MTURN and TMEM239

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MTURN	TMEM239
Description		maturin, neural progenitor differentiation regulator homolog	transmembrane protein 239
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Regulation Of Signaling Negative Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Megakaryocyte Differentiation Positive Regulation Of JNK Cascade Positive Regulation Of ERK1 And ERK2 Cascade
Pathways
Drugs
Diseases
GWAS		Cadmium levels ( 26025379)	Estimated glomerular filtration rate ( 31451708) Pulse pressure ( 30224653) White matter integrity ( 23218918)
Interacting Genes		23 interacting genes: AP2M1 APP ARRDC1 DAZAP2 MKRN1 PLEKHB2 REL RNF41 RPS27A SH3RF1 SSX1 SUSD6 TMEM239 TNFRSF19 TP53BP2 TRAF6 TRIM38 TRIM39 TRIM5 TRIM8 UBA52 UBB UBC	68 interacting genes: AQP6 ATF7 CD79A CLDN20 CLRN1 COQ8A CREB3L1 CREB3L3 CXCL16 DARS2 DCUN1D1 EBP EMP1 FAM174A FAM209A FBXL19 FFAR2 FGD2 FKBP7 FTHL17 FXYD6 GJA8 GPR101 GPR151 GPR42 LENG1 LNX1 MIEF2 MPP1 MS4A3 MTIF3 MTURN MYG1 NTAQ1 OCIAD1 ODF4 OTULIN PDCD1LG2 PNKP POLI PSCA REEP2 RETREG3 S100B SCAND1 SCN3B SDCBP SENP2 SERINC2 SLC10A1 SLC10A6 SLC18A1 SLC34A2 SLC35H1 SLC71A2 SNX1 SNX2 SPG21 SSMEM1 SYT16 TBRG4 TIMMDC1 TMEM248 TMEM31 TMX2 TRHR UBASH3A USP5
Entrez ID		222166	100288797
HPRD ID		07635
Ensembl ID		ENSG00000180354	ENSG00000198326
Uniprot IDs		Q8N3F0	Q8WW34
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Protein Modification By Small Protein Conjugation Post-translational Protein Modification Protein Tag Activity Ubiquitin Protein Ligase Activity Protein Modification Process Endocytic Vesicle Membrane Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of Canonical NF-kappaB Signal Transduction Protein Polyubiquitination Ubiquitin Protein Ligase Binding Protein Metabolic Process Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of JNK Cascade Innate Immune Response Positive Regulation Of Signal Transduction Regulation Of Intracellular Signal Transduction Proteolysis Involved In Protein Catabolic Process Endosome Membrane Defense Response To Symbiont Regulation Of JNK Cascade Positive Regulation Of Cell Communication Defense Response To Other Organism Positive Regulation Of Signaling Canonical NF-kappaB Signal Transduction Modification-dependent Protein Catabolic Process Vesicle Protein Autoubiquitination Regulation Of Protein Catabolic Process Protein K63-linked Ubiquitination Mitochondrial Outer Membrane Regulation Of Signal Transduction Regulation Of MAPK Cascade Cytosol Suppression Of Viral Release By Host Identical Protein Binding Positive Regulation Of MAPK Cascade Macromolecule Catabolic Process Regulation Of Viral Entry Into Host Cell Protein Serine/threonine Kinase Binding Host-mediated Suppression Of Symbiont Invasion Response To Other Organism Zinc Ion Binding Transcription Coactivator Activity Low-density Lipoprotein Particle Receptor Binding Positive Regulation Of Receptor Internalization Regulation Of Cell Communication Regulation Of Signaling Regulation Of Lipopolysaccharide-mediated Signaling Pathway Proteolysis	Membrane Protein Binding Retromer, Tubulation Complex Leptin Receptor Binding Bile Acid:sodium Symporter Activity
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