CTXN3 and PACC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CTXN3	PACC1
Description		cortexin 3	proton activated chloride channel 1
Image		No pdb structure
GO Annotations	Cellular Component	Membrane	Plasma Membrane Cell Surface Membrane Chloride Channel Complex
	Molecular Function	Protein Binding	Chloride Channel Activity Protein Binding PH-gated Chloride Channel Activity
	Biological Process		Monoatomic Ion Transport Chloride Transport Monoatomic Ion Transmembrane Transport Chloride Transmembrane Transport
Pathways
Drugs
Diseases
GWAS		Brain imaging in schizophrenia (dorsolateral prefrontal cortex interaction) ( 19023125) Plasma amyloid beta peptide concentrations (ABx-42) ( 24535457)
Interacting Genes		59 interacting genes: ADGRG3 AQP6 AQP9 ATP1B3 BIK BTN2A1 CD300E CD53 CD79A CERS4 CLDN14 CLEC17A CLEC7A CLRN1 COQ9 CPLX4 CREB3L1 CTLA4 EDA ERGIC3 FAM209A FFAR3 FUT7 GJA8 GJB1 GJB5 GPR152 GPR42 GPR61 IFNLR1 KASH5 KIR3DL3 KLRC1 LAPTM4B LDLRAD1 LHFPL5 LSMEM2 MFF MGST2 MTIF3 NCAPH2 OPRD1 OPRM1 PACC1 PLPP5 PVR SCN3B SLC10A2 SPACA1 STOM TLCD4 TM4SF19 TMEM106C TMEM167B TMEM179B TMEM31 TMPRSS2 TMX2 TSPAN12	4 interacting genes: CTXN3 PLLP PLP2 SEC22A
Entrez ID		613212	55248
HPRD ID		18888	07707
Ensembl ID		ENSG00000205279	ENSG00000065600
Uniprot IDs		Q4LDR2	B4DHQ5 Q9H813
PDB IDs			7JNA 7JNC 7SQF 7SQG 7SQH 8EQ4 8FBL
Enriched GO Terms of Interacting Partners?		Membrane Plasma Membrane Protein Binding PH-gated Chloride Channel Activity Connexin Complex Gap Junction Channel Activity Gap Junction Immune Response-activating Cell Surface Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway G Protein-coupled Opioid Receptor Activity G Protein-coupled Receptor Activity Immune Response-regulating Cell Surface Receptor Signaling Pathway G Protein-coupled Opioid Receptor Signaling Pathway Immune System Process Immune Response-regulating Signaling Pathway	Regulation Of Transcytosis Compact Myelin Chemokine Binding Monoatomic Ion Transmembrane Transporter Activity Structural Constituent Of Myelin Sheath Myelin Assembly
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