PLLP and TMPPE

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PLLP	TMPPE
Description		plasmolipin	transmembrane protein with metallophosphoesterase domain
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Plasma Membrane Membrane Apical Plasma Membrane Myelin Sheath Compact Myelin Membrane Raft	Membrane
	Molecular Function	Protein Binding Structural Constituent Of Myelin Sheath Identical Protein Binding	Protein Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Monoatomic Ion Transport Regulation Of Endocytosis Myelin Assembly Myelination Regulation Of Transcytosis
Pathways
Drugs
Diseases
GWAS		HDL cholesterol levels ( 32203549) Hip circumference adjusted for BMI ( 28552196) Sleep duration ( 23728906) Systemic lupus erythematosus ( 28714469)	Asthma ( 31619474 31959851) Asthma (childhood onset) ( 31036433)
Interacting Genes		57 interacting genes: AQP6 BCL2L13 BIK CCR2 CD164L2 CLDN14 CLEC12B CLEC2D CRB3 CREB3 CYB5R3 CYSRT1 DRD2 EBP ELOVL4 ERGIC3 FAM174A FAM209A FKBP7 FNDC9 FRS3 GOLT1A GPR35 GPX8 GRN HOXA1 HTR2B KCNJ6 KRT34 KRTAP10-1 KRTAP9-2 LHFPL5 LMNA MC4R MFF MMP14 MS4A12 OPRL1 PACC1 PGRMC2 PTAFR RNF122 SAR1A SLC10A6 SLC35H1 STING1 SYPL2 TIGIT TMEM14B TMEM167B TMEM174 TMPPE TMPRSS2 TNFSF14 TRIM59 VMA21 ZDHHC15	35 interacting genes: AGTRAP ASGR2 CD79A CLDND2 CLRN1 CNR2 CYB561 FIS1 FXYD6 FXYD6-FXYD2 GPR152 IER3IP1 KCNJ6 KLRC1 LEMD1 MS4A1 PLLP PLPPR1 PNLIPRP1 REEP6 RETREG3 RTP2 SCN3B SFXN5 SLAMF6 SLC38A1 SMAGP SSMEM1 STX3 STX8 TMEM60 TMIE TRARG1 VAMP3 YIPF1
Entrez ID		51090	643853
HPRD ID		11854	18951
Ensembl ID		ENSG00000102934	ENSG00000188167
Uniprot IDs		Q9Y342	Q6ZT21
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum PH-gated Chloride Channel Activity Protein Binding Regulation Of Behavior Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Membrane Plasma Membrane Organelle Membrane Fusion SNAP Receptor Activity Vesicle Fusion SNARE Complex Organelle Fusion Membrane Fusion Vesicle Docking Endoplasmic Reticulum Organization Organelle Localization By Membrane Tethering External Side Of Plasma Membrane Membrane Docking
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