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TRMT2B
Description
tRNA methyltransferase 2B
Image
No pdb structure
GO Annotations
Cellular Component
Mitochondrion
Mitochondrial Matrix
Molecular Function
Protein Binding
Methyltransferase Activity
RNA Methyltransferase Activity
Transferase Activity
TRNA (uracil(54)-C5)-methyltransferase Activity, S-adenosyl Methionine-dependent
RRNA (uridine-C5-)-methyltransferase Activity
Biological Process
RRNA Processing
RNA Processing
TRNA Processing
RRNA Methylation
Methylation
Pathways
Drugs
Diseases
GWAS
Interacting Genes
3 interacting genes:
AKT1
ERCC1
PTPN11
Entrez ID
79979
HPRD ID
06520
Ensembl ID
ENSG00000188917
Uniprot IDs
Q96GJ1
PDB IDs
Enriched GO Terms of Interacting Partners
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Insulin-like Growth Factor Receptor Signaling Pathway
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Cellular Response To Epidermal Growth Factor Stimulus
Positive Regulation Of D-glucose Import
Positive Regulation Of D-glucose Transmembrane Transport
T Cell Costimulation
Negative Regulation Of Lipid Transport
Response To Epidermal Growth Factor
Regulation Of D-glucose Import
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Regulation Of D-glucose Transmembrane Transport
Enzyme-linked Receptor Protein Signaling Pathway
Multicellular Organism Growth
Developmental Process Involved In Reproduction
Positive Regulation Of Mitotic Cell Cycle
Ameboidal-type Cell Migration
Cell Development
Regulation Of TRNA Methylation
Negative Regulation Of Cortisol Secretion
Negative Regulation Of Growth Hormone Secretion
Regulation Of Lipid Transport
Response To UV
Negative Regulation Of Leukocyte Cell-cell Adhesion
Leukocyte Activation Involved In Immune Response
Cell Activation Involved In Immune Response
Carbohydrate Homeostasis
Positive Regulation Of Protein Localization To Endoplasmic Reticulum
Germ Cell Development
Glucose Homeostasis
Negative Regulation Of Cell-cell Adhesion
Response To Insulin-like Growth Factor Stimulus
Reproductive Process
Mammalian Oogenesis Stage
Negative Regulation Of Protein Localization
TRNA (guanine-N7)-methylation
Cellular Response To Rapamycin
Negative Regulation Of Hydrogen Peroxide-induced Neuron Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Protein Localization To Lysosome
Positive Regulation Of Endodeoxyribonuclease Activity
Telomeric DNA-containing Double Minutes Formation
Hemopoiesis
Nucleotide-excision Repair Factor 1 Complex
Negative Regulation Of Protection From Non-homologous End Joining At Telomere
Reproductive Structure Development
Intestinal Epithelial Cell Migration
Cerebellar Cortex Formation
Animal Organ Development
Negative Regulation Of Long-chain Fatty Acid Import Across Plasma Membrane
TORC2 Complex Binding
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