CTXN3 and LAPTM4B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CTXN3	LAPTM4B
Description		cortexin 3	lysosomal protein transmembrane 4 beta
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane	Lysosome Lysosomal Membrane Endosome Early Endosome Plasma Membrane Endosome Membrane Endomembrane System Membrane Late Endosome Membrane Multivesicular Body Membrane Cell Projection Multivesicular Body, Internal Vesicle
	Molecular Function	Protein Binding	Protein Binding Kinase Binding Ubiquitin Protein Ligase Binding Ceramide Binding Phosphatidylinositol Bisphosphate Binding
	Biological Process		Endosome Organization Endosome Transport Via Multivesicular Body Sorting Pathway Negative Regulation Of Transforming Growth Factor Beta1 Production Regulation Of Lysosomal Membrane Permeability Negative Regulation Of Lysosomal Protein Catabolic Process Regulation Of Lysosome Organization
Pathways
Drugs
Diseases
GWAS		Brain imaging in schizophrenia (dorsolateral prefrontal cortex interaction) ( 19023125) Plasma amyloid beta peptide concentrations (ABx-42) ( 24535457)	Metabolite levels ( 23823483) QT interval ( 24952745)
Interacting Genes		59 interacting genes: ADGRG3 AQP6 AQP9 ATP1B3 BIK BTN2A1 CD300E CD53 CD79A CERS4 CLDN14 CLEC17A CLEC7A CLRN1 COQ9 CPLX4 CREB3L1 CTLA4 EDA ERGIC3 FAM209A FFAR3 FUT7 GJA8 GJB1 GJB5 GPR152 GPR42 GPR61 IFNLR1 KASH5 KIR3DL3 KLRC1 LAPTM4B LDLRAD1 LHFPL5 LSMEM2 MFF MGST2 MTIF3 NCAPH2 OPRD1 OPRM1 PACC1 PLPP5 PVR SCN3B SLC10A2 SPACA1 STOM TLCD4 TM4SF19 TMEM106C TMEM167B TMEM179B TMEM31 TMPRSS2 TMX2 TSPAN12	21 interacting genes: BDKRB1 CGRRF1 CTXN3 CYB561A3 EMP1 GJA8 GPX8 IFNAR1 IGFBP5 ISLR2 MTIF3 NAALADL2 NRG1 ODF4 PIP5K1C SCARB2 SLC22A1 SLC22A2 SLC29A2 TMEM86B TRARG1
Entrez ID		613212	55353
HPRD ID		18888	13960
Ensembl ID		ENSG00000205279	ENSG00000104341
Uniprot IDs		Q4LDR2	Q86VI4
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Plasma Membrane Protein Binding PH-gated Chloride Channel Activity Connexin Complex Gap Junction Channel Activity Gap Junction Immune Response-activating Cell Surface Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway G Protein-coupled Opioid Receptor Activity G Protein-coupled Receptor Activity Immune Response-regulating Cell Surface Receptor Signaling Pathway G Protein-coupled Opioid Receptor Signaling Pathway Immune System Process Immune Response-regulating Signaling Pathway	Pyrimidine-containing Compound Transmembrane Transport Neurotransmitter Transmembrane Transporter Activity Pyrimidine Nucleoside Transmembrane Transporter Activity Membrane Neurotransmitter Uptake Acetylcholine Transport Epinephrine Transport Spermidine Transmembrane Transport Putrescine Transport Spermidine Transmembrane Transporter Activity Putrescine Transmembrane Transporter Activity Acetylcholine Transmembrane Transporter Activity Purine-containing Compound Transmembrane Transport Spermidine Transport Thiamine Transmembrane Transporter Activity Thiamine Transport Quaternary Ammonium Group Transmembrane Transporter Activity Thiamine Transmembrane Transport Xenobiotic Transport Norepinephrine Uptake Xenobiotic Transport Across Blood-brain Barrier Toxin Transmembrane Transporter Activity Polyamine Transmembrane Transport Serotonin Uptake Norepinephrine Transport Prostaglandin Transmembrane Transporter Activity Monoamine Transmembrane Transporter Activity Organic Cation Transmembrane Transporter Activity Catecholamine Uptake Dopamine Uptake Azole Transmembrane Transport Serotonin Transport Quaternary Ammonium Group Transport Prostaglandin Transport Regulation Of Cell Growth Endosome To Plasma Membrane Protein Transport Transport Across Blood-brain Barrier Vitamin Transmembrane Transport Organic Anion Transmembrane Transporter Activity Neurotransmitter Transport Dopamine Transport Neurotransmitter Reuptake Cellular Detoxification Xenobiotic Transmembrane Transporter Activity Monoamine Transport Regulation Of Growth Import Into Cell Plasma Membrane Positive Regulation Of Peptidyl-tyrosine Autophosphorylation Apical Plasma Membrane
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