CTXN3 and KIR3DL3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CTXN3	KIR3DL3
Description		cortexin 3	killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane	Plasma Membrane Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		Immune Response-regulating Signaling Pathway Cell Communication
Pathways
Drugs
Diseases
GWAS		Brain imaging in schizophrenia (dorsolateral prefrontal cortex interaction) ( 19023125) Plasma amyloid beta peptide concentrations (ABx-42) ( 24535457)	Monocyte percentage of white cells ( 32888494)
Interacting Genes		59 interacting genes: ADGRG3 AQP6 AQP9 ATP1B3 BIK BTN2A1 CD300E CD53 CD79A CERS4 CLDN14 CLEC17A CLEC7A CLRN1 COQ9 CPLX4 CREB3L1 CTLA4 EDA ERGIC3 FAM209A FFAR3 FUT7 GJA8 GJB1 GJB5 GPR152 GPR42 GPR61 IFNLR1 KASH5 KIR3DL3 KLRC1 LAPTM4B LDLRAD1 LHFPL5 LSMEM2 MFF MGST2 MTIF3 NCAPH2 OPRD1 OPRM1 PACC1 PLPP5 PVR SCN3B SLC10A2 SPACA1 STOM TLCD4 TM4SF19 TMEM106C TMEM167B TMEM179B TMEM31 TMPRSS2 TMX2 TSPAN12	23 interacting genes: ADAM33 AGTRAP ASIC1 C5 CD53 CMTM5 CTXN3 EDDM3B EMP3 GIMAP5 JAGN1 LAPTM5 NINJ2 OLFM4 SERP1 SLC35A1 SLC41A2 SMIM3 SYS1 TAFA2 TNMD UPK2 VAMP5
Entrez ID		613212	115653
HPRD ID		18888	17236
Ensembl ID		ENSG00000205279	ENSG00000242019
Uniprot IDs		Q4LDR2	A0A8I5QEB2
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Plasma Membrane Protein Binding PH-gated Chloride Channel Activity Connexin Complex Gap Junction Channel Activity Gap Junction Immune Response-activating Cell Surface Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway G Protein-coupled Opioid Receptor Activity G Protein-coupled Receptor Activity Immune Response-regulating Cell Surface Receptor Signaling Pathway G Protein-coupled Opioid Receptor Signaling Pathway Immune System Process Immune Response-regulating Signaling Pathway	Membrane Inorganic Cation Transmembrane Transporter Activity
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