MRAS and RASIP1

Number of citations of the paper that reports this interaction (PMID 15031288)
17

Data Source:
HPRD (in vitro)

		MRAS	RASIP1
Gene Name		muscle RAS oncogene homolog	Ras interacting protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Extracellular Vesicular Exosome	Golgi Stack Perinuclear Region Of Cytoplasm
	Molecular Function	GTPase Activity GTP Binding GTP-dependent Protein Binding
	Biological Process	Ras Protein Signal Transduction Multicellular Organismal Development Muscle Organ Development Actin Cytoskeleton Organization	Angiogenesis Vasculogenesis Signal Transduction Negative Regulation Of Autophagy Regulation Of Rho GTPase Activity Branching Morphogenesis Of An Epithelial Tube
Pathways
Drugs
Diseases
GWAS		Coronary heart disease ( 19198612 21378990)	Bipolar disorder ( 21926972) Crohn's disease ( 21102463) Dietary macronutrient intake ( 23372041) Retinal vascular caliber ( 21060863)
Protein-Protein Interactions		10 interactors: BRAF MLLT4 PIK3CA RAF1 RALGDS RAPGEF5 RAPGEF6 RASIP1 RASSF5 TCEB1	8 interactors: ARFGAP1 HRAS LDB2 MRAS RAP1A RAP2A RRAS RRAS2
Entrez ID		22808	54922
HPRD ID		06662	15214
Ensembl ID		ENSG00000158186	ENSG00000105538
Uniprot IDs		O14807 Q6FGP0 Q8WVM9	Q5U651 Q7L251 Q8IUR2
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Rap GTPase Activity Regulation Of Rap GTPase Activity Regulation Of Rap Protein Signal Transduction Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Metabolic Process Regulation Of Catalytic Activity Positive Regulation Of Catalytic Activity Regulation Of Intracellular Signal Transduction Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Intracellular Signal Transduction Small GTPase Mediated Signal Transduction Cellular Response To Stimulus Regulation Of Ras Protein Signal Transduction Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of GTPase Activity Regulation Of Peptidyl-serine Phosphorylation Signal Transduction Regulation Of Metabolic Process Signaling Cell Communication Response To Stimulus Regulation Of Signal Transduction Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Ras GTPase Activity Regulation Of Signaling Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Cellular Response To Growth Factor Stimulus Response To Growth Factor Ras Protein Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of GTPase Activity Activation Of MAPKK Activity Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Modification Process Somatic Stem Cell Maintenance Death-inducing Signaling Complex Assembly Regulation Of Cellular Amino Acid Metabolic Process Positive Regulation Of Hydrolase Activity Positive Regulation Of Ras GTPase Activity Response To Peptide Hormone Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Kinase Activity Hypomethylation Of CpG Island Response To Peptide Positive Regulation Of Kinase Activity Regulation Of Cellular Ketone Metabolic Process Regulation Of Cellular Process	Ras Protein Signal Transduction Small GTPase Mediated Signal Transduction Rap Protein Signal Transduction Intracellular Signal Transduction Regulation Of Cell Migration Regulation Of Phosphorylation Regulation Of ERK1 And ERK2 Cascade Regulation Of MAPK Cascade Regulation Of Cell Motility Regulation Of Locomotion Regulation Of Phosphorus Metabolic Process Regulation Of Cellular Component Movement Positive Regulation Of Protein Phosphorylation Regulation Of Intracellular Signal Transduction Positive Regulation Of Phosphorylation Positive Regulation Of Protein Modification Process Signal Transduction Cell Differentiation Activation Of MAPKK Activity Developmental Process Regulation Of Protein Phosphorylation Signaling Positive Regulation Of Cellular Protein Metabolic Process Cell Communication Positive Regulation Of Protein Kinase Activity Positive Regulation Of Protein Metabolic Process Regulation Of Cell Projection Organization Positive Regulation Of Kinase Activity Regulation Of Ras GTPase Activity System Development Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transferase Activity Cellular Response To Stimulus Positive Regulation Of ERK1 And ERK2 Cascade Actin Cytoskeleton Organization Regulation Of Signal Transduction Actin Filament-based Process Generation Of Neurons Regulation Of Ras Protein Signal Transduction Regulation Of Cell Differentiation Multicellular Organismal Development Neurogenesis Regulation Of JNK Cascade Positive Regulation Of GTPase Activity Anatomical Structure Development Regulation Of Signaling Regulation Of Protein Kinase Activity Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Rac Protein Signal Transduction Regulation Of Stress-activated MAPK Cascade
Tagcloud ?		acetylcholine anion antihypertensive assume bioavailability cuff cyclooxygenase deleterious deoxycorticosterone doca gavage hypertension hypertensive mesenteric myograph nad nak nakatpase ouabain reasonable relaxation rosta rostafuroxin salt sbp uninephrectomized wire wistar
Tagcloud (Difference) ?		acetylcholine anion antihypertensive assume bioavailability cuff cyclooxygenase deleterious deoxycorticosterone doca gavage hypertension hypertensive mesenteric myograph nad nak nakatpase ouabain reasonable relaxation rosta rostafuroxin salt sbp uninephrectomized wire wistar
Tagcloud (Intersection) ?