ETF1 and GSPT2

Number of citations of the paper that reports this interaction (PMID 9712840)
25

Data Source:
BioGRID (affinity chromatography technology, two hybrid)
HPRD (in vivo, two hybrid)

		ETF1	GSPT2
Gene Name		eukaryotic translation termination factor 1	G1 to S phase transition 2
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol	Cytosol
	Molecular Function	RNA Binding Translation Release Factor Activity Protein Binding Translation Termination Factor Activity Translation Release Factor Activity, Codon Specific Ribosome Binding Poly(A) RNA Binding	GTPase Activity Protein Binding GTP Binding Poly(A) RNA Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Termination Regulation Of Translational Termination Protein Methylation Gene Expression Cellular Protein Metabolic Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Termination Cell Cycle Gene Expression Cellular Protein Metabolic Process
Pathways		Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Nonsense-Mediated Decay (NMD) Translation Eukaryotic Translation Termination Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Nonsense-Mediated Decay (NMD) Translation Eukaryotic Translation Termination Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: GSPT1 GSPT2 KEAP1 LIG4 PPP2CA	5 interactors: APP ETF1 GSPT1 PABPC1 UPF1
Entrez ID		2107	23708
HPRD ID		02616	02334
Ensembl ID		ENSG00000120705	ENSG00000189369
Uniprot IDs		B7Z7P8 P62495 Q96CG1	Q8IYD1
PDB IDs		1DT9 2HST 2KTU 2KTV 2LGT 2LLX 3E1Y	3KUJ
Enriched GO Terms of Interacting Partners?		Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process RNA Catabolic Process Cellular Macromolecule Catabolic Process RNA Metabolic Process Cell Cycle Aromatic Compound Catabolic Process MRNA Metabolic Process Catabolic Process DNA Ligation Involved In DNA Recombination Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Translational Termination Cellular Nitrogen Compound Metabolic Process Cellular Protein Complex Disassembly Nitrogen Compound Metabolic Process Protein Complex Disassembly Proteasomal Ubiquitin-independent Protein Catabolic Process Negative Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Lagging Strand Elongation Pro-B Cell Differentiation Establishment Of Integrated Proviral Latency Immunoglobulin V(D)J Recombination Mitotic Nuclear Envelope Reassembly Establishment Of Viral Latency Gene Expression T Cell Receptor V(D)J Recombination DNA Ligation Involved In DNA Repair Protein Heterotrimerization Cellular Macromolecule Biosynthetic Process Lymphoid Progenitor Cell Differentiation Nuclear Envelope Reassembly Macromolecule Biosynthetic Process Regulation Of Protein Catabolic Process Regulation Of Cell Differentiation DNA Ligation Nucleotide-excision Repair, DNA Gap Filling Cellular Response To Lithium Ion Negative Regulation Of Epithelial To Mesenchymal Transition In Utero Embryonic Development Single Strand Break Repair Double-strand Break Repair Via Nonhomologous End Joining Negative Regulation Of JAK-STAT Cascade Cellular Protein Metabolic Process Isotype Switching V(D)J Recombination DNA Strand Elongation Involved In DNA Replication Regulation Of Protein Autophosphorylation	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Metabolic Process Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process RNA Catabolic Process Regulation Of Translation Aromatic Compound Catabolic Process Posttranscriptional Regulation Of Gene Expression Regulation Of Translational Termination Cellular Macromolecule Catabolic Process MRNA Polyadenylation RNA Polyadenylation RNA Metabolic Process Gene Expression MRNA 3'-end Processing Catabolic Process RNA 3'-end Processing Translation Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Complex Disassembly Nucleobase-containing Compound Metabolic Process Translational Termination Regulation Of Protein Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Synaptic Growth At Neuromuscular Junction Cellular Nitrogen Compound Metabolic Process Protein Methylation Cellular Protein Complex Disassembly Collateral Sprouting In Absence Of Injury Nitrogen Compound Metabolic Process Protein Complex Disassembly Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Histone MRNA Catabolic Process Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Dosage Compensation By Inactivation Of X Chromosome Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Dosage Compensation Methylation MRNA Processing Positive Regulation Of MRNA 3'-end Processing Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Regulation Of MRNA 3'-end Processing Cellular Copper Ion Homeostasis
Tagcloud ?		adequate axillary classification classifier classifiers differentially enough eny2 fbx033 flj339115 flj33915 heterogeneity indicative infiltrated malignancy multiplex nodes osbpl parts predicting prognostic rps7 sets solely subdivides subgroup subtype usp38 validate
Tagcloud (Difference) ?		adequate axillary classification classifier classifiers differentially enough eny2 fbx033 flj339115 flj33915 heterogeneity indicative infiltrated malignancy multiplex nodes osbpl parts predicting prognostic rps7 sets solely subdivides subgroup subtype usp38 validate
Tagcloud (Intersection) ?