RMDN3 and EGFL8

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		RMDN3	EGFL8
Description		regulator of microtubule dynamics 3	EGF like domain multiple 8
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Nucleus Cytoplasm Mitochondrion Mitochondrial Outer Membrane Spindle Cytoskeleton Microtubule Spindle Microtubule Membrane Organelle Membrane Contact Site Intercellular Bridge Mitotic Spindle Pole Presynapse Postsynapse Glutamatergic Synapse	Extracellular Region Cell Surface
	Molecular Function	Protein Binding Microtubule Binding	Signaling Receptor Binding Calcium Ion Binding Protein Binding
	Biological Process	Intracellular Calcium Ion Homeostasis Apoptotic Process Cell Differentiation	Vasculogenesis In Utero Embryonic Development
Pathways
Drugs
Diseases
GWAS		Anxiety and stress-related disorders ( 31116379) Malaria ( 31844061) Refractive error ( 32231278)	Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Idiopathic membranous nephropathy ( 21323541) Inflammatory bowel disease ( 28067908) Oleic acid (18:1n-9) levels ( 23362303) Prostate cancer ( 23535732) Risk-taking tendency (4-domain principal component model) ( 30643258) Ulcerative colitis ( 28067908)
Interacting Genes		26 interacting genes: CYB561D2 EGFL8 EMP3 FAM3C GIMAP1 LHFPL5 NRM PELI2 PLP1 PSEN1 SLC13A3 SLC30A8 STX2 STX3 TF TFRC TMEM100 TMEM140 TMEM147 TMEM203 TMEM243 VAMP3 VAPA VKORC1 YWHAB YWHAG	3 interacting genes: KRTAP10-3 RMDN3 TIMM8B
Entrez ID		55177	80864
HPRD ID		07687	16854
Ensembl ID		ENSG00000137824	ENSG00000241404
Uniprot IDs		Q96TC7	A0A1U9X7N9 Q99944
PDB IDs		7CC7
Enriched GO Terms of Interacting Partners?		Membrane Organelle Localization By Membrane Tethering Membrane Docking SNAP Receptor Activity SNARE Complex Establishment Of Protein Localization Myeloid Leukocyte Differentiation HFE-transferrin Receptor Complex Membrane Fusion Vesicle Docking Intracellular Protein Localization Clathrin-coated Endocytic Vesicle Membrane Vesicle Positive Regulation Of Receptor Recycling Cytoplasmic Vesicle Intracellular Monoatomic Cation Homeostasis Intracellular Monoatomic Ion Homeostasis Inorganic Ion Homeostasis Vacuole Vesicle Fusion Organelle Membrane Fusion Myeloid Cell Differentiation Melanosome Secretory Granule Perinuclear Region Of Cytoplasm Regulation Of Receptor Recycling Nuclear Membrane Monoatomic Cation Homeostasis Monoatomic Ion Homeostasis Endoplasmic Reticulum Membrane Multicellular Organismal-level Iron Ion Homeostasis Positive Regulation Of Signaling Positive Regulation Of Coagulation Organelle Fusion Intracellular Chemical Homeostasis Response To Iron Ion Vesicle Organization Recycling Endosome Early Endosome Endoplasmic Reticulum Amide Transport Negative Regulation Of Core Promoter Binding High-affinity Sodium:dicarboxylate Symporter Activity Vitamin-K-epoxide Reductase (warfarin-insensitive) Activity Chemical Homeostasis Plasma Membrane Bounded Cell Projection Organization Regulation Of Protein Localization To Nucleus Metal Ion Transport Protein Binding Protein Sequestering Activity
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