSG00000099949
Uniprot IDs		Q9Y2K1	Q8N653
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Metabolic Process RNA Biosynthetic Process Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process G1/S Transition Of Mitotic Cell Cycle Transcription Initiation From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process DNA-templated Transcription, Initiation Cellular Nitrogen Compound Metabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Negative Regulation Of Integrin Biosynthetic Process Positive Regulation Of Deoxyribonuclease Activity Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Leading Strand Elongation Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Integrin Biosynthetic Process Regulation Of Cellular Process Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Integrin Biosynthetic Process Cellular Metabolic Process Notch Signaling Pathway Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Cell Growth Positive Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle Intracellular Receptor Signaling Pathway Mitotic Cell Cycle Process Positive Regulation Of Transcription From RNA Polymerase III Promoter Positive Regulation Of Metabolic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Neurotrophin TRK Receptor Signaling Pathway Translesion Synthesis Viral Protein Processing Positive Regulation Of Protein Catabolic Process Cell Proliferation Neurotrophin Signaling Pathway	Transcription, DNA-templated RNA Biosynthetic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process RNA Metabolic Process Regulation Of Gene Expression Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Macromolecule Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Biosynthetic Process Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Cellular Metabolic Process Negative Regulation Of Gene Expression Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Cellular Process DNA-templated Transcription, Initiation Positive Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Metabolic Process Chromosome Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Viral Process Chromatin Organization Viral Process Negative Regulation Of Cellular Metabolic Process Cellular Process Positive Regulation Of Metabolic Process Regulation Of Viral Transcription Chromatin Modification DNA-templated Transcription, Elongation Chromatin Remodeling Positive Regulation Of Viral Transcription
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