PLLP and CLEC12B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PLLP	CLEC12B
Description		plasmolipin	C-type lectin domain family 12 member B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Plasma Membrane Membrane Apical Plasma Membrane Myelin Sheath Compact Myelin Membrane Raft	Plasma Membrane External Side Of Plasma Membrane Membrane Protein-containing Complex
	Molecular Function	Protein Binding Structural Constituent Of Myelin Sheath Identical Protein Binding	Protein Binding Protein Phosphatase Binding Carbohydrate Binding Signaling Receptor Regulator Activity Signaling Receptor Inhibitor Activity
	Biological Process	Monoatomic Ion Transport Regulation Of Endocytosis Myelin Assembly Myelination Regulation Of Transcytosis	Natural Killer Cell Inhibitory Signaling Pathway Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Melanocyte Proliferation Negative Regulation Of Receptor Signaling Pathway Via STAT Negative Regulation Of Signaling Receptor Activity
Pathways
Drugs
Diseases
GWAS		HDL cholesterol levels ( 32203549) Hip circumference adjusted for BMI ( 28552196) Sleep duration ( 23728906) Systemic lupus erythematosus ( 28714469)	Malaria ( 31844061) Sensory disturbances after bilateral sagittal split ramus osteotomy ( 23834954) Systolic blood pressure in sickle cell anemia ( 24058526)
Interacting Genes		57 interacting genes: AQP6 BCL2L13 BIK CCR2 CD164L2 CLDN14 CLEC12B CLEC2D CRB3 CREB3 CYB5R3 CYSRT1 DRD2 EBP ELOVL4 ERGIC3 FAM174A FAM209A FKBP7 FNDC9 FRS3 GOLT1A GPR35 GPX8 GRN HOXA1 HTR2B KCNJ6 KRT34 KRTAP10-1 KRTAP9-2 LHFPL5 LMNA MC4R MFF MMP14 MS4A12 OPRL1 PACC1 PGRMC2 PTAFR RNF122 SAR1A SLC10A6 SLC35H1 STING1 SYPL2 TIGIT TMEM14B TMEM167B TMEM174 TMPPE TMPRSS2 TNFSF14 TRIM59 VMA21 ZDHHC15	11 interacting genes: IL1RL1 JAGN1 LPAR3 LSMEM2 MALL OPRM1 PLLP PMP22 SCD SEC22A VMA21
Entrez ID		51090	387837
HPRD ID		11854	18266
Ensembl ID		ENSG00000102934	ENSG00000256660
Uniprot IDs		Q9Y342	A0A140VK10 Q2HXU8
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum PH-gated Chloride Channel Activity Protein Binding Regulation Of Behavior Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Compact Myelin Myelination Axon Ensheathment Bleb Assembly Structural Constituent Of Myelin Sheath Membrane Myelin Assembly G-protein Alpha-subunit Binding G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Morphine Receptor Activity Negative Regulation Of Wnt Protein Secretion Beta-endorphin Receptor Activity Monounsaturated Fatty Acid Biosynthetic Process Interleukin-33 Binding Negative Regulation Of Protein Secretion Palmitoyl-CoA 9-desaturase Activity Interleukin-33 Receptor Activity Regulation Of Transcytosis Endoplasmic Reticulum Cellular Response To Morphine Stearoyl-CoA 9-desaturase Activity Regulation Of NMDA Receptor Activity Lysophosphatidic Acid Receptor Activity Negative Regulation Of Protein Transport Endoplasmic Reticulum Membrane Granulocyte Colony-stimulating Factor Signaling Pathway Vacuolar Proton-transporting V-type ATPase Complex Assembly Negative Regulation Of Establishment Of Protein Localization Oxidoreductase Activity, Acting On Paired Donors, With Oxidation Of A Pair Of Donors Resulting In The Reduction Of Molecular Oxygen To Two Molecules Of Water Interleukin-1 Receptor Activity Myeloid Leukocyte Differentiation Negative Regulation Of Secretion By Cell
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