ENSA and RAP2A

Number of citations of the paper that reports this interaction (PubMedID 18624398)
0

Data Source:
BioGRID (two hybrid)

		ENSA	RAP2A
Description		endosulfine alpha	RAP2A, member of RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm	Lysosome Endosome Golgi Apparatus Cytosol Plasma Membrane Endomembrane System Membrane Midbody Cytoplasmic Vesicle Membrane Lamellipodium Membrane Endolysosome Cell Projection Synapse Recycling Endosome Recycling Endosome Membrane Synaptic Membrane Bounding Membrane Of Organelle Schaffer Collateral - CA1 Synapse
	Molecular Function	Protein Phosphatase Inhibitor Activity Signaling Receptor Binding Protein Binding Ion Channel Inhibitor Activity Phosphatase Inhibitor Activity Potassium Channel Inhibitor Activity Protein Phosphatase Regulator Activity Protein Phosphatase 2A Binding	Nucleotide Binding Magnesium Ion Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Response To Nutrient Regulation Of Insulin Secretion Cell Division	Signal Transduction Intracellular Protein Localization Actin Cytoskeleton Organization Positive Regulation Of Cell Migration Negative Regulation Of Cell Migration Rap Protein Signal Transduction Establishment Of Protein Localization Regulation Of JNK Cascade Regulation Of Dendrite Morphogenesis Regulation Of Synapse Assembly Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Positive Regulation Of Microvillus Assembly
Pathways		MASTL Facilitates Mitotic Progression MASTL Facilitates Mitotic Progression
Drugs			Guanosine-5'-Triphosphate Guanosine-5'-Diphosphate
Diseases
GWAS		Albumin-globulin ratio ( 29403010) Chronotype ( 30696823) Coffee consumption ( 31959922) Eosinophil count ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Lung function (FEV1) ( 26635082) Lung function (FVC) ( 26635082) Mean corpuscular volume ( 32888494) Monocyte count ( 29403010 27863252 32888494) Monocyte percentage of white cells ( 27863252 32888494) Morning person ( 30696823) Neutrophil percentage of granulocytes ( 27863252) Non-albumin protein levels ( 29403010) Pericardial adipose tissue adjusted for height and weight ( 27918534) Refractive error ( 32231278) Rhegmatogenous retinal detachment ( 23585552) Sum eosinophil basophil counts ( 27863252) Urate levels ( 31578528)	Gut microbiota (bacterial taxa) ( 27723756) Peripheral artery disease ( 26488411)
Interacting Genes		11 interacting genes: ABCC8 ACD ARIH2 DNMT1 ENO2 KCTD15 POT1 PSEN1 RAP2A SNCA SRPK2	32 interacting genes: ACVR1 AFDN ARHGAP29 BMPR1B EEF1A1 ENSA FKBP2 FNTB FTL GABARAPL2 GRIN1 GRIN2D MAP4K4 NEDD4 PLG RAB40B RAF1 RALGDS RAPGEF3 RAPGEF4 RAPGEF5 RAPGEF6 RASIP1 RASSF5 RGS14 RRP9 RUNDC3A SERPINA1 SMAD1 TGFBR1 TM7SF2 TNIK
Entrez ID		2029	5911
HPRD ID		11927	01547
Ensembl ID		ENSG00000143420	ENSG00000125249
Uniprot IDs		O43768	P10114
PDB IDs			1KAO 2RAP 3RAP
Enriched GO Terms of Interacting Partners?		Magnesium Ion Binding Synaptic Membrane Telomerase Inhibitor Activity Shelterin Complex Telomere Assembly Establishment Of Protein Localization To Telomere Nuclear Telomere Cap Complex Telomere Capping Positive Regulation Of Receptor Recycling Positive Regulation Of Cellular Component Organization Negative Regulation Of Cellular Component Organization Growth Cone Negative Regulation Of Nervous System Development Negative Regulation Of Neurogenesis Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Via Telomerase Regulation Of Receptor Recycling RNA-templated DNA Biosynthetic Process Telomere Maintenance Via Telomere Lengthening Telomeric DNA Binding Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Cell Cortex L-glutamate Import Regulation Of Protein Localization Nuclear Outer Membrane Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Telomere Maintenance Neurotransmitter Secretion Regulation Of Establishment Of Protein Localization Regulation Of Telomere Maintenance Via Telomerase Regulation Of Cellular Component Organization Acidic Amino Acid Transport Regulation Of Neuron Apoptotic Process Organelle Organization Segmentation Negative Regulation Of Core Promoter Binding Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Positive Regulation Of Uterine Smooth Muscle Relaxation Negative Regulation Of Neuroblast Migration Regulation Of Telomere Maintenance Via Telomere Lengthening Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Negative Regulation Of Cell Development Regulation Of Dendrite Morphogenesis	Intracellular Signaling Cassette Signal Transduction Transforming Growth Factor Beta Receptor Activity, Type I Intracellular Signal Transduction Ras Protein Signal Transduction Small GTPase-mediated Signal Transduction Transmembrane Receptor Protein Serine/threonine Kinase Activity Protein Serine/threonine Kinase Activity Positive Regulation Of Cell Communication Positive Regulation Of Signaling GTPase Regulator Activity Regulation Of Cell Communication Regulation Of Signaling Positive Regulation Of Microvillus Assembly Protein Kinase Activity Establishment Of Endothelial Barrier Activin Receptor Complex Activin Receptor Activity, Type I NMDA Glutamate Receptor Activity Glutamate Binding Endothelial Cell Development Guanyl-nucleotide Exchange Factor Activity BMP Receptor Activity Positive Regulation Of Cardiac Epithelial To Mesenchymal Transition SMAD Binding NMDA Selective Glutamate Receptor Complex Glutamate-gated Calcium Ion Channel Activity Positive Regulation Of Signal Transduction Kinase Activity Potassium Channel Inhibitor Activity Excitatory Chemical Synaptic Transmission Regulation Of Microvillus Assembly Activin Binding Cellular Response To Growth Factor Stimulus Enzyme-linked Receptor Protein Signaling Pathway Plasma Membrane Regulation Of Type B Pancreatic Cell Proliferation Regulation Of Intracellular Signal Transduction Protein Binding Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Signal Transduction Nucleotide Binding Regulation Of Insulin Secretion Response To Growth Factor Establishment Of Endothelial Intestinal Barrier Positive Regulation Of Osteoblast Differentiation Regulation Of Cartilage Development Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway I-SMAD Binding Positive Regulation Of Cellular Component Biogenesis
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