F13B

Description		coagulation factor XIII B chain
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Transferase Complex
	Molecular Function
	Biological Process	Blood Coagulation Hemostasis Blood Coagulation, Fibrin Clot Formation
Pathways		Common Pathway of Fibrin Clot Formation
Drugs		Zinc Catridecacog Thrombin Human thrombin Zinc acetate
Diseases		Factor XIII deficiency
GWAS		Age-related macular degeneration ( 23536807) Erectile dysfunction in type 1 diabetes ( 22704111) Lupus nephritis in systemic lupus erythematosus ( 24925725)
Novel Interacting Genes		1 novel interacting genes: PTPRC
Interacting Genes		2 interacting genes: F13A1 FGG
Entrez ID		2165
HPRD ID		00605
Ensembl ID		ENSG00000143278
Uniprot IDs		P05160
PDB IDs		8CMT 8CMU
Enriched GO Terms of Interacting Partners?		Blood Coagulation, Fibrin Clot Formation Protein Activation Cascade Platelet Alpha Granule Lumen Coagulation Blood Coagulation Hemostasis Blood Microparticle Plasma Membrane Raft Distribution Regulation Of Extrinsic Apoptotic Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Interleukin-4-mediated Signaling Pathway Positive Regulation Of Hematopoietic Stem Cell Migration Membrane Microdomain DN2 Thymocyte Differentiation Negative Regulation Of Cell Adhesion Involved In Substrate-bound Cell Migration Protein Maturation Extracellular Matrix Regulation Of Body Fluid Levels Protein-glutamine Gamma-glutamyltransferase Activity Positive Regulation Of Cell-cell Adhesion Signaling Receptor Binding Regulation Of Apoptotic Signaling Pathway Regulation Of ERK1 And ERK2 Cascade Plasminogen Activation Fibrinogen Complex External Side Of Plasma Membrane Negative Regulation Of T Cell Mediated Cytotoxicity Positive Regulation Of Gamma-delta T Cell Differentiation Positive Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Negative Regulation Of Microglial Cell Activation Positive Regulation Of Isotype Switching To IgG Isotypes Protein Tyrosine Kinase Inhibitor Activity Positive Regulation Of Gamma-delta T Cell Activation Membrane Raft Distribution Gamma-delta T Cell Differentiation Membrane Raft Localization Bleb Bone Marrow Development Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Positive Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Regulation Of Gamma-delta T Cell Differentiation Transferase Complex Positive Regulation Of Heterotypic Cell-cell Adhesion Positive Regulation Of MAPK Cascade Positive Thymic T Cell Selection Negative Thymic T Cell Selection Negative T Cell Selection Cell-cell Adhesion Positive Regulation Of Cell Adhesion Regulation Of Cell-cell Adhesion
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