GSPT2

Gene Name		G1 to S phase transition 2
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Gene Ontology Annotations	Cellular Component	Cytosol
	Molecular Function	GTPase Activity Protein Binding GTP Binding Poly(A) RNA Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Termination Cell Cycle Gene Expression Cellular Protein Metabolic Process
Pathways		Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Nonsense-Mediated Decay (NMD) Translation Eukaryotic Translation Termination Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-protein Interactions		5 interactors: APP ETF1 GSPT1 PABPC1 UPF1
Entrez ID		23708
HPRD ID		02334
Ensembl ID		ENSG00000189369
Uniprot IDs		Q8IYD1
PDB IDs		3KUJ
Enriched GO Terms of Interacting Partners?		Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Metabolic Process Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process RNA Catabolic Process Regulation Of Translation Aromatic Compound Catabolic Process Posttranscriptional Regulation Of Gene Expression Regulation Of Translational Termination Cellular Macromolecule Catabolic Process MRNA Polyadenylation RNA Polyadenylation RNA Metabolic Process Gene Expression MRNA 3'-end Processing Catabolic Process RNA 3'-end Processing Translation Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Complex Disassembly Nucleobase-containing Compound Metabolic Process Translational Termination Regulation Of Protein Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Synaptic Growth At Neuromuscular Junction Cellular Nitrogen Compound Metabolic Process Protein Methylation Cellular Protein Complex Disassembly Collateral Sprouting In Absence Of Injury Nitrogen Compound Metabolic Process Protein Complex Disassembly Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Histone MRNA Catabolic Process Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Dosage Compensation By Inactivation Of X Chromosome Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Dosage Compensation Methylation MRNA Processing Positive Regulation Of MRNA 3'-end Processing Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Regulation Of MRNA 3'-end Processing Cellular Copper Ion Homeostasis
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