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GSPT2 and GSPT1
Number of citations of the paper that reports this interaction (PMID
9712840
)
25
Data Source:
HPRD
(in vivo, two hybrid)
GSPT2
GSPT1
Gene Name
G1 to S phase transition 2
G1 to S phase transition 1
Image
Gene Ontology Annotations
Cellular Component
Cytosol
Intracellular
Molecular Function
GTPase Activity
Protein Binding
GTP Binding
Poly(A) RNA Binding
Translation Release Factor Activity
GTPase Activity
Protein Binding
GTP Binding
Poly(A) RNA Binding
Biological Process
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Translation
Translational Termination
Cell Cycle
Gene Expression
Cellular Protein Metabolic Process
G1/S Transition Of Mitotic Cell Cycle
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Translational Termination
Protein Methylation
Pathways
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Nonsense-Mediated Decay (NMD)
Translation
Eukaryotic Translation Termination
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-Protein Interactions
5 interactors:
APP
ETF1
GSPT1
PABPC1
UPF1
10 interactors:
ATXN1
BIRC2
BIRC3
CDKN2A
ETF1
GSPT2
HINFP
PABPC1
PIK3R1
XIAP
Entrez ID
23708
2935
HPRD ID
02334
00753
Ensembl ID
ENSG00000189369
ENSG00000103342
Uniprot IDs
Q8IYD1
B2RCT6
P15170
Q7KZX8
PDB IDs
3KUJ
3E1Y
3KUI
Enriched GO Terms of Interacting Partners
?
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
MRNA Metabolic Process
Nuclear-transcribed MRNA Catabolic Process
MRNA Catabolic Process
RNA Catabolic Process
Regulation Of Translation
Aromatic Compound Catabolic Process
Posttranscriptional Regulation Of Gene Expression
Regulation Of Translational Termination
Cellular Macromolecule Catabolic Process
MRNA Polyadenylation
RNA Polyadenylation
RNA Metabolic Process
Gene Expression
MRNA 3'-end Processing
Catabolic Process
RNA 3'-end Processing
Translation
Regulation Of Cellular Protein Metabolic Process
Regulation Of Protein Complex Disassembly
Nucleobase-containing Compound Metabolic Process
Translational Termination
Regulation Of Protein Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Synaptic Growth At Neuromuscular Junction
Cellular Nitrogen Compound Metabolic Process
Protein Methylation
Cellular Protein Complex Disassembly
Collateral Sprouting In Absence Of Injury
Nitrogen Compound Metabolic Process
Protein Complex Disassembly
Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Collateral Sprouting
Axon Midline Choice Point Recognition
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Axon Choice Point Recognition
Neuron Remodeling
Histone MRNA Catabolic Process
Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening
Dosage Compensation By Inactivation Of X Chromosome
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Dosage Compensation
Methylation
MRNA Processing
Positive Regulation Of MRNA 3'-end Processing
Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Regulation Of MRNA 3'-end Processing
Cellular Copper Ion Homeostasis
Inhibition Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Regulation Of Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Positive Regulation Of Cellular Metabolic Process
Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Regulation Of Protein Ubiquitination
Regulation Of Cysteine-type Endopeptidase Activity
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity
Positive Regulation Of Metabolic Process
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Negative Regulation Of Necroptotic Process
Negative Regulation Of Necrotic Cell Death
Regulation Of Endopeptidase Activity
Regulation Of RIG-I Signaling Pathway
Regulation Of Necroptotic Process
Regulation Of Peptidase Activity
Positive Regulation Of Protein Ubiquitination
Apoptotic Process
Posttranscriptional Regulation Of Gene Expression
Nuclear-transcribed MRNA Catabolic Process
Programmed Cell Death
Regulation Of Necrotic Cell Death
MRNA Catabolic Process
Cell Death
Death
Cellular Protein Metabolic Process
Positive Regulation Of Cellular Protein Metabolic Process
Regulation Of Cellular Protein Metabolic Process
RNA Catabolic Process
Necroptotic Process
Protein Ubiquitination
RNA Metabolic Process
Positive Regulation Of Protein Metabolic Process
Protein Modification By Small Protein Conjugation
Positive Regulation Of Signal Transduction
Biosynthetic Process
Regulation Of Protein Metabolic Process
Regulation Of Immune System Process
Negative Regulation Of Cell-matrix Adhesion
Gene Expression
Regulation Of Proteolysis
Regulation Of Innate Immune Response
Regulation Of Toll-like Receptor Signaling Pathway
NIK/NF-kappaB Signaling
Programmed Necrotic Cell Death
Cellular Macromolecule Biosynthetic Process
Necrotic Cell Death
Negative Regulation Of Endopeptidase Activity
Regulation Of Apoptotic Process
Tagcloud
?
abnormally
blasts
bmmncs
chest
clustered
customized
ddit3
dimerization
ets
etv1
helicase
mad
max
microarray
pathogenetic
raeb
raebt
refractory
ribs
rnahp
rtc
semiquantitative
seventeen
tensin
thbs1
thrombocytopenia
thrombospondin
transcriptome
try
Tagcloud (Difference)
?
abnormally
blasts
bmmncs
chest
clustered
customized
ddit3
dimerization
ets
etv1
helicase
mad
max
microarray
pathogenetic
raeb
raebt
refractory
ribs
rnahp
rtc
semiquantitative
seventeen
tensin
thbs1
thrombocytopenia
thrombospondin
transcriptome
try
Tagcloud (Intersection)
?