RMDN3 and CYB561D2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RMDN3	CYB561D2
Description		regulator of microtubule dynamics 3	cytochrome b561 family member D2
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Nucleus Cytoplasm Mitochondrion Mitochondrial Outer Membrane Spindle Cytoskeleton Microtubule Spindle Microtubule Membrane Organelle Membrane Contact Site Intercellular Bridge Mitotic Spindle Pole Presynapse Postsynapse Glutamatergic Synapse	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Vesicle
	Molecular Function	Protein Binding Microtubule Binding	Protein Binding Oxidoreductase Activity Heme Binding Metal Ion Binding Transmembrane Ascorbate Ferrireductase Activity Transmembrane Monodehydroascorbate Reductase Activity
	Biological Process	Intracellular Calcium Ion Homeostasis Apoptotic Process Cell Differentiation	Transmembrane Transport Ascorbate Homeostasis
Pathways
Drugs
Diseases
GWAS		Anxiety and stress-related disorders ( 31116379) Malaria ( 31844061) Refractive error ( 32231278)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Depressive symptom (appetite changes) (binary trait) ( 31530331) Depressive symptoms (binary sum-score) ( 31530331) Depressive symptoms (sum-score) ( 31530331) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		26 interacting genes: CYB561D2 EGFL8 EMP3 FAM3C GIMAP1 LHFPL5 NRM PELI2 PLP1 PSEN1 SLC13A3 SLC30A8 STX2 STX3 TF TFRC TMEM100 TMEM140 TMEM147 TMEM203 TMEM243 VAMP3 VAPA VKORC1 YWHAB YWHAG	26 interacting genes: APP ARL13B BIK CD79A CLDN7 CLEC14A CLNK COQ9 CREB3L1 CYB5R3 ERGIC3 FAM209A FKBP7 GPX8 LMNA PDE4A PGRMC2 PSCA PTPN5 RMDN3 SLC18A1 SLC30A2 TIMMDC1 TMEM154 TMEM45B UNC119
Entrez ID		55177	11068
HPRD ID		07687	06143
Ensembl ID		ENSG00000137824	ENSG00000114395
Uniprot IDs		Q96TC7	O14569
PDB IDs		7CC7
Enriched GO Terms of Interacting Partners?		Membrane Organelle Localization By Membrane Tethering Membrane Docking SNAP Receptor Activity SNARE Complex Establishment Of Protein Localization Myeloid Leukocyte Differentiation HFE-transferrin Receptor Complex Membrane Fusion Vesicle Docking Intracellular Protein Localization Clathrin-coated Endocytic Vesicle Membrane Vesicle Positive Regulation Of Receptor Recycling Cytoplasmic Vesicle Intracellular Monoatomic Cation Homeostasis Intracellular Monoatomic Ion Homeostasis Inorganic Ion Homeostasis Vacuole Vesicle Fusion Organelle Membrane Fusion Myeloid Cell Differentiation Melanosome Secretory Granule Perinuclear Region Of Cytoplasm Regulation Of Receptor Recycling Nuclear Membrane Monoatomic Cation Homeostasis Monoatomic Ion Homeostasis Endoplasmic Reticulum Membrane Multicellular Organismal-level Iron Ion Homeostasis Positive Regulation Of Signaling Positive Regulation Of Coagulation Organelle Fusion Intracellular Chemical Homeostasis Response To Iron Ion Vesicle Organization Recycling Endosome Early Endosome Endoplasmic Reticulum Amide Transport Negative Regulation Of Core Promoter Binding High-affinity Sodium:dicarboxylate Symporter Activity Vitamin-K-epoxide Reductase (warfarin-insensitive) Activity Chemical Homeostasis Plasma Membrane Bounded Cell Projection Organization Regulation Of Protein Localization To Nucleus Metal Ion Transport Protein Binding Protein Sequestering Activity	Membrane
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