ADGRG3 and CTXN3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ADGRG3	CTXN3
Description		adhesion G protein-coupled receptor G3	cortexin 3
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Specific Granule Membrane	Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity G Protein-coupled Receptor Activity Protein Binding	Protein Binding
	Biological Process	Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway B Cell Differentiation Regulation Of Cell Migration Negative Regulation Of CREB Transcription Factor Activity Negative Regulation Of Non-canonical NF-kappaB Signal Transduction
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS			Brain imaging in schizophrenia (dorsolateral prefrontal cortex interaction) ( 19023125) Plasma amyloid beta peptide concentrations (ABx-42) ( 24535457)
Interacting Genes		12 interacting genes: ARLN ATP6V0B C3orf52 CTXN3 GIMAP5 LHFPL5 PLP1 RPRM SEC22A TEX264 UPK2 VSTM1	59 interacting genes: ADGRG3 AQP6 AQP9 ATP1B3 BIK BTN2A1 CD300E CD53 CD79A CERS4 CLDN14 CLEC17A CLEC7A CLRN1 COQ9 CPLX4 CREB3L1 CTLA4 EDA ERGIC3 FAM209A FFAR3 FUT7 GJA8 GJB1 GJB5 GPR152 GPR42 GPR61 IFNLR1 KASH5 KIR3DL3 KLRC1 LAPTM4B LDLRAD1 LHFPL5 LSMEM2 MFF MGST2 MTIF3 NCAPH2 OPRD1 OPRM1 PACC1 PLPP5 PVR SCN3B SLC10A2 SPACA1 STOM TLCD4 TM4SF19 TMEM106C TMEM167B TMEM179B TMEM31 TMPRSS2 TMX2 TSPAN12
Entrez ID		222487	613212
HPRD ID		17073	18888
Ensembl ID		ENSG00000182885	ENSG00000205279
Uniprot IDs		B4DVW2 F8W8F7 H3BRU4 Q86Y34	Q4LDR2
PDB IDs		7D76 7D77 7QU8
Enriched GO Terms of Interacting Partners?		Membrane	Membrane Plasma Membrane Protein Binding PH-gated Chloride Channel Activity Connexin Complex Gap Junction Channel Activity Gap Junction Immune Response-activating Cell Surface Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway G Protein-coupled Opioid Receptor Activity G Protein-coupled Receptor Activity Immune Response-regulating Cell Surface Receptor Signaling Pathway G Protein-coupled Opioid Receptor Signaling Pathway Immune System Process Immune Response-regulating Signaling Pathway
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