EMP3 and SLAMF8

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		EMP3	SLAMF8
Description		epithelial membrane protein 3 (MAM blood group)	SLAM family member 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Cell Surface Membrane
	Molecular Function	Protein Binding	Protein Binding Signaling Receptor Activity Identical Protein Binding
	Biological Process	Apoptotic Process Bleb Assembly	Leukocyte Chemotaxis Involved In Inflammatory Response B-1 B Cell Lineage Commitment Immune Response Negative Regulation Of Macrophage Chemotaxis Defense Response To Bacterium Regulation Of B Cell Differentiation Negative Regulation Of Respiratory Burst Involved In Inflammatory Response Negative Regulation Of Monocyte Chemotaxis Phagosome Acidification Negative Regulation Of Neutrophil Migration Negative Regulation Of Dendritic Cell Chemotaxis
Pathways
Drugs
Diseases
GWAS			Crohn's disease ( 28067908)
Interacting Genes		43 interacting genes: AQP6 CD79A CLDN2 CLDN7 CREB3L1 CREM EDA ELOVL7 ERGIC3 FAM210B FNDC9 GJA5 GJB1 GPA33 GPR61 IFNGR2 IL3RA KIR3DL3 KLRC1 LDLRAD1 LEUTX LHFPL5 LRRC4C LYVE1 MR1 MS4A3 MUC1 OPRM1 P2RX7 PLEKHB2 RMDN3 SAR1A SECTM1 SIGLECL1 SLAMF8 SLC30A2 SLC35H1 SMIM3 SPACA1 TM4SF18 TMX2 TSPAN12 VSIG1	2 interacting genes: EMP3 NINJ2
Entrez ID		2014	56833
HPRD ID		18514	09429
Ensembl ID		ENSG00000142227	ENSG00000158714
Uniprot IDs		P54852	Q9P0V8
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Protein Binding Plasma Membrane Gap Junction Assembly Regulation Of T Cell Mediated Immunity Regulation Of T Cell Mediated Cytotoxicity Cell-cell Junction Assembly	Bleb Assembly Neuron Cell-cell Adhesion Cytolysis Membrane Destabilizing Activity Cholesterol Binding Tissue Regeneration
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