LZTR1 and KDM2B

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		LZTR1	KDM2B
Gene Name		leucine-zipper-like transcription regulator 1	lysine (K)-specific demethylase 2B
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Nucleoplasm Nucleolus PcG Protein Complex
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity	DNA Binding Protein Binding Zinc Ion Binding RRNA Binding Histone Demethylase Activity Histone Demethylase Activity (H3-K36 Specific)
	Biological Process	Regulation Of Transcription, DNA-templated Anatomical Structure Morphogenesis	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Transcription, DNA-templated Spermatogenesis Histone Demethylation Midbrain-hindbrain Boundary Morphogenesis Fourth Ventricle Development Lateral Ventricle Development Third Ventricle Development Initiation Of Neural Tube Closure Forebrain Development Midbrain Development Hindbrain Development Histone H2A Monoubiquitination Negative Regulation Of Neuron Apoptotic Process Embryonic Camera-type Eye Morphogenesis Oxidation-reduction Process Histone H3-K36 Demethylation Negative Regulation Of Neural Precursor Cell Proliferation
Pathways			Chromatin modifying enzymes Chromatin organization HDMs demethylate histones
Drugs
Diseases
GWAS
Protein-Protein Interactions		50 interactors: AATF ANKRD53 ASB12 BMPR1B CEBPZ CHAF1A CNOT6L E2F8 EHMT1 FANK1 HCLS1 HDAC4 IKBKG KDM2B L3MBTL3 MCM3 MED16 MED7 MYBL2 NR1H3 PAPOLG PARP1 POLR1B POLR2B POLR2E RAI1 RERE RUVBL1 SCMH1 SND1 SP100 SREBF2 SSX4 STAT1 SUGP2 TAF11 TBX2 TCF19 TFAP2B TRIM5 TUBGCP4 WWP1 ZBTB1 ZNF137P ZNF175 ZNF451 ZNF490 ZNF584 ZNF714 ZZZ3	4 interactors: CEBPE HIST1H3A LZTR1 UBE2D1
Entrez ID		8216	84678
HPRD ID		08992	12362
Ensembl ID		ENSG00000099949	ENSG00000089094
Uniprot IDs		Q8N653	Q8NHM5
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process RNA Metabolic Process Regulation Of Gene Expression Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Macromolecule Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Biosynthetic Process Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Cellular Metabolic Process Negative Regulation Of Gene Expression Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Cellular Process DNA-templated Transcription, Initiation Positive Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Metabolic Process Chromosome Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Viral Process Chromatin Organization Viral Process Negative Regulation Of Cellular Metabolic Process Cellular Process Positive Regulation Of Metabolic Process Regulation Of Viral Transcription Chromatin Modification DNA-templated Transcription, Elongation Chromatin Remodeling Positive Regulation Of Viral Transcription	Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process DNA Replication-dependent Nucleosome Assembly Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process DNA Methylation On Cytosine Chromatin Silencing At RDNA
Tagcloud ?			7b aberrant analog array axis azacitidine bypassed cd34 cyclopentanyl deazaadenosine di dysregulated dznep ezh2 g0 h3k27 h3k27me3 hypomethylating hypothesized landscape let marrows methylated nanostring p16 preliminary preventing repression tri
Tagcloud (Difference) ?			7b aberrant analog array axis azacitidine bypassed cd34 cyclopentanyl deazaadenosine di dysregulated dznep ezh2 g0 h3k27 h3k27me3 hypomethylating hypothesized landscape let marrows methylated nanostring p16 preliminary preventing repression tri
Tagcloud (Intersection) ?