AHR and NR2F1

Number of citations of the paper that reports this interaction (PMID 10620335)
30

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		AHR	NR2F1
Gene Name		aryl hydrocarbon receptor	nuclear receptor subfamily 2, group F, member 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm Cytosolic Aryl Hydrocarbon Receptor Complex Nuclear Aryl Hydrocarbon Receptor Complex	Nucleus Nucleoplasm
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Signal Transducer Activity Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Protein Binding Transcription Factor Binding Enhancer Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity Protein Dimerization Activity Hsp90 Protein Binding E-box Binding	Sequence-specific DNA Binding Transcription Factor Activity Steroid Hormone Receptor Activity Transcription Coactivator Activity Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Retinoic Acid-responsive Element Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Blood Vessel Development Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Xenobiotic Metabolic Process Apoptotic Process Cell Cycle Response To Xenobiotic Stimulus Response To Toxic Substance Regulation Of Gene Expression Intracellular Receptor Signaling Pathway Prostate Gland Development Regulation Of B Cell Proliferation Circadian Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Positive Regulation Of Transcription From RNA Polymerase II Promoter	Negative Regulation Of Transcription From RNA Polymerase II Promoter Neuron Migration Transcription Initiation From RNA Polymerase II Promoter Signal Transduction Gene Expression Negative Regulation Of Neuron Projection Development Cerebral Cortex Regionalization Intracellular Receptor Signaling Pathway Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways			Generic Transcription Pathway Nuclear Receptor transcription pathway
Drugs
Diseases
GWAS		Caffeine consumption ( 21490707) Coffee consumption ( 21357676) Metabolic traits ( 21886157)
Protein-Protein Interactions		34 interactors: AIP AR ARNT ARNTL BRCA1 CCNT1 CUL4B DAP3 EP300 ESR1 GTF2F1 GTF2F2 HSP90AA1 IVNS1ABP NCOA1 NCOA2 NCOA7 NCOR2 NEDD8 NR2F1 NRIP1 PTGES3 RB1 RELA SMARCA4 SP1 SRC STUB1 TAF4 TAF6 TAF7 TAF9 TBP XPO1	21 interactors: AHR BCL11A BCL11B CBX5 COPS2 EEF1D ESR1 GRIP1 GTF2B HNF4A ISL1 MAP6 NCOA1 NCOA3 NCOR2 NSD1 PFDN1 PHB2 RXRA SP1 THRA
Entrez ID		196	7025
HPRD ID		02596	00584
Ensembl ID		ENSG00000106546	ENSG00000175745
Uniprot IDs		P35869	F1DAL7 F1DAL9 P10589
PDB IDs			2EBL
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process DNA-templated Transcription, Initiation Gene Expression Cellular Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Intracellular Receptor Signaling Pathway Positive Regulation Of Metabolic Process RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Viral Process Regulation Of Transcription, DNA-templated Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Nitrogen Compound Metabolic Process RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Gene Expression Regulation Of Metabolic Process Transcription Elongation From RNA Polymerase II Promoter Cellular Metabolic Process DNA-templated Transcription, Elongation Positive Regulation Of Viral Transcription Regulation Of Cellular Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Rhythmic Process Regulation Of Viral Transcription Positive Regulation Of Viral Process Negative Regulation Of Signal Transduction Transforming Growth Factor Beta Receptor Signaling Pathway Androgen Receptor Signaling Pathway Signal Transduction	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process RNA Biosynthetic Process Regulation Of RNA Metabolic Process Gland Development Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Intracellular Receptor Signaling Pathway RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Multicellular Organismal Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Anatomical Structure Development System Development DNA-templated Transcription, Initiation Organ Development Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Developmental Process Negative Regulation Of Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Reproductive Process Negative Regulation Of Biosynthetic Process Organ Morphogenesis Developmental Process Involved In Reproduction Response To Steroid Hormone Anatomical Structure Morphogenesis Negative Regulation Of Transcription From RNA Polymerase II Promoter Mammary Gland Development Cellular Response To Steroid Hormone Stimulus Cellular Response To Hormone Stimulus
Tagcloud ?		12f actions aryl biologically constant dioxin dissociation eadie elicited equilibrium exert exerts half hofstee hydrocarbon kd keratinocytes lost maximal modulating opposing pmol ra rars scc tcdbf tcdd tetrachlorodibenzo trans	advantageous appearing begins coincides comprise embryoid emerge hesc hescs hipsc hipscs irx2 lastly manifested nestin neural neuroectoderm nr2f2 oct4 otx2 pax6 pluripotency precedes primitive pyramidal rosette rosettes serotonergic sox1
Tagcloud (Difference) ?		12f actions aryl biologically constant dioxin dissociation eadie elicited equilibrium exert exerts half hofstee hydrocarbon kd keratinocytes lost maximal modulating opposing pmol ra rars scc tcdbf tcdd tetrachlorodibenzo trans	advantageous appearing begins coincides comprise embryoid emerge hesc hescs hipsc hipscs irx2 lastly manifested nestin neural neuroectoderm nr2f2 oct4 otx2 pax6 pluripotency precedes primitive pyramidal rosette rosettes serotonergic sox1
Tagcloud (Intersection) ?