MAPK14 and ESR1

Number of citations of the paper that reports this interaction (PMID 12138194)
46

Data Source:
HPRD (in vivo, in vitro)

		MAPK14	ESR1
Gene Name		mitogen-activated protein kinase 14	estrogen receptor 1
Image
Gene Ontology Annotations	Cellular Component	Spindle Pole Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol Extracellular Vesicular Exosome	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Plasma Membrane Membrane Integral Component Of Membrane Transcriptionally Active Chromatin
	Molecular Function	Protein Serine/threonine Kinase Activity MAP Kinase Activity MAP Kinase Kinase Activity Protein Binding ATP Binding NFAT Protein Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Core Promoter Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Steroid Hormone Receptor Activity Steroid Binding Protein Binding Beta-catenin Binding Transcription Factor Binding Zinc Ion Binding Enzyme Binding Nitric-oxide Synthase Regulator Activity Estrogen Receptor Activity Estrogen Response Element Binding Estrogen-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Identical Protein Binding
	Biological Process	DNA Damage Checkpoint Activation Of MAPK Activity Cell Morphogenesis Cartilage Condensation Angiogenesis Chondrocyte Differentiation Toll-like Receptor Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Glucose Metabolic Process Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Apoptotic Process Movement Of Cell Or Subcellular Component Chemotaxis Organelle Organization Mitochondrion Organization Signal Transduction Cell Surface Receptor Signaling Pathway Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Ras Protein Signal Transduction Skeletal Muscle Tissue Development Blood Coagulation Gene Expression Positive Regulation Of Myotube Differentiation Myoblast Differentiation Involved In Skeletal Muscle Regeneration Peptidyl-serine Phosphorylation Fatty Acid Oxidation Platelet Activation Osteoclast Differentiation Lipopolysaccharide-mediated Signaling Pathway Response To Muramyl Dipeptide Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Intracellular Signal Transduction TRIF-dependent Toll-like Receptor Signaling Pathway Cellular Response To Vascular Endothelial Growth Factor Stimulus P38MAPK Cascade Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Positive Regulation Of Protein Import Into Nucleus Muscle Cell Differentiation Signal Transduction In Response To DNA Damage Positive Regulation Of Blood Vessel Endothelial Cell Migration Innate Immune Response Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of Myoblast Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Vascular Endothelial Growth Factor Receptor Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Striated Muscle Cell Differentiation Positive Regulation Of Muscle Cell Differentiation Stress-activated MAPK Cascade 3'-UTR-mediated MRNA Stabilization Cellular Response To Lipopolysaccharide Cellular Response To Ionizing Radiation Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Brown Fat Cell Differentiation Stress-induced Premature Senescence Positive Regulation Of Myoblast Fusion Positive Regulation Of Reactive Oxygen Species Metabolic Process	Antral Ovarian Follicle Growth Epithelial Cell Development Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Signal Transduction Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Androgen Metabolic Process Male Gonad Development Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Phospholipase C Activity Intracellular Steroid Hormone Receptor Signaling Pathway Intracellular Estrogen Receptor Signaling Pathway Response To Estradiol Regulation Of Apoptotic Process Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Steroid Hormone Mediated Signaling Pathway Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Estrogen Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Fibroblast Proliferation Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Positive Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Uterus Development Vagina Development Prostate Epithelial Cord Elongation Prostate Epithelial Cord Arborization Involved In Prostate Glandular Acinus Morphogenesis Regulation Of Branching Involved In Prostate Gland Morphogenesis Mammary Gland Branching Involved In Pregnancy Mammary Gland Alveolus Development Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation Cellular Response To Estradiol Stimulus
Pathways		ADP signalling through P2Y purinoceptor 1 Cellular Senescence Toll Like Receptor TLR1:TLR2 Cascade Toll Like Receptor 5 (TLR5) Cascade NOD1/2 Signaling Pathway p38MAPK events MyD88 dependent cascade initiated on endosome Toll Like Receptor 9 (TLR9) Cascade ERK/MAPK targets activated TAK1 mediates p38 MAPK activation Regulation of mRNA stability by proteins that bind AU-rich elements CDO in myogenesis TRIF-mediated TLR3/TLR4 signaling Toll Like Receptor 2 (TLR2) Cascade Platelet homeostasis Activation of PPARGC1A (PGC-1alpha) by phosphorylation Myogenesis Signaling by VEGF Platelet sensitization by LDL Signalling to RAS Toll Like Receptor 4 (TLR4) Cascade Toll Like Receptor 3 (TLR3) Cascade Platelet activation, signaling and aggregation Signalling to ERKs Organelle biogenesis and maintenance Toll Like Receptor 7/8 (TLR7/8) Cascade Signal amplification VEGFA-VEGFR2 Pathway Toll Like Receptor TLR6:TLR2 Cascade Activated TLR4 signalling Activation of the AP-1 family of transcription factors MyD88 cascade initiated on plasma membrane MyD88:Mal cascade initiated on plasma membrane TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation Innate Immune System Signalling by NGF MAP kinase activation in TLR cascade NGF signalling via TRKA from the plasma membrane MyD88-independent cascade Mitochondrial biogenesis Toll-Like Receptors Cascades Toll Like Receptor 10 (TLR10) Cascade DSCAM interactions KSRP destabilizes mRNA Oxidative Stress Induced Senescence Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways ERK/MAPK targets MAPK targets/ Nuclear events mediated by MAP kinases Nuclear Events (kinase and transcription factor activation)	Nuclear signaling by ERBB4 Generic Transcription Pathway Nuclear Receptor transcription pathway Signaling by ERBB4
Drugs		4-[5-[2-(1-Phenyl-Ethylamino)-Pyrimidin-4-Yl]-1-Methyl-4-(3-Trifluoromethylphenyl)-1h-Imidazol-2-Yl]-Piperidine N-[(3z)-5-Tert-Butyl-2-Phenyl-1,2-Dihydro-3h-Pyrazol-3-Ylidene]-N\'-(4-Chlorophenyl)Urea 1-(2,6-Dichlorophenyl)-5-(2,4-Difluorophenyl)-7-Piperidin-4-Yl-3,4-Dihydroquinolin-2(1h)-One Inhibitor of P38 Kinase 6((S)-3-Benzylpiperazin-1-Yl)-3-(Naphthalen-2-Yl)-4-(Pyridin-4-Yl)Pyrazine 3-(4-Fluorophenyl)-1-Hydroxy-2-(Pyridin-4-Yl)-1h-Pyrrolo[3,2-B]Pyridine 1-(5-Tert-Butyl-2-Methyl-2h-Pyrazol-3-Yl)-3-(4-Chloro-Phenyl)-Urea 3-(Benzyloxy)Pyridin-2-Amine 1-(2,6-Dichlorophenyl)-5-(2,4-Difluorophenyl)-7-Piperazin-1-Yl-3,4-Dihydroquinazolin-2(1h)-One 4-[3-Methylsulfanylanilino]-6,7-Dimethoxyquinazoline 1-(5-Tert-Butyl-2-P-Tolyl-2h-Pyrazol-3-Yl)-3-[4-(2-Morpholin-4-Yl-Ethoxy)-Naphthalen-1-Yl]-Urea 2-Chlorophenol 4-(Fluorophenyl)-1-Cyclopropylmethyl-5-(2-Amino-4-Pyrimidinyl)Imidazole SB220025 4-(2-HYDROXYBENZYLAMINO)-N-(3-(4-FLUOROPHENOXY)PHENYL)PIPERIDINE-1-SULFONAMIDE Triazolopyridine 1-[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]-3-naphthalen-1-ylurea N-ethyl-4-{[5-(methoxycarbamoyl)-2-methylphenyl]amino}-5-methylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide N-[2-methyl-5-(methylcarbamoyl)phenyl]-2-{[(1R)-1-methylpropyl]amino}-1,3-thiazole-5-carboxamide 5-(2,6-dichlorophenyl)-2-[(2,4-difluorophenyl)sulfanyl]-6H-pyrimido[1,6-b]pyridazin-6-one N-cyclopropyl-4-methyl-3-[1-(2-methylphenyl)phthalazin-6-yl]benzamide 4-PHENOXY-N-(PYRIDIN-2-YLMETHYL)BENZAMIDE 4-[5-(3-IODO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-1H-IMIDAZOL-4-YL]-PYRIDINE N-cyclopropyl-2\',6-dimethyl-4\'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-3-carboxamide 4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE 4-{4-[(5-hydroxy-2-methylphenyl)amino]quinolin-7-yl}-1,3-thiazole-2-carbaldehyde N-(3-cyanophenyl)-2\'-methyl-5\'-(5-methyl-1,3,4-oxadiazol-2-yl)-4-biphenylcarboxamide N-(cyclopropylmethyl)-2\'-methyl-5\'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxamide N~3~-cyclopropyl-N~4~\'-(cyclopropylmethyl)-6-methylbiphenyl-3,4\'-dicarboxamide 3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-oxopyridin-1(2H)-yl}-N,4-dimethylbenzamide 2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine 2-{4-[5-(4-chlorophenyl)-4-pyrimidin-4-yl-1H-pyrazol-3-yl]piperidin-1-yl}-2-oxoethanol N-(3-TERT-BUTYL-1H-PYRAZOL-5-YL)-N\'-{4-CHLORO-3-[(PYRIDIN-3-YLOXY)METHYL]PHENYL}UREA N-[4-CHLORO-3-(PYRIDIN-3-YLOXYMETHYL)-PHENYL]-3-FLUORO- 3-FLUORO-5-MORPHOLIN-4-YL-N-[3-(2-PYRIDIN-4-YLETHYL)-1H-INDOL-5-YL]BENZAMIDE 3-FLUORO-N-1H-INDOL-5-YL-5-MORPHOLIN-4-YLBENZAMIDE 3-(1-NAPHTHYLMETHOXY)PYRIDIN-2-AMINE 3-(2-CHLOROPHENYL)-1-(2-{[(1S)-2-HYDROXY-1,2-DIMETHYLPROPYL]AMINO}PYRIMIDIN-4-YL)-1-(4-METHOXYPHENYL)UREA 8-(2-CHLOROPHENYLAMINO)-2-(2,6-DIFLUOROPHENYLAMINO)-9-ETHYL-9H-PURINE-1,7-DIIUM 2-(2,6-DIFLUOROPHENOXY)-N-(2-FLUOROPHENYL)-9-ISOPROPYL-9H-PURIN-8-AMINE N,4-dimethyl-3-[(1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)amino]benzamide N-cyclopropyl-3-{[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-4-yl]amino}-4-methylbenzamide N-cyclopropyl-4-methyl-3-{2-[(2-morpholin-4-ylethyl)amino]quinazolin-6-yl}benzamide 6-[4-(2-fluorophenyl)-1,3-oxazol-5-yl]-N-(1-methylethyl)-1,3-benzothiazol-2-amine 2-(ETHOXYMETHYL)-4-(4-FLUOROPHENYL)-3-[2-(2-HYDROXYPHENOXY)PYRIMIDIN-4-YL]ISOXAZOL-5(2H)-ONE [5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL][3-(PIPERIDIN-4-YLOXY)PHENYL]METHANONE [5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL](3-{[(2R)-2,3-DIHYDROXYPROPYL]OXY}PHENYL)METHANONE 4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE 4-(4-FLUOROPHENYL)-1-CYCLOROPROPYLMETHYL-5-(4-PYRIDYL)-IMIDAZOLE 3-FLUORO-5-MORPHOLIN-4-YL-N-[1-(2-PYRIDIN-4-YLETHYL)-1H-INDOL-6-YL]BENZAMIDE	Diethylstilbestrol Chlorotrianisene Conjugated Estrogens Etonogestrel Desogestrel Levonorgestrel Progesterone Raloxifene Toremifene Medroxyprogesterone Estrone Tamoxifen Estradiol Ethynodiol Diacetate Clomifene Dienestrol Fulvestrant Norgestimate Ethinyl Estradiol Melatonin Trilostane Naloxone Fluoxymesterone Estramustine Mestranol Danazol Allylestrenol Genistein Compound 19 Compound 18 Compound 4-D 1-[4-(Octahydro-Pyrido[1,2-a]Pyrazin-2-Yl)-Phenyl]-2-Phenyl-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol 2-Phenyl-1-[4-(2-Piperidin-1-Yl-Ethoxy)-Phenyl]-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol Estriol Estropipate Quinestrol Ospemifene 17-METHYL-17-ALPHA-DIHYDROEQUILENIN 4-(2-amino-1-methyl-1H-imidazo[4,5-b]pyridin-6-yl)phenol [5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-YL]ACETONITRILE 4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-8-METHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL 4-[(1S,2S,5S,9R)-5-(HYDROXYMETHYL)-8,9-DIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL 4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-6,8,9-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL (2R,3R,4S)-3-(4-HYDROXYPHENYL)-4-METHYL-2-[4-(2-PYRROLIDIN-1-YLETHOXY)PHENYL]CHROMAN-6-OL (3AS,4R,9BR)-2,2-DIFLUORO-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL (9ALPHA,13BETA,17BETA)-2-[(1Z)-BUT-1-EN-1-YL]ESTRA-1,3,5(10)-TRIENE-3,17-DIOL (9BETA,11ALPHA,13ALPHA,14BETA,17ALPHA)-11-(METHOXYMETHYL)ESTRA-1(10),2,4-TRIENE-3,17-DIOL 3-CHLORO-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL 3-ETHYL-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL dimethyl (1R,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL N-[(1R)-3-(4-HYDROXYPHENYL)-1-METHYLPROPYL]-2-(2-PHENYL-1H-INDOL-3-YL)ACETAMIDE (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-6-(METHOXYMETHYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL 4-[1-allyl-7-(trifluoromethyl)-1H-indazol-3-yl]benzene-1,3-diol 4-(6-HYDROXY-1H-INDAZOL-3-YL)BENZENE-1,3-DIOL DIETHYL (1R,2S,3R,4S)-5,6-BIS(4-HYDROXYPHENYL)-7-OXABICYCLO[2.2.1]HEPT-5-ENE-2,3-DICARBOXYLATE 2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE 4-[(1S,2R,5S)-4,4,8-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-9-OL RALOXIFENE CORE
Diseases
GWAS			Alcohol dependence ( 19581569) Bone mineral density ( 23437003) Bone mineral density (hip) ( 19079262 19801982 18445777) Bone mineral density (spine) ( 19079262 19801982 18445777) Breast cancer ( 22383897 21263130 19219042 23535729 23535733 20453838) Breast size ( 22747683) Chronic myeloid leukemia ( 21540461) Height ( 20881960 23563607) Obesity-related traits ( 23251661) Sudden cardiac arrest ( 21658281)
Protein-Protein Interactions		142 interactors: AES AIMP1 AKT1 ATF2 BAZ1B BCL2 BICD1 BMI1 CCDC14 CCDC97 CD4 CDC25A CDC25B CDC25C CDX2 CENPC CEP164 COPS5 CREB1 CSNK2A1 CSNK2A2 CSNK2B DDIT3 DDX26B DUSP1 DUSP10 DUSP16 DUSP2 DUSP22 DUSP4 DUSP7 DUSP9 DYRK1B EEA1 EEF1A1 EEF2K EGFR EIF4EBP1 ELK1 ELK3 ELMSAN1 EPB42 ESR1 ETV1 FKBP8 FLNA FUBP1 GADD45A GDF15 GMFB GORASP2 GRB2 HDAC3 HIVEP1 HNF4A HSF4 HTRA2 IRAK1 JDP2 JUN JUNB KARS KAT2B KMT2C KRT18 KRT8 LIMK1 MAFA MAP2K1 MAP2K3 MAP2K4 MAP2K6 MAP2K7 MAP3K10 MAP3K7 MAPK1 MAPK3 MAPK8 MAPKAPK2 MAPKAPK3 MAPKAPK5 MARS MAX MBP MEF2A MEF2C MEF2D MITF MKNK1 MKNK2 MOB3B MUC12 NCOA3 NFATC1 NFATC4 NKTR NUP153 PAK6 PHC2 PI4K2B PLA2G4A PLG PML PPARGC1A PTPN7 RBSN RELA RET ROBO1 RPL22 RPL41 RPS6KA4 RPS6KA5 SCN8A SH2D1A SHC1 SLC9A1 SMAD3 SMAD7 SMARCD3 SMEK1 SNAPIN SPAG9 SPTBN1 SQSTM1 SRPK1 SRSF5 STAT1 STAT4 STK39 SUPT20H TAB1 TCF20 TFCP2 TMEM63B TP53 TRAF6 UGT2B10 YY1AP1 ZFP36L1 ZNF142 ZNHIT1	266 interactors: ACTN4 AHR AKAP13 AKT1 AKT2 AR ARHGEF15 ARNT ATAD2 BAG1 BCAR1 BCAS2 BDNF BRCA1 BTF3 CALM1 CALM2 CALM3 CAV1 CBLL1 CCNC CCND1 CCNH CCNT1 CDC25B CDK2 CDK7 CDK8 CDKN1A CEBPA CEBPB CHD9 CHUK CITED1 COPS5 CREBBP CSNK2B CTNNB1 CUEDC2 CUL4B DAP3 DDX5 DDX54 DNTTIP2 DUT EGFR EHMT2 EIF3I EP300 ERBB2 ESR2 ESRRA FHL2 FKBP4 FKBP5 FLII FOXO1 FOXO3 FOXO4 GADD45B GADD45G GNAI1 GNAI2 GNAI3 GRB2 GRIP1 GTF2B GTF2H1 HDAC4 HDAC5 HDAC9 HEXIM1 HNF4A HSP90AA1 HSP90AB1 HSPA4 HSPA8 IGF1R ING1 ISL1 ITGB3BP JUN JUNB JUND KAT5 KDM5A KIF1A KLF5 KMT2D LCK LCOR LDB1 LINC00312 LRIF1 MAPK1 MAPK14 MAPK3 MDM2 MED1 MED10 MED12 MED13 MED14 MED16 MED17 MED20 MED21 MED23 MED24 MED25 MED6 MED7 MEN1 MGMT MKNK2 MMS19 MNAT1 MPG MSH2 MTA1 MTA2 MTA3 MTCH2 MUC1 MVP NCOA1 NCOA2 NCOA3 NCOA4 NCOA6 NCOA7 NCOR1 NCOR2 NELFB NFKB1 NPPA NR0B1 NR0B2 NR1H4 NR2C1 NR2C2 NR2F1 NR2F6 NRIP1 NSD1 OTUB1 PAGR1 PAK1 PAK6 PELP1 PGC PGR PHB PHB2 PIAS1 PIAS2 PIAS3 PIK3R1 PIK3R3 PNRC2 POLR1B POLR2D POU2F1 POU2F2 POU4F1 POU4F2 PPARG PPARGC1A PPARGC1B PPID PRDM2 PRKACA PRMT1 PRMT2 PRPF6 PSMC5 PTEN PTGES3 PTMA PTPN1 PTPN6 RAC3 RANBP9 RARA RBBP4 RBBP7 RBFOX2 RBM23 RBM39 RELA REXO4 RFX4 RGS3 RLIM RNF14 RNF4 RPS6KA1 RPS6KA3 RXRA SAFB SAFB2 SETD7 SF1 SHC1 SKIL SKP2 SLC30A9 SMAD2 SMAD3 SMAD4 SMARCA2 SMARCA4 SMARCD1 SMARCD3 SMARCE1 SMURF1 SMYD2 SOS1 SP1 SP3 SRA1 SRC SREBF1 STAT5A STRN STUB1 SUMO1 SUV39H1 SUV420H1 SVIL TAB2 TADA3 TAF10 TAF1A TAF1B TAF2 TAP1 TBP TCF20 TDG THRA THRB TNFRSF14 TP53 TRAM1 TRIM24 TRIM25 TRIM28 TRIM59 TRIP4 TRRAP TSC2 TUBA1B TUBB UBE2I UIMC1 USF1 VAV3 WHSC1 WIPI1 XBP1 YWHAH YWHAQ ZBTB16 ZBTB17 ZNF398
Entrez ID		1432	2099
HPRD ID		02619	00589
Ensembl ID		ENSG00000112062	ENSG00000091831
Uniprot IDs		L7RSM2 Q16539	G4XH65 P03372 Q9UBT1
PDB IDs		1A9U 1BL6 1BL7 1BMK 1DI9 1IAN 1KV1 1KV2 1M7Q 1OUK 1OUY 1OVE 1OZ1 1R39 1R3C 1W7H 1W82 1W83 1W84 1WBN 1WBO 1WBS 1WBT 1WBV 1WBW 1WFC 1YQJ 1ZYJ 1ZZ2 1ZZL 2BAJ 2BAK 2BAL 2BAQ 2FSL 2FSM 2FSO 2FST 2GFS 2I0H 2LGC 2NPQ 2OKR 2ONL 2QD9 2RG5 2RG6 2Y8O 2YIS 2YIW 2YIX 2ZAZ 2ZB0 2ZB1 3BV2 3BV3 3BX5 3C5U 3CTQ 3D7Z 3D83 3DS6 3DT1 3E92 3E93 3FC1 3FI4 3FKL 3FKN 3FKO 3FL4 3FLN 3FLQ 3FLS 3FLW 3FLY 3FLZ 3FMH 3FMJ 3FMK 3FML 3FMM 3FMN 3FSF 3FSK 3GC7 3GCP 3GCQ 3GCS 3GCU 3GCV 3GFE 3GI3 3HA8 3HEC 3HEG 3HL7 3HLL 3HP2 3HP5 3HRB 3HUB 3HUC 3HV3 3HV4 3HV5 3HV6 3HV7 3HVC 3IPH 3ITZ 3IW5 3IW6 3IW7 3IW8 3K3I 3K3J 3KF7 3KQ7 3L8S 3L8X 3LFA 3LFB 3LFC 3LFD 3LFE 3LFF 3LHJ 3MGY 3MH0 3MH1 3MH2 3MH3 3MPA 3MPT 3MVL 3MVM 3MW1 3NEW 3NNU 3NNV 3NNW 3NNX 3NWW 3O8P 3O8T 3O8U 3OBG 3OBJ 3OC1 3OCG 3OD6 3ODY 3ODZ 3OEF 3PG3 3QUD 3QUE 3RIN 3ROC 3S3I 3S4Q 3U8W 3UVP 3UVQ 3UVR 3ZS5 3ZSG 3ZSH 3ZSI 3ZYA 4A9Y 4AA0 4AA4 4AA5 4AAC 4DLI 4DLJ 4E5A 4E5B 4E6A 4E6C 4E8A 4EH2 4EH3 4EH4 4EH5 4EH6 4EH7 4EH8 4EH9 4EHV 4EWQ 4F9W 4F9Y 4FA2 4GEO 4KIN 4KIP 4KIQ	1A52 1AKF 1ERE 1ERR 1G50 1GWQ 1GWR 1HCP 1HCQ 1L2I 1PCG 1QKT 1QKU 1R5K 1SJ0 1UOM 1X7E 1X7R 1XP1 1XP6 1XP9 1XPC 1XQC 1YIM 1YIN 1ZKY 2AYR 2B1V 2B1Z 2B23 2BJ4 2FAI 2G44 2G5O 2I0J 2IOG 2IOK 2JF9 2JFA 2LLO 2LLQ 2OCF 2OUZ 2P15 2POG 2Q6J 2Q70 2QA6 2QA8 2QAB 2QE4 2QGT 2QGW 2QH6 2QR9 2QSE 2QXM 2QXS 2QZO 2R6W 2R6Y 2YAT 2YJA 3CBM 3CBO 3CBP 3DT3 3ERD 3ERT 3HLV 3HM1 3L03 3OS8 3OS9 3OSA 3Q95 3Q97 3UU7 3UUA 3UUC 3UUD 4AA6 4DMA 4IU7 4IUI 4IV2 4IV4 4IVW 4IVY 4IW6 4IW8 4IWC 4IWF 4JC3 4JDD
Enriched GO Terms of Interacting Partners?		Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Toll-like Receptor 4 Signaling Pathway MAPK Cascade Signal Transduction By Phosphorylation Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Toll-like Receptor Signaling Pathway Regulation Of Protein Phosphorylation Intracellular Signal Transduction Regulation Of Metabolic Process Cellular Response To Organic Substance Cellular Metabolic Process Regulation Of Phosphorylation Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Regulation Of Phosphorus Metabolic Process Positive Regulation Of Metabolic Process Activation Of Innate Immune Response Positive Regulation Of Innate Immune Response Regulation Of Innate Immune Response Positive Regulation Of Macromolecule Biosynthetic Process Developmental Process Cellular Response To Growth Factor Stimulus Response To Organic Substance Enzyme Linked Receptor Protein Signaling Pathway Cell Communication Response To Growth Factor Signaling Positive Regulation Of Cellular Biosynthetic Process Immune Response-regulating Signaling Pathway Positive Regulation Of Transcription, DNA-templated Phosphorylation Regulation Of MAP Kinase Activity Response To Stress Regulation Of Protein Kinase Activity Regulation Of Signal Transduction Anatomical Structure Development Phosphate-containing Compound Metabolic Process	Regulation Of Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of RNA Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Gene Expression RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Intracellular Receptor Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process DNA-templated Transcription, Initiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Biosynthetic Process Nitrogen Compound Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Intracellular Steroid Hormone Receptor Signaling Pathway Negative Regulation Of Gene Expression Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Regulation Of Cellular Process Response To Hormone Response To Organic Substance Cellular Metabolic Process Cellular Response To Organic Substance Negative Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Stimulus Cellular Response To Hormone Stimulus Androgen Receptor Signaling Pathway Signal Transduction Response To Stimulus Developmental Process
Tagcloud ?		acta2 cdh1 cdkn1a cldn1 cldn4 cldn7 ctnnb1 fn1 krt19 mapk3 mki67 mmp2 mmp9 muc5ac muc6 nes pdac pdacs ptgs2 rps6 rps6kb1 smad4 stains surprising synchronous tgfb1 tgfbr1 vim	analyzing brca1 carcinogenic changed characters coactivator concordant conduct differentiationassociated discovered downloaded e2 enrichment estradiol go gses9623 gsm986085 gsm986087 guidance macs mcf7 omnibus ontology p300bound p300regulated participated peakcalling software theoretical
Tagcloud (Difference) ?		acta2 cdh1 cdkn1a cldn1 cldn4 cldn7 ctnnb1 fn1 krt19 mapk3 mki67 mmp2 mmp9 muc5ac muc6 nes pdac pdacs ptgs2 rps6 rps6kb1 smad4 stains surprising synchronous tgfb1 tgfbr1 vim	analyzing brca1 carcinogenic changed characters coactivator concordant conduct differentiationassociated discovered downloaded e2 enrichment estradiol go gses9623 gsm986085 gsm986087 guidance macs mcf7 omnibus ontology p300bound p300regulated participated peakcalling software theoretical
Tagcloud (Intersection) ?