ADGRG3 and C3orf52

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ADGRG3	C3orf52
Description		adhesion G protein-coupled receptor G3	chromosome 3 open reading frame 52
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Specific Granule Membrane	Endoplasmic Reticulum Plasma Membrane Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity G Protein-coupled Receptor Activity Protein Binding	Protein Binding
	Biological Process	Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway B Cell Differentiation Regulation Of Cell Migration Negative Regulation Of CREB Transcription Factor Activity Negative Regulation Of Non-canonical NF-kappaB Signal Transduction
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS			Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494)
Interacting Genes		12 interacting genes: ARLN ATP6V0B C3orf52 CTXN3 GIMAP5 LHFPL5 PLP1 RPRM SEC22A TEX264 UPK2 VSTM1	74 interacting genes: ADGRG3 AGER AHNAK2 AMIGO1 AQP6 ATP1B4 BIK CCL21 CCL26 CD33 CHST13 CLDN7 CLEC10A CNMD CPLX4 CREB3 DEXI ERGIC3 ERP29 ESAM FAM209A FFAR2 FKBP7 FNDC9 FOLH1 FUT3 GJA8 GJB1 GOLM2 GORAB GPX8 HHLA2 HSD17B13 KEL KIR2DL3 KLRC1 LEUTX LHFPL5 LMNA LRRC25 MFF MGST2 MGST3 MRGPRX3 MUC1 NCR3LG1 NEMP1 NPDC1 NSG2 PVR QPCTL REEP3 RNF150 SAR1A SGTA SLC10A1 SLC10A2 SLC10A6 SLC16A2 SLC23A2 SLC39A2 SPRING1 ST6GALNAC3 STOM SYNE4 TIMMDC1 TMEM179B TMEM237 TMEM45B TMEM52B TMEM80 TMPRSS2 UPK2 ZNRF3
Entrez ID		222487	79669
HPRD ID		17073	08018
Ensembl ID		ENSG00000182885	ENSG00000114529
Uniprot IDs		B4DVW2 F8W8F7 H3BRU4 Q86Y34	Q5BVD1
PDB IDs		7D76 7D77 7QU8
Enriched GO Terms of Interacting Partners?		Membrane	Membrane Protein Binding Bile Acid:sodium Symporter Activity Plasma Membrane Glutathione Peroxidase Activity Bile Acid And Bile Salt Transport Leukotriene-C4 Synthase Activity
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