ZBTB1 and ZNF572

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		ZBTB1	ZNF572
Description		zinc finger and BTB domain containing 1	zinc finger protein 572
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Body Nuclear Membrane	Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Protein Homodimerization Activity Metal Ion Binding Protein Heterodimerization Activity K63-linked Polyubiquitin Modification-dependent Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cytokine Production Immune System Process Regulation Of Immune System Process Positive Regulation Of T Cell Mediated Immunity DNA Repair Chromatin Remodeling DNA Damage Response Translesion Synthesis Cell Differentiation B Cell Differentiation Positive Regulation Of Natural Killer Cell Differentiation T Cell Differentiation In Thymus Cellular Response To UV MRNA Transcription By RNA Polymerase II Innate Immune Response Positive Regulation Of T Cell Differentiation Thymus Development Protein Homooligomerization Positive Regulation Of Pro-T Cell Differentiation	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cytokine Production Regulation Of Immune System Process
Pathways
Drugs
Diseases
GWAS		Lymphocyte count ( 32888494) Neutrophil percentage of white cells ( 32888494) Urinary albumin-to-creatinine ratio ( 31630189)	Metabolite levels ( 23823483)
Interacting Genes		22 interacting genes: AKR7A2 AR EWSR1 FAM161A FANCG HEMGN KAT5 LZTR1 MAML3 MFAP1 NDN PCNA PIH1D2 PIM1 SCNM1 TRAF1 TRIM42 UBC UBE2I ZBTB25 ZNF417 ZNF572	60 interacting genes: ATOSB BEGAIN BOLA1 CADPS CARD9 CBY2 CCDC102B CCDC136 CCDC33 CDR2L CEP57L1 CEP70 CPNE7 DEUP1 DRC4 FSD2 GOLGA2 GPR50 HAP1 HOOK1 HOOK2 IL16 KATNBL1 KIF9 KIFC3 KLC3 KRT31 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 LZTS1 LZTS2 MDFI MEOX2 MLLT3 MTUS2 NDEL1 PRPH REL SPAG5 TFIP11 TRAF1 TRAF2 TRIM27 TRIM54 VIM WTAP YJU2B ZBTB1 ZBTB8A ZNF165 ZNF250 ZNF383 ZNF417 ZNF57 ZNF774 ZNF835
Entrez ID		22890	137209
HPRD ID		15688	15851
Ensembl ID		ENSG00000126804	ENSG00000180938
Uniprot IDs		Q9Y2K1	Q7Z3I7
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleoplasm Regulation Of DNA-templated Transcription Negative Regulation Of DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process Zinc Ion Binding Regulation Of RNA Metabolic Process Transcription Factor Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process	Microtubule Binding Microtubule Intermediate Filament Keratin Filament Cytoskeleton Identical Protein Binding Microtubule-based Process Kinesin Complex Cytoskeleton-dependent Intracellular Transport Protein Binding Centrosome FHF Complex Microtubule Cytoskeleton Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Protein Localization To Perinuclear Region Of Cytoplasm Microtubule-based Movement Ciliary Rootlet Thioesterase Binding Establishment Of Vesicle Localization Vesicle Transport Along Microtubule Cytoskeleton Organization Vesicle Localization
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