ADGRG3 and RPRM

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ADGRG3	RPRM
Description		adhesion G protein-coupled receptor G3	reprimo, TP53 dependent G2 arrest mediator homolog
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Specific Granule Membrane	Cytoplasm Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity G Protein-coupled Receptor Activity Protein Binding	Protein Binding
	Biological Process	Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway B Cell Differentiation Regulation Of Cell Migration Negative Regulation Of CREB Transcription Factor Activity Negative Regulation Of Non-canonical NF-kappaB Signal Transduction	Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS			Anti-saccade response ( 29064472) Blood trace element (Zn levels) ( 23720494) Heel bone mineral density ( 30598549) Lung cancer ( 28604730) Recurrent major depressive disorder x sex interaction ( 34099189)
Interacting Genes		12 interacting genes: ARLN ATP6V0B C3orf52 CTXN3 GIMAP5 LHFPL5 PLP1 RPRM SEC22A TEX264 UPK2 VSTM1	80 interacting genes: ADGRG3 AMIGO1 AQP6 ARFIP1 ASGR2 BNIP3 BSCL2 BTNL9 C16orf54 CD33 CD53 CD69 CLDN5 CLDN7 CLDN9 CLEC17A CLEC2D COQ8A CREB3 CXorf66 EHHADH EMP1 FAM209A FAM210B FATE1 FBXL19 FCGR1A FFAR2 FGD2 FKBP7 FNDC9 GAD2 GJA5 GJB3 GJB5 GNG13 GPR37L1 GPR42 GPX8 HHLA2 HIP1 HSD17B13 KCNJ6 LAPTM5 LHFPL5 LMNA LPAR6 MPP1 MS4A4A MTIF3 OPRD1 OPRM1 PBX3 PDZK1IP1 PLEKHF2 PNKP SCAND1 SDCBP SENP2 SLC18A1 SLC38A1 SMIM3 SNX11 SNX12 SNX3 SPACA1 SPCS1 STOM SUSD3 SYT16 TM4SF18 TMEM106C TMEM237 TMEM79 TMEM80 TMEM86B TSPO2 TTPA WDFY2 ZDHHC22
Entrez ID		222487	56475
HPRD ID		17073	18002
Ensembl ID		ENSG00000182885	ENSG00000177519
Uniprot IDs		B4DVW2 F8W8F7 H3BRU4 Q86Y34	Q9NS64
PDB IDs		7D76 7D77 7QU8
Enriched GO Terms of Interacting Partners?		Membrane	Membrane Protein Binding Plasma Membrane Negative Regulation Of Early Endosome To Late Endosome Transport Connexin Complex Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Gap Junction Channel Activity Endoplasmic Reticulum Phosphatidylinositol Binding External Side Of Plasma Membrane Gap Junction Gamma-aminobutyric Acid Biosynthetic Process Phosphatidylinositol Phosphate Binding Late Endosome To Golgi Transport
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