EHHADH and CBS

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		EHHADH	CBS
Gene Name		enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase	cystathionine-beta-synthase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Peroxisome Cytosol	Nucleus Nucleolus Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	3-hydroxyacyl-CoA Dehydrogenase Activity Dodecenoyl-CoA Delta-isomerase Activity Enoyl-CoA Hydratase Activity Receptor Binding Enzyme Binding Coenzyme Binding	Cystathionine Beta-synthase Activity Protein Binding Enzyme Binding Heme Binding Pyridoxal Phosphate Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Protein Homodimerization Activity Metal Ion Binding Modified Amino Acid Binding
	Biological Process	Internal Protein Amino Acid Acetylation Fatty Acid Beta-oxidation	Sulfur Amino Acid Metabolic Process Cysteine Biosynthetic Process From Serine L-serine Metabolic Process L-serine Catabolic Process Cysteine Biosynthetic Process Via Cystathionine Transsulfuration L-cysteine Catabolic Process Cellular Nitrogen Compound Metabolic Process Homocysteine Catabolic Process Small Molecule Metabolic Process Homocysteine Metabolic Process Hydrogen Sulfide Biosynthetic Process
Pathways			Sulfur amino acid metabolism Metabolism of amino acids and derivatives Cysteine formation from homocysteine
Drugs		NADH	Pyridoxal Phosphate S-Adenosylmethionine L-Serine L-Cysteine Heme
Diseases
GWAS		Cognitive performance ( 19734545) Major depressive disorder ( 21042317)	Blood trace element (Se levels) ( 23720494) Homocysteine levels ( 20031578) Obesity-related traits ( 23251661)
Protein-Protein Interactions		27 interactors: ACTB ACTG1 BHLHE40 CAT CBS CCDC102B DES FUNDC1 KCTD6 KCTD9 KRTAP10-7 LZTS2 MID1 NECAB2 PNMA1 SCP2 SSNA1 SSX2IP TNIP1 TPP2 TRAF1 TRIM27 TRIM41 TRIM54 TRIM55 TRIM63 ZBTB9	20 interactors: CBX4 COL4A3BP DAXX EHHADH FXR2 HGS HID1 HTT PIAS1 PIAS3 PIN1 PRKAG1 PRKAR1A PSMA1 RANBP9 UBASH3A UBE2I UGP2 VTA1 ZDHHC17
Entrez ID		1962	875
HPRD ID		06125	01994
Ensembl ID		ENSG00000113790	ENSG00000160200
Uniprot IDs		Q08426 Q9NY65	P35520 Q9NTF0
PDB IDs			1JBQ 1M54 4L0D 4L27 4L28 4L3V
Enriched GO Terms of Interacting Partners?		Cellular Component Assembly Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Complex Assembly Organelle Organization Negative Regulation Of Microtubule Depolymerization Intraciliary Transport Cytoskeleton Organization Purine Nucleotide Catabolic Process Platelet Aggregation Protein Oligomerization Microtubule-based Process Negative Regulation Of Microtubule Polymerization Or Depolymerization Cysteine Biosynthetic Process From Serine Lipid Hydroperoxide Transport Positive Regulation Of Intracellular Cholesterol Transport Homocysteine Catabolic Process Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Cysteine Biosynthetic Process Via Cystathionine Response To Stimulus Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Serine Family Amino Acid Metabolic Process Defense Response Retina Homeostasis Protein Homooligomerization Signal Transduction Regulation Of Intracellular Cholesterol Transport Negative Regulation Of Interleukin-2 Secretion Transsulfuration Protein Ubiquitination Regulation Of Microtubule Polymerization Or Depolymerization Negative Regulation Of Viral Process Nucleotide Catabolic Process Protein Modification By Small Protein Conjugation Depurination Cysteine Biosynthetic Process L-cysteine Catabolic Process Hydrogen Sulfide Biosynthetic Process Adherens Junction Organization Signaling Immune System Process L-serine Catabolic Process Inositol Trisphosphate Biosynthetic Process Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Response To Stress Negative Regulation Of Protein Complex Disassembly Ephrin Receptor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Cell Communication Cellular Response To Stimulus Ciliary Receptor Clustering Involved In Smoothened Signaling Pathway	Protein Sumoylation Positive Regulation Of Transferase Activity Positive Regulation Of Protein Modification Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Peptidyl-lysine Modification Positive Regulation Of Protein Sumoylation Regulation Of Signaling Cell Cycle Cellular Protein Modification Process Regulation Of Cellular Protein Metabolic Process Protein Modification By Small Protein Conjugation Regulation Of Protein Sumoylation Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Signal Transduction Androgen Receptor Signaling Pathway Regulation Of Protein Ubiquitination Endosomal Transport Endoplasmic Reticulum Organization Protein Transport Regulation Of Cell Cycle Peptidyl-amino Acid Modification Neural Plate Formation Response To Brefeldin A Positive Regulation Of SUMO Transferase Activity Establishment Of Protein Localization Viral Process Monocarboxylic Acid Metabolic Process Intracellular Transport Response To Stimulus Cellular Protein Metabolic Process Positive Regulation Of Catalytic Activity Cell Cycle Process Negative Regulation Of Signal Transduction Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Ubiquitin-protein Transferase Activity ER To Golgi Ceramide Transport Serotonin Uptake Lactate Biosynthetic Process From Pyruvate Positive Regulation Of Ligase Activity Small Molecule Metabolic Process Mitotic Cell Cycle Process Mesoderm Formation Regulation Of Catalytic Activity Negative Regulation Of Signaling Mesoderm Morphogenesis Organelle Organization Regulation Of Ubiquitin-protein Transferase Activity
Tagcloud ?		1n9c acsl3 agpat3 bovinesnp50 bta1 c10 c12 c14 c18 chuk dgat1 echs1 groundwork htr1b lipj lipk minpp1 mogat1 nfkb2 osbpl8 oxct1 plink prkg1 scd1 sfa sorbs1 ufa underling unraveling	catalyze cerevisiae considerably consumed dehydrogenase fermentation flux insufficient lacks metabolically mixtures oxygenation pentose pichia reductase s103 s104 saccharomyces stipitis tal tal1 tkl1 transaldolase transketolase utilization xyl1 xyl2 xylitol xylose
Tagcloud (Difference) ?		1n9c acsl3 agpat3 bovinesnp50 bta1 c10 c12 c14 c18 chuk dgat1 echs1 groundwork htr1b lipj lipk minpp1 mogat1 nfkb2 osbpl8 oxct1 plink prkg1 scd1 sfa sorbs1 ufa underling unraveling	catalyze cerevisiae considerably consumed dehydrogenase fermentation flux insufficient lacks metabolically mixtures oxygenation pentose pichia reductase s103 s104 saccharomyces stipitis tal tal1 tkl1 transaldolase transketolase utilization xyl1 xyl2 xylitol xylose
Tagcloud (Intersection) ?