PLLP and CLDN14

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PLLP	CLDN14
Description		plasmolipin	claudin 14
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Plasma Membrane Membrane Apical Plasma Membrane Myelin Sheath Compact Myelin Membrane Raft	Endoplasmic Reticulum Plasma Membrane Bicellular Tight Junction Membrane Anchoring Junction
	Molecular Function	Protein Binding Structural Constituent Of Myelin Sheath Identical Protein Binding	Structural Molecule Activity Protein Binding Identical Protein Binding
	Biological Process	Monoatomic Ion Transport Regulation Of Endocytosis Myelin Assembly Myelination Regulation Of Transcytosis	Cell Adhesion Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Protein-containing Complex Assembly Bicellular Tight Junction Assembly
Pathways			Tight junction interactions
Drugs
Diseases			Deafness, autosomal recessive
GWAS		HDL cholesterol levels ( 32203549) Hip circumference adjusted for BMI ( 28552196) Sleep duration ( 23728906) Systemic lupus erythematosus ( 28714469)	Blood urea nitrogen levels ( 31152163) Bone mineral density ( 24249740) Estimated glomerular filtration rate ( 31015462 31152163) Femur bone mineral density x serum urate levels interaction ( 34046847) Glomerular filtration rate ( 29403010) Heel bone mineral density ( 30598549) Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Kidney stones ( 26272126 31729369 19561606) Obsessive-compulsive traits ( 33531474) Red blood cell count ( 32888494) Serum parathyroid hormone levels ( 27927781) Urate levels ( 31578528) Urinary electrolytes (magnesium/calcium ratio) ( 27915449) Urolithiasis ( 30975718)
Interacting Genes		57 interacting genes: AQP6 BCL2L13 BIK CCR2 CD164L2 CLDN14 CLEC12B CLEC2D CRB3 CREB3 CYB5R3 CYSRT1 DRD2 EBP ELOVL4 ERGIC3 FAM174A FAM209A FKBP7 FNDC9 FRS3 GOLT1A GPR35 GPX8 GRN HOXA1 HTR2B KCNJ6 KRT34 KRTAP10-1 KRTAP9-2 LHFPL5 LMNA MC4R MFF MMP14 MS4A12 OPRL1 PACC1 PGRMC2 PTAFR RNF122 SAR1A SLC10A6 SLC35H1 STING1 SYPL2 TIGIT TMEM14B TMEM167B TMEM174 TMPPE TMPRSS2 TNFSF14 TRIM59 VMA21 ZDHHC15	4 interacting genes: CTXN3 MAL PLEKHA1 PLLP
Entrez ID		51090	23562
HPRD ID		11854	05727
Ensembl ID		ENSG00000102934	ENSG00000159261
Uniprot IDs		Q9Y342	O95500
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum PH-gated Chloride Channel Activity Protein Binding Regulation Of Behavior Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Structural Constituent Of Myelin Sheath Protein Insertion Into Plasma Membrane Myelination Axon Ensheathment Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane Regulation Of Transcytosis Membrane Raft Polarization Positive Regulation Of Protein Folding Peptide-O-fucosyltransferase Activity Protein Localization To Paranode Region Of Axon Compact Myelin Peptidase Activator Activity Involved In Apoptotic Process Protein O-linked Glycosylation Via Fucose Membrane Raft Distribution Granular Component Protein Localization To Axon Schmidt-Lanterman Incisure Membrane Raft Membrane Raft Localization Regulation Of Protein Folding Fucosylation Fucosyltransferase Activity Luteinization Leydig Cell Differentiation
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