PLLP and RNF122

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PLLP	RNF122
Description		plasmolipin	ring finger protein 122
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Plasma Membrane Membrane Apical Plasma Membrane Myelin Sheath Compact Myelin Membrane Raft	Cytoplasm Endoplasmic Reticulum Golgi Apparatus Membrane
	Molecular Function	Protein Binding Structural Constituent Of Myelin Sheath Identical Protein Binding	Protein Binding Zinc Ion Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Monoatomic Ion Transport Regulation Of Endocytosis Myelin Assembly Myelination Regulation Of Transcytosis	Negative Regulation Of Mitochondrial Membrane Potential Positive Regulation Of Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination
Pathways
Drugs
Diseases
GWAS		HDL cholesterol levels ( 32203549) Hip circumference adjusted for BMI ( 28552196) Sleep duration ( 23728906) Systemic lupus erythematosus ( 28714469)	Pulse pressure ( 30578418)
Interacting Genes		57 interacting genes: AQP6 BCL2L13 BIK CCR2 CD164L2 CLDN14 CLEC12B CLEC2D CRB3 CREB3 CYB5R3 CYSRT1 DRD2 EBP ELOVL4 ERGIC3 FAM174A FAM209A FKBP7 FNDC9 FRS3 GOLT1A GPR35 GPX8 GRN HOXA1 HTR2B KCNJ6 KRT34 KRTAP10-1 KRTAP9-2 LHFPL5 LMNA MC4R MFF MMP14 MS4A12 OPRL1 PACC1 PGRMC2 PTAFR RNF122 SAR1A SLC10A6 SLC35H1 STING1 SYPL2 TIGIT TMEM14B TMEM167B TMEM174 TMPPE TMPRSS2 TNFSF14 TRIM59 VMA21 ZDHHC15	12 interacting genes: AQP1 CDS2 CTSA GPR37L1 PLLP RIGI UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2L6 UBE2N
Entrez ID		51090	79845
HPRD ID		11854	11498
Ensembl ID		ENSG00000102934	ENSG00000133874
Uniprot IDs		Q9Y342	Q9H9V4
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum PH-gated Chloride Channel Activity Protein Binding Regulation Of Behavior Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Ubiquitin Conjugating Enzyme Activity Ubiquitin-protein Transferase Activity Protein Polyubiquitination Modification-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation ISG15 Transferase Activity Proteolysis Protein Monoubiquitination ISG15-protein Conjugation Post-translational Protein Modification Macromolecule Catabolic Process Transferase Activity Positive Regulation Of Protein Polyubiquitination ATP Binding Regulation Of Protein Polyubiquitination Protein Modification Process Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Nitric Oxide Transmembrane Transporter Activity Metanephric Proximal Convoluted Tubule Segment 2 Development Nucleotide Binding TORC1 Signaling Negative Regulation Of TORC1 Signaling Negative Regulation Of BMP Signaling Pathway Catabolic Process Protein Autoubiquitination Metanephric Glomerulus Vasculature Development Glycerol Transmembrane Transporter Activity Corticotropin Secretion Lumenal Side Of Lysosomal Membrane Antiviral Innate Immune Response Phosphatidate Cytidylyltransferase Activity Prosaposin Receptor Activity Regulation Of Transcytosis Protein Metabolic Process TOR Signaling Ubiquitin Protein Ligase Activity Negative Regulation Of TOR Signaling Positive Regulation Of Saliva Secretion Cellular Response To Mercury Ion Hydrogen Peroxide Channel Activity Potassium Ion Transmembrane Transporter Activity Negative Regulation Of Chaperone-mediated Autophagy Regulation Of TORC1 Signaling UBC13-MMS2 Complex Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
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