F13B and F13A1

Number of citations of the paper that reports this interaction (PMID 8905624)
6

Data Source:
HPRD (in vitro)

		F13B	F13A1
Gene Name		coagulation factor XIII, B polypeptide	coagulation factor XIII, A1 polypeptide
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region	Extracellular Region Platelet Alpha Granule Lumen Blood Microparticle
	Molecular Function		Protein-glutamine Gamma-glutamyltransferase Activity Metal Ion Binding
	Biological Process	Blood Coagulation	Platelet Degranulation Blood Coagulation Peptide Cross-linking Platelet Activation
Pathways		Common Pathway Formation of Fibrin Clot (Clotting Cascade)	Common Pathway Response to elevated platelet cytosolic Ca2+ Platelet degranulation Platelet activation, signaling and aggregation Formation of Fibrin Clot (Clotting Cascade)
Drugs			1,2-Propanediol N-Acetyl-Serine
Diseases
GWAS		Age-related macular degeneration ( 23536807) Erectile dysfunction ( 22704111)	End-stage coagulation ( 23381943) MRI atrophy measures ( 21116278)
Protein-Protein Interactions		2 interactors: F13A1 FGG	13 interactors: ANXA7 CDKN1A F13B F2 FGA FGG FN1 NUDT21 PTK2 SERPINF2 SH3GL2 TK1 UFD1L
Entrez ID		2165	2162
HPRD ID		00605	00604
Ensembl ID		ENSG00000143278	ENSG00000124491
Uniprot IDs		P05160	P00488
PDB IDs			1EVU 1EX0 1F13 1FIE 1GGT 1GGU 1GGY 1QRK
Enriched GO Terms of Interacting Partners?		Platelet Degranulation Platelet Activation Exocytosis Blood Coagulation Hemostasis Secretion By Cell Regulation Of Body Fluid Levels Wound Healing Secretion Positive Regulation Of Heterotypic Cell-cell Adhesion Cell Activation Response To Wounding Negative Regulation Of Endothelial Cell Apoptotic Process Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Vasoconstriction Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Endothelial Cell Apoptotic Process Platelet Aggregation Peptide Cross-linking Vesicle-mediated Transport Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Vasoconstriction Positive Regulation Of Exocytosis Positive Regulation Of Peptide Hormone Secretion Positive Regulation Of Peptide Secretion Establishment Of Localization In Cell Protein Polymerization Positive Regulation Of Hormone Secretion Response To Calcium Ion Positive Regulation Of Cell-substrate Adhesion Cellular Localization Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Exocytosis	Hemostasis Regulation Of Body Fluid Levels Platelet Activation Blood Coagulation Wound Healing Response To Wounding Platelet Degranulation Regulation Of Cell Morphogenesis Regulation Of Cellular Component Organization Cell Activation Extracellular Matrix Organization Extracellular Structure Organization Acute-phase Response Regulation Of Cell Shape Positive Regulation Of Phosphorylation Negative Regulation Of Blood Coagulation Negative Regulation Of Coagulation Negative Regulation Of Wound Healing Protein Complex Assembly Acute Inflammatory Response Negative Regulation Of Fibrinolysis Response To Stress Positive Regulation Of Heterotypic Cell-cell Adhesion Regulation Of Blood Coagulation Regulation Of Fibrinolysis Response To Metal Ion Exocytosis Response To Calcium Ion Regulation Of Phosphorylation Regulation Of Cell-cell Adhesion Defense Response Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of Wound Healing Positive Regulation Of Intracellular Signal Transduction Regulation Of Cell Development Vesicle-mediated Transport Regulation Of Phosphorus Metabolic Process Negative Regulation Of Endothelial Cell Apoptotic Process Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Cell Morphogenesis Involved In Differentiation Positive Regulation Of Collagen Biosynthetic Process Regulation Of Cell Differentiation ERBB Signaling Pathway Positive Regulation Of Collagen Metabolic Process Response To Inorganic Substance Cell-matrix Adhesion Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Fibrinolysis Secretion By Cell
Tagcloud ?		1f a2hs allel alleles asia borderline city comparatively corresponds deviating dissimilarity distance east ethnic gc geographic jekaterinburg krakow moscow olomouc plg polymorphic poznan prague presumably regard szeged tf typed	10p13 17q21 5q15 6p24 australian british cl cleft crtl1 d1s58 d1s65 der excluded flank inheritance linkage lip lod multipoint palate rara syndromic theta unrelated van vim vws woude z
Tagcloud (Difference) ?		1f a2hs allel alleles asia borderline city comparatively corresponds deviating dissimilarity distance east ethnic gc geographic jekaterinburg krakow moscow olomouc plg polymorphic poznan prague presumably regard szeged tf typed	10p13 17q21 5q15 6p24 australian british cl cleft crtl1 d1s58 d1s65 der excluded flank inheritance linkage lip lod multipoint palate rara syndromic theta unrelated van vim vws woude z
Tagcloud (Intersection) ?