LZTR1 and SSX4

Number of citations of the paper that reports this interaction (PubMedID 20211142)
41

Data Source:
BioGRID (two hybrid)

		LZTR1	SSX4
Description		leucine zipper like post translational regulator 1	SSX family member 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endosome Golgi Apparatus Endomembrane System Membrane Cul3-RING Ubiquitin Ligase Complex Recycling Endosome Recycling Endosome Membrane	Nucleus
	Molecular Function	Protein Binding Small GTPase Binding	Protein Binding
	Biological Process	Protein Ubiquitination Negative Regulation Of Ras Protein Signal Transduction	Regulation Of DNA-templated Transcription
Pathways
Drugs
Diseases
GWAS
Interacting Genes		54 interacting genes: AATF ANKRD53 ASB12 BMPR1B CEBPZ CHAF1A CNOT6L E2F8 EHMT1 FANK1 GABARAPL2 HCLS1 HDAC4 HRAS IKBKG KDM2B KRAS L3MBTL3 MCM3 MED16 MED7 MYBL2 NR1H3 NRAS PAPOLG PARP1 POLR1B POLR2B POLR2E RAI1 RERE RUVBL1 SCMH1 SND1 SP100 SREBF2 SSX4 STAT1 SUGP2 TAF11 TBX2 TCF19 TFAP2B TRIM5 TUBGCP4 WWP1 ZBTB1 ZNF137P ZNF175 ZNF451 ZNF490 ZNF584 ZNF714 ZZZ3	6 interacting genes: C14orf119 FLACC1 HIF1A LZTR1 PAX9 XBP1
Entrez ID		8216	6759
HPRD ID		08992	02266
Ensembl ID		ENSG00000099949	ENSG00000268009
Uniprot IDs		A0A384NL67 Q8N653	O60224
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Biosynthetic Process Nucleus Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Primary Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Metabolic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleoplasm Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process DNA Binding Zinc Ion Binding Negative Regulation Of Metabolic Process Transcription By RNA Polymerase II DNA-templated Transcription RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Nuclear Body Nucleic Acid Metabolic Process Nucleolus Ribonucleoside Binding Transcription Coactivator Activity Chromatin Organization RNA Metabolic Process Regulation Of Transcription Initiation By RNA Polymerase II DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Regulator Complex DNA-directed RNA Polymerase Activity Regulation Of DNA-templated Transcription Initiation Chromo Shadow Domain Binding Chromatin Remodeling 5'-3' RNA Polymerase Activity	Glandular Epithelial Cell Maturation Columnar/cuboidal Epithelial Cell Maturation Epithelial Cell Maturation RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Elastin Metabolic Process Carbohydrate Homeostasis Epithelial Cell Differentiation Involved In Mammary Gland Alveolus Development Glucose Homeostasis Hemoglobin Biosynthetic Process Vascular Endothelial Growth Factor Production Developmental Maturation Hypoxia-inducible Factor-1alpha Signaling Pathway Positive Regulation Of Autophagy Negative Regulation Of Intracellular Signal Transduction B-1 B Cell Homeostasis Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Intrinsic Apoptotic Signaling Pathway Cellular Response To Oxidative Stress Cis-regulatory Region Sequence-specific DNA Binding Motile Cilium Cell Maturation Regulation Of TOR Signaling Neural Fold Elevation Formation Intestinal Epithelial Cell Maturation Positive Regulation Of Angiogenesis Positive Regulation Of Epithelial Cell Proliferation Regulation Of Anatomical Structure Morphogenesis Histone Deacetylase Binding RNA Polymerase II Transcription Regulator Complex Positive Regulation Of Vasculature Development Tissue Development Intracellular Glucose Homeostasis Positive Regulation Of Chemokine-mediated Signaling Pathway Connective Tissue Replacement Involved In Inflammatory Response Wound Healing Positive Regulation Of Vascular Wound Healing Response To Insulin-like Growth Factor Stimulus Cellular Response To Fructose Stimulus Epithelial Cell Maturation Involved In Salivary Gland Development Positive Regulation Of Lactation Positive Regulation Of Protein Acetylation Regulation Of Lactation Positive Regulation Of Plasma Cell Differentiation Outer Dense Fiber Iris Morphogenesis Intracellular Oxygen Homeostasis Negative Regulation Of Mesenchymal Cell Apoptotic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Negative Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Hormone Biosynthetic Process Connective Tissue Replacement
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