ETF1

Gene Name		eukaryotic translation termination factor 1
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Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	RNA Binding Translation Release Factor Activity Protein Binding Translation Termination Factor Activity Translation Release Factor Activity, Codon Specific Ribosome Binding Poly(A) RNA Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Termination Regulation Of Translational Termination Protein Methylation Gene Expression Cellular Protein Metabolic Process
Pathways		Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Nonsense-Mediated Decay (NMD) Translation Eukaryotic Translation Termination Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-protein Interactions		5 interactors: GSPT1 GSPT2 KEAP1 LIG4 PPP2CA
Entrez ID		2107
HPRD ID		02616
Ensembl ID		ENSG00000120705
Uniprot IDs		B7Z7P8 P62495 Q96CG1
PDB IDs		1DT9 2HST 2KTU 2KTV 2LGT 2LLX 3E1Y
Enriched GO Terms of Interacting Partners?		Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process RNA Catabolic Process Cellular Macromolecule Catabolic Process RNA Metabolic Process Cell Cycle Aromatic Compound Catabolic Process MRNA Metabolic Process Catabolic Process DNA Ligation Involved In DNA Recombination Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Translational Termination Cellular Nitrogen Compound Metabolic Process Cellular Protein Complex Disassembly Nitrogen Compound Metabolic Process Protein Complex Disassembly Proteasomal Ubiquitin-independent Protein Catabolic Process Negative Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Lagging Strand Elongation Pro-B Cell Differentiation Establishment Of Integrated Proviral Latency Immunoglobulin V(D)J Recombination Mitotic Nuclear Envelope Reassembly Establishment Of Viral Latency Gene Expression T Cell Receptor V(D)J Recombination DNA Ligation Involved In DNA Repair Protein Heterotrimerization Cellular Macromolecule Biosynthetic Process Lymphoid Progenitor Cell Differentiation Nuclear Envelope Reassembly Macromolecule Biosynthetic Process Regulation Of Protein Catabolic Process Regulation Of Cell Differentiation DNA Ligation Nucleotide-excision Repair, DNA Gap Filling Cellular Response To Lithium Ion Negative Regulation Of Epithelial To Mesenchymal Transition In Utero Embryonic Development Single Strand Break Repair Double-strand Break Repair Via Nonhomologous End Joining Negative Regulation Of JAK-STAT Cascade Cellular Protein Metabolic Process Isotype Switching V(D)J Recombination DNA Strand Elongation Involved In DNA Replication Regulation Of Protein Autophosphorylation
Tagcloud ?		adequate axillary classification classifier classifiers differentially enough eny2 fbx033 flj339115 flj33915 heterogeneity indicative infiltrated malignancy multiplex nodes osbpl parts predicting prognostic rps7 sets solely subdivides subgroup subtype usp38 validate