EMP3 and RMDN3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		EMP3	RMDN3
Description		epithelial membrane protein 3 (MAM blood group)	regulator of microtubule dynamics 3
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Spindle Pole Nucleus Cytoplasm Mitochondrion Mitochondrial Outer Membrane Spindle Cytoskeleton Microtubule Spindle Microtubule Membrane Organelle Membrane Contact Site Intercellular Bridge Mitotic Spindle Pole Presynapse Postsynapse Glutamatergic Synapse
	Molecular Function	Protein Binding	Protein Binding Microtubule Binding
	Biological Process	Apoptotic Process Bleb Assembly	Intracellular Calcium Ion Homeostasis Apoptotic Process Cell Differentiation
Pathways
Drugs
Diseases
GWAS			Anxiety and stress-related disorders ( 31116379) Malaria ( 31844061) Refractive error ( 32231278)
Interacting Genes		43 interacting genes: AQP6 CD79A CLDN2 CLDN7 CREB3L1 CREM EDA ELOVL7 ERGIC3 FAM210B FNDC9 GJA5 GJB1 GPA33 GPR61 IFNGR2 IL3RA KIR3DL3 KLRC1 LDLRAD1 LEUTX LHFPL5 LRRC4C LYVE1 MR1 MS4A3 MUC1 OPRM1 P2RX7 PLEKHB2 RMDN3 SAR1A SECTM1 SIGLECL1 SLAMF8 SLC30A2 SLC35H1 SMIM3 SPACA1 TM4SF18 TMX2 TSPAN12 VSIG1	26 interacting genes: CYB561D2 EGFL8 EMP3 FAM3C GIMAP1 LHFPL5 NRM PELI2 PLP1 PSEN1 SLC13A3 SLC30A8 STX2 STX3 TF TFRC TMEM100 TMEM140 TMEM147 TMEM203 TMEM243 VAMP3 VAPA VKORC1 YWHAB YWHAG
Entrez ID		2014	55177
HPRD ID		18514	07687
Ensembl ID		ENSG00000142227	ENSG00000137824
Uniprot IDs		P54852	Q96TC7
PDB IDs			7CC7
Enriched GO Terms of Interacting Partners?		Membrane Protein Binding Plasma Membrane Gap Junction Assembly Regulation Of T Cell Mediated Immunity Regulation Of T Cell Mediated Cytotoxicity Cell-cell Junction Assembly	Membrane Organelle Localization By Membrane Tethering Membrane Docking SNAP Receptor Activity SNARE Complex Establishment Of Protein Localization Myeloid Leukocyte Differentiation HFE-transferrin Receptor Complex Membrane Fusion Vesicle Docking Intracellular Protein Localization Clathrin-coated Endocytic Vesicle Membrane Vesicle Positive Regulation Of Receptor Recycling Cytoplasmic Vesicle Intracellular Monoatomic Cation Homeostasis Intracellular Monoatomic Ion Homeostasis Inorganic Ion Homeostasis Vacuole Vesicle Fusion Organelle Membrane Fusion Myeloid Cell Differentiation Melanosome Secretory Granule Perinuclear Region Of Cytoplasm Regulation Of Receptor Recycling Nuclear Membrane Monoatomic Cation Homeostasis Monoatomic Ion Homeostasis Endoplasmic Reticulum Membrane Multicellular Organismal-level Iron Ion Homeostasis Positive Regulation Of Signaling Positive Regulation Of Coagulation Organelle Fusion Intracellular Chemical Homeostasis Response To Iron Ion Vesicle Organization Recycling Endosome Early Endosome Endoplasmic Reticulum Amide Transport Negative Regulation Of Core Promoter Binding High-affinity Sodium:dicarboxylate Symporter Activity Vitamin-K-epoxide Reductase (warfarin-insensitive) Activity Chemical Homeostasis Plasma Membrane Bounded Cell Projection Organization Regulation Of Protein Localization To Nucleus Metal Ion Transport Protein Binding Protein Sequestering Activity
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