MLKL and NDUFB7

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		MLKL	NDUFB7
Gene Name		mixed lineage kinase domain-like	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I Mitochondrial Intermembrane Space
	Molecular Function	Protein Kinase Activity Protein Binding ATP Binding Protein Kinase Binding Protein Complex Binding	NADH Dehydrogenase (ubiquinone) Activity
	Biological Process	Protein Phosphorylation Protein Homotrimerization Necroptotic Process	Mitochondrial Electron Transport, NADH To Ubiquinone Respiratory Electron Transport Chain Cellular Metabolic Process Small Molecule Metabolic Process
Pathways			Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. Respiratory electron transport The citric acid (TCA) cycle and respiratory electron transport
Drugs			NADH
Diseases
GWAS		Testicular germ cell tumor ( 23666239)
Protein-Protein Interactions		5 interactors: ANAPC11 CDK1 NDUFB7 RAD18 THOC3	4 interactors: CAPN1 CKAP4 MAK MLKL
Entrez ID		197259	4713
HPRD ID		08752	11957
Ensembl ID		ENSG00000168404	ENSG00000099795
Uniprot IDs		Q8NB16	P17568
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Pronuclear Fusion Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Mitotic Cell Cycle Checkpoint Regulation Of Protein Ubiquitination Positive Regulation Of Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Cell Cycle Checkpoint Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Schwann Cell Differentiation Positive Regulation Of Proteolysis Viral MRNA Export From Host Cell Nucleus Mitotic Nuclear Division Protein Localization To Kinetochore Protein Localization To Chromosome, Centromeric Region Positive Regulation Of Protein Import Into Nucleus, Translocation Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Cell Division Negative Regulation Of Cell Cycle Regulation Of Protein Import Into Nucleus, Translocation Mitotic G2 DNA Damage Checkpoint Ventricular Cardiac Muscle Cell Development Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Negative Regulation Of DNA Recombination Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Response To Copper Ion Protein K11-linked Ubiquitination Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Transferase Activity Cellular Protein Catabolic Process Protein Ubiquitination Intracellular Transport Of Virus Nucleobase-containing Compound Metabolic Process DNA Repair Ventricular Cardiac Muscle Cell Differentiation Protein Localization To Chromosome Protein Modification By Small Protein Conjugation Positive Regulation Of Cardiac Muscle Cell Proliferation
Tagcloud ?		allowed autocrine back deficient endoplasmic er instead interacting intrinsic kills l929 lineage lymphotoxin necroptosis necrosis opportunities pathologies protect remarkably repression rescue reticulum ripk1 ripk3 stress stressors switch tnfr1 unresolved
Tagcloud (Difference) ?		allowed autocrine back deficient endoplasmic er instead interacting intrinsic kills l929 lineage lymphotoxin necroptosis necrosis opportunities pathologies protect remarkably repression rescue reticulum ripk1 ripk3 stress stressors switch tnfr1 unresolved
Tagcloud (Intersection) ?