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NID2 and PRELP
Number of citations of the paper that reports this interaction (PMID
11847210
)
16
Data Source:
BioGRID
(pull down)
NID2
PRELP
Gene Name
nidogen 2 (osteonidogen)
proline/arginine-rich end leucine-rich repeat protein
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Region
Basement Membrane
Cell Surface
Extracellular Matrix
Extracellular Vesicular Exosome
Extracellular Region
Proteinaceous Extracellular Matrix
Golgi Lumen
Extracellular Matrix
Vesicle
Lysosomal Lumen
Extracellular Vesicular Exosome
Molecular Function
Calcium Ion Binding
Protein Binding
Collagen Binding
Extracellular Matrix Structural Constituent
Heparin Binding
Biological Process
Cell Adhesion
Cell-matrix Adhesion
Extracellular Matrix Organization
Basement Membrane Organization
Skeletal System Development
Carbohydrate Metabolic Process
Cell Aging
Pathogenesis
Keratan Sulfate Biosynthetic Process
Glycosaminoglycan Metabolic Process
Keratan Sulfate Metabolic Process
Keratan Sulfate Catabolic Process
Small Molecule Metabolic Process
Pathways
Laminin interactions
MPS IIIB - Sanfilippo syndrome B
Diseases of glycosylation
Defective B4GALT7 causes EDS, progeroid type
MPS I - Hurler syndrome
Keratan sulfate/keratin metabolism
MPS IX - Natowicz syndrome
Defective SLC26A2 causes chondrodysplasias
Glycosaminoglycan metabolism
Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)
Defective CHST14 causes EDS, musculocontractural type
Defective PAPSS2 causes SEMD-PA
MPS IIIA - Sanfilippo syndrome A
Myoclonic epilepsy of Lafora
Glycogen storage diseases
Defective CHST6 causes MCDC1
MPS IIID - Sanfilippo syndrome D
MPS IIIC - Sanfilippo syndrome C
Keratan sulfate biosynthesis
Diseases associated with glycosaminoglycan metabolism
Mucopolysaccharidoses
Keratan sulfate degradation
Defective EXT2 causes exostoses 2
MPS II - Hunter syndrome
Defective B3GAT3 causes JDSSDHD
Defective CHST3 causes SEDCJD
Defective EXT1 causes exostoses 1, TRPS2 and CHDS
MPS IV - Morquio syndrome A
MPS IV - Morquio syndrome B
Defective CHSY1 causes TPBS
Metabolism of carbohydrates
MPS VII - Sly syndrome
MPS VI - Maroteaux-Lamy syndrome
Drugs
Diseases
GWAS
Pulmonary function (
17903307
)
Protein-Protein Interactions
9 interactors:
COL13A1
COL1A1
COL4A1
ELN
HSPG2
KRTAP10-3
LAMC1
PRELP
SKIL
7 interactors:
COL1A1
COL2A1
FBLN2
FN1
HSPG2
NID1
NID2
Entrez ID
22795
5549
HPRD ID
05654
03556
Ensembl ID
ENSG00000087303
ENSG00000188783
Uniprot IDs
Q14112
P51888
PDB IDs
Enriched GO Terms of Interacting Partners
?
Extracellular Matrix Disassembly
Extracellular Matrix Organization
Extracellular Structure Organization
Endochondral Ossification
Anatomical Structure Morphogenesis
System Development
Collagen Catabolic Process
Collagen Metabolic Process
Endochondral Bone Morphogenesis
Multicellular Organismal Macromolecule Metabolic Process
Multicellular Organismal Development
Multicellular Organismal Metabolic Process
Anatomical Structure Development
Tissue Development
Protein Heterotrimerization
Bone Morphogenesis
Developmental Process
Skeletal System Development
Bone Development
Protein Trimerization
Cartilage Development Involved In Endochondral Bone Morphogenesis
Skeletal System Morphogenesis
Ossification
Organ Development
Catabolic Process
Striated Muscle Tissue Development
Muscle Tissue Development
Glycosaminoglycan Catabolic Process
Cellular Response To Amino Acid Stimulus
Cell Differentiation
Organ Morphogenesis
Anatomical Structure Formation Involved In Morphogenesis
Cellular Response To Fluoride
Glycosaminoglycan Biosynthetic Process
Blood Vessel Development
Vasculature Development
Response To Amino Acid
Tooth Eruption
Response To Fluoride
Protein Heterooligomerization
Skeletal Muscle Tissue Development
Skeletal Muscle Organ Development
Positive Regulation Of Cell Morphogenesis Involved In Differentiation
Embryonic Skeletal System Development
Cellular Response To Acid Chemical
Glycosaminoglycan Metabolic Process
Retinal Blood Vessel Morphogenesis
Cellular Response To Vitamin E
Cellular Response To Transforming Growth Factor Beta Stimulus
Response To Transforming Growth Factor Beta
Extracellular Matrix Organization
Extracellular Structure Organization
Extracellular Matrix Disassembly
Cartilage Development Involved In Endochondral Bone Morphogenesis
Endochondral Ossification
Endochondral Bone Morphogenesis
Bone Morphogenesis
Embryonic Skeletal System Development
Cell-matrix Adhesion
Basement Membrane Organization
Regulation Of Cell-substrate Adhesion
Cartilage Development
Cell-substrate Adhesion
Bone Development
Connective Tissue Development
Skeletal System Morphogenesis
Ossification
Cardiovascular System Development
Anatomical Structure Formation Involved In Morphogenesis
Collagen Fibril Organization
Collagen Catabolic Process
Embryo Development
Collagen Metabolic Process
Multicellular Organismal Macromolecule Metabolic Process
Chondrocyte Differentiation
Multicellular Organismal Metabolic Process
Cellular Response To Fluoride
Blood Vessel Development
Vasculature Development
Proteoglycan Metabolic Process
Skeletal System Development
Positive Regulation Of Cell-substrate Adhesion
Regulation Of Cell Adhesion
Tooth Eruption
Response To Fluoride
Embryonic Skeletal System Morphogenesis
Embryonic Morphogenesis
Tissue Development
Sensory Perception Of Sound
Positive Regulation Of Cell Morphogenesis Involved In Differentiation
Visual Perception
Calcium-independent Cell-matrix Adhesion
Chordate Embryonic Development
Sensory Perception Of Light Stimulus
Embryo Development Ending In Birth Or Egg Hatching
Sensory Perception Of Mechanical Stimulus
Platelet Activation
Cellular Response To Vitamin E
Leukocyte Migration
Organ Morphogenesis
Tagcloud
?
abundance
adenocarcinomas
aversely
clues
die
dismal
ductal
extend
galectin
lethal
lgals1
pancreas
pancreatic
pdac
personalized
prolargin
proteome
proteomes
rarely
rps8
s8
sts
survive
survivors
tgfbeta
top
upstream
vegfa
vlts
Tagcloud (Difference)
?
abundance
adenocarcinomas
aversely
clues
die
dismal
ductal
extend
galectin
lethal
lgals1
pancreas
pancreatic
pdac
personalized
prolargin
proteome
proteomes
rarely
rps8
s8
sts
survive
survivors
tgfbeta
top
upstream
vegfa
vlts
Tagcloud (Intersection)
?