KIAA2018 and NFYC

Number of citations of the paper that reports this interaction (PMID 20936779)
48

Data Source:
BioGRID (two hybrid)

		KIAA2018	NFYC
Gene Name		KIAA2018	nuclear transcription factor Y, gamma
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Membrane	Nucleus Nucleoplasm CCAAT-binding Factor Complex Protein-DNA Complex
	Molecular Function	DNA Binding Mannosyl-oligosaccharide 1,2-alpha-mannosidase Activity Calcium Ion Binding Protein Dimerization Activity	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Transcription Factor Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity
	Biological Process	Metabolic Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Protein Folding Cellular Lipid Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Transcription, DNA-templated
Pathways			PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins ATF4 activates genes ATF6-alpha activates chaperone genes Regulation of cholesterol biosynthesis by SREBP (SREBF) Activation of gene expression by SREBF (SREBP) Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) PERK regulates gene expression ATF6-alpha activates chaperones Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS		Bone mineral density ( 22504420) Prostate cancer ( 23535732)	Platelet counts ( 21507922)
Protein-Protein Interactions		1 interactors: NFYC	27 interactors: ADNP2 ARID2 ATF6 ATF6B CIC CSN2 DR1 DST GAPDH GLTSCR1 GLTSCR1L KIAA2018 LMO4 MYC NFYA NFYB POGZ SMAD2 SMAD3 SNX2 SP1 SREBF2 TAF11 TAF12 TAF6 TBP ZDHHC17
Entrez ID		205717	4802
HPRD ID		13912	05633
Ensembl ID		ENSG00000176542	ENSG00000066136
Uniprot IDs		Q68DE3	Q13952
PDB IDs			1N1J 4AWL
Enriched GO Terms of Interacting Partners?			Transcription, DNA-templated RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process RNA Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Gene Expression Biosynthetic Process Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Regulation Of Metabolic Process DNA-templated Transcription, Elongation Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of RNA Biosynthetic Process Primary MiRNA Processing Viral Process Regulation Of Nodal Signaling Pathway Cellular Metabolic Process SMAD Protein Complex Assembly Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Paraxial Mesoderm Morphogenesis Positive Regulation By Host Of Viral Transcription Positive Regulation Of Metabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Tagcloud ?		15q25 5p15 6p21 adca bag6 ebln2 entirely exome germline gon4l gwas nelfe nop58 players polygenic predispose predisposition rbmx reproducible sib sibling sibs smokers spen taf1b tceb3c truncating wisp3 znf311	associates attempt blastocyst cdc25a cdc42 egg embryonal esg1 exist forced icm immediately immunoprecipitated inner kh notion nr5a2 oct3 overlap pluripotency polar pou5f1 preimplantation supporting te transcript transcriptase transcripts trophectoderm
Tagcloud (Difference) ?		15q25 5p15 6p21 adca bag6 ebln2 entirely exome germline gon4l gwas nelfe nop58 players polygenic predispose predisposition rbmx reproducible sib sibling sibs smokers spen taf1b tceb3c truncating wisp3 znf311	associates attempt blastocyst cdc25a cdc42 egg embryonal esg1 exist forced icm immediately immunoprecipitated inner kh notion nr5a2 oct3 overlap pluripotency polar pou5f1 preimplantation supporting te transcript transcriptase transcripts trophectoderm
Tagcloud (Intersection) ?