TIGIT and PLLP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TIGIT	PLLP
Description		T cell immunoreceptor with Ig and ITIM domains	plasmolipin
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Membrane	Golgi Apparatus Plasma Membrane Membrane Apical Plasma Membrane Myelin Sheath Compact Myelin Membrane Raft
	Molecular Function	Signaling Receptor Binding Protein Binding Signaling Receptor Activity Identical Protein Binding	Protein Binding Structural Constituent Of Myelin Sheath Identical Protein Binding
	Biological Process	Negative Regulation Of Interleukin-12 Production Positive Regulation Of Interleukin-10 Production Natural Killer Cell Mediated Cytotoxicity Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Negative Regulation Of T Cell Activation	Monoatomic Ion Transport Regulation Of Endocytosis Myelin Assembly Myelination Regulation Of Transcytosis
Pathways
Drugs
Diseases
GWAS			HDL cholesterol levels ( 32203549) Hip circumference adjusted for BMI ( 28552196) Sleep duration ( 23728906) Systemic lupus erythematosus ( 28714469)
Interacting Genes		6 interacting genes: MAL NECTIN2 NECTIN3 NECTIN4 PLLP PVR	57 interacting genes: AQP6 BCL2L13 BIK CCR2 CD164L2 CLDN14 CLEC12B CLEC2D CRB3 CREB3 CYB5R3 CYSRT1 DRD2 EBP ELOVL4 ERGIC3 FAM174A FAM209A FKBP7 FNDC9 FRS3 GOLT1A GPR35 GPX8 GRN HOXA1 HTR2B KCNJ6 KRT34 KRTAP10-1 KRTAP9-2 LHFPL5 LMNA MC4R MFF MMP14 MS4A12 OPRL1 PACC1 PGRMC2 PTAFR RNF122 SAR1A SLC10A6 SLC35H1 STING1 SYPL2 TIGIT TMEM14B TMEM167B TMEM174 TMPPE TMPRSS2 TNFSF14 TRIM59 VMA21 ZDHHC15
Entrez ID		201633	51090
HPRD ID		08804	11854
Ensembl ID		ENSG00000181847	ENSG00000102934
Uniprot IDs		Q495A1	Q9Y342
PDB IDs		3Q0H 3RQ3 3UCR 3UDW 5V52 7VYT 8JEL 8JEN 8JEO 8SZY
Enriched GO Terms of Interacting Partners?		Cell Adhesion Mediator Activity Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Symbiont Entry Into Host Cell Susceptibility To T Cell Mediated Cytotoxicity Susceptibility To Natural Killer Cell Mediated Cytotoxicity Biological Process Involved In Interaction With Host Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Immune Response To Tumor Cell Regulation Of Natural Killer Cell Mediated Immunity Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Structural Constituent Of Myelin Sheath Virus Receptor Activity Cell Adhesion Molecule Binding Negative Regulation Of Innate Immune Response Regulation Of Leukocyte Mediated Cytotoxicity Receptor Ligand Activity Positive Regulation Of Immune Response To Tumor Cell Cell-cell Contact Zone Apical Junction Complex Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Response To Tumor Cell Cell-cell Adhesion Adherens Junction Positive Regulation Of T Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Lymphocyte Mediated Immunity Establishment Of Protein Localization To Membrane Negative Regulation Of Immune Response Natural Killer Cell Mediated Cytotoxicity Natural Killer Cell Mediated Immunity Regulation Of T Cell Mediated Cytotoxicity Protein Insertion Into Plasma Membrane Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane Coreceptor-mediated Virion Attachment To Host Cell Cellular Anatomical Entity Morphogenesis Negative Regulation Of Defense Response Membrane Positive Regulation Of Leukocyte Mediated Cytotoxicity Positive Regulation Of Cell Killing Positive Regulation Of T Cell Mediated Immunity Leukocyte Mediated Cytotoxicity Sperm Mitochondrion Organization Lactosylceramide Biosynthetic Process Regulation Of Transcytosis TRNA-guanosine(34) Queuine Transglycosylase Activity TRNA Wobble Guanine Modification TRNA-guanine Transglycosylase Complex	Membrane Endoplasmic Reticulum PH-gated Chloride Channel Activity Protein Binding Regulation Of Behavior Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?