VASH1 and DHPS

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		VASH1	DHPS
Description		vasohibin 1	deoxyhypusine synthase
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Endoplasmic Reticulum Apical Part Of Cell	Cytoplasm Cytosol
	Molecular Function	Actin Binding Carboxypeptidase Activity Metallocarboxypeptidase Activity Protein Binding Peptidase Activity Hydrolase Activity Tubulin-tyrosine Carboxypeptidase	Protein Binding Transferase Activity Deoxyhypusine Synthase Activity Identical Protein Binding
	Biological Process	Angiogenesis Negative Regulation Of Endothelial Cell Proliferation Proteolysis Response To Wounding Negative Regulation Of Angiogenesis Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Angiogenesis Regulation Of Cell Cycle Placenta Blood Vessel Development Labyrinthine Layer Blood Vessel Development Negative Regulation Of Lymphangiogenesis Regulation Of Cellular Senescence	Translation Spermidine Metabolic Process Positive Regulation Of Cell Population Proliferation Positive Regulation Of T Cell Proliferation Glucose Homeostasis Spermidine Catabolic Process Protein Maturation
Pathways		Carboxyterminal post-translational modifications of tubulin	Hypusine synthesis from eIF5A-lysine
Drugs			1-Guanidinium-7-Aminoheptane
Diseases
GWAS			Platelet distribution width ( 32888494)
Interacting Genes		1 interacting genes: DHPS	16 interacting genes: BRCA1 EIF5A EIF5A2 LNX1 MEOX2 NIF3L1 NTAQ1 NUDT18 PAX6 PTPRH RAB27B RBP1 REL RPL9 VASH1 ZNF138
Entrez ID		22846	1725
HPRD ID		12353	02969
Ensembl ID		ENSG00000071246	ENSG00000095059
Uniprot IDs		Q7L8A9	P49366
PDB IDs		6J4U 6J7B 6J8F 6J8N 6J8O 6J91 6J9H 6K81 6LPG 6NVQ 6OCF 6OCG 6OCH 6WSL	1DHS 1RLZ 1ROZ 1RQD 6P4V 6PGR 6WKZ 6WL6 6XXH 6XXI 6XXJ 6XXK 6XXL 6XXM 7A6S 7A6T 8A0E 8A0F 8A0G 8PVU 8R3U
Enriched GO Terms of Interacting Partners?		Spermidine Catabolic Process Polyamine Catabolic Process Deoxyhypusine Synthase Activity Cholesterol Storage Regulation Of Isoprenoid Metabolic Process Spermidine Metabolic Process Glycolipid Transport Sterol Binding Chemical Homeostasis Polyamine Metabolic Process Cholesterol Transfer Activity Intracellular Sterol Transport Intracellular Cholesterol Transport Cholesterol Efflux Lipid Storage Intracellular Lipid Transport Homeostatic Process Cholesterol Binding Macromolecule Biosynthetic Process Biogenic Amine Metabolic Process Cholesterol Transport Amine Metabolic Process Phospholipid Transport Sterol Homeostasis Sterol Transport Azurophil Granule Lumen Lysosomal Lumen Carbohydrate Derivative Transport Cholesterol Homeostasis Positive Regulation Of T Cell Proliferation Cholesterol Metabolic Process Sterol Metabolic Process	Regulation Of Translational Termination Positive Regulation Of Translational Termination Positive Regulation Of Translational Elongation Regulation Of Translational Elongation Translation Elongation Factor Activity Regulation Of Protein-containing Complex Disassembly Cytoplasm Positive Regulation Of Protein-containing Complex Disassembly Forebrain-midbrain Boundary Formation Pancreatic A Cell Development Protein-N-terminal Glutamine Amidohydrolase Activity 8-hydroxy-dADP Phosphatase Activity 8-oxo-GDP Phosphatase Activity DGDP Catabolic Process DADP Catabolic Process
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