NR2F1 and GTF2B

Number of citations of the paper that reports this interaction (PMID 1517211)
89

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		NR2F1	GTF2B
Gene Name		nuclear receptor subfamily 2, group F, member 1	general transcription factor IIB
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Nucleoplasm Nucleolus
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Steroid Hormone Receptor Activity Transcription Coactivator Activity Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Retinoic Acid-responsive Element Binding	Core Promoter Binding Protein Binding Transcription Factor Binding Zinc Ion Binding TBP-class Protein Binding Thyroid Hormone Receptor Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Neuron Migration Transcription Initiation From RNA Polymerase II Promoter Signal Transduction Gene Expression Negative Regulation Of Neuron Projection Development Cerebral Cortex Regionalization Intracellular Receptor Signaling Pathway Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process
Pathways		Generic Transcription Pathway Nuclear Receptor transcription pathway	RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription HIV Infection RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		21 interactors: AHR BCL11A BCL11B CBX5 COPS2 EEF1D ESR1 GRIP1 GTF2B HNF4A ISL1 MAP6 NCOA1 NCOA3 NCOR2 NSD1 PFDN1 PHB2 RXRA SP1 THRA	56 interactors: ATF4 BCL3 CIITA CREBBP CTBP1 DEPDC7 DHX9 DRAP1 EP300 ESR1 ESRRA FBXO25 FOXF2 GTF2E1 GTF2E2 GTF2F1 GTF2F2 GTF2H4 HMGCL HNF4A HSF1 IKZF1 JAK3 JUN KLF5 MCM2 MECP2 MYC NCOA1 NCOA3 NCOA4 NCOR1 NOLC1 NR1D2 NR2F1 NR5A1 POLR2A POLR2E POU3F2 PSMC2 PSMC5 REL RELA REST SLC22A2 SRA1 TAF11 TAF9 TBP TBPL1 TCEA2 THRA TNIP1 TRAM2 VDR YWHAE
Entrez ID		7025	2959
HPRD ID		00584	08928
Ensembl ID		ENSG00000175745	ENSG00000137947
Uniprot IDs		F1DAL7 F1DAL9 P10589	Q00403
PDB IDs		2EBL	1C9B 1DL6 1RLY 1RO4 1TFB 1VOL 2PHG
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process RNA Biosynthetic Process Regulation Of RNA Metabolic Process Gland Development Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Intracellular Receptor Signaling Pathway RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Multicellular Organismal Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Anatomical Structure Development System Development DNA-templated Transcription, Initiation Organ Development Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Developmental Process Negative Regulation Of Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Reproductive Process Negative Regulation Of Biosynthetic Process Organ Morphogenesis Developmental Process Involved In Reproduction Response To Steroid Hormone Anatomical Structure Morphogenesis Negative Regulation Of Transcription From RNA Polymerase II Promoter Mammary Gland Development Cellular Response To Steroid Hormone Stimulus Cellular Response To Hormone Stimulus	Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter RNA Metabolic Process Gene Expression DNA-templated Transcription, Initiation Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Biosynthetic Process Nucleobase-containing Compound Metabolic Process Regulation Of RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Regulation Of Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process DNA-templated Transcription, Elongation Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Transcription Elongation From RNA Polymerase II Promoter Viral Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Intracellular Receptor Signaling Pathway Regulation Of Viral Transcription Response To Organic Substance Positive Regulation Of Viral Transcription Regulation Of Viral Process Cellular Response To Organic Substance Positive Regulation Of Viral Process Metabolic Process Steroid Hormone Mediated Signaling Pathway
Tagcloud ?		advantageous appearing begins coincides comprise embryoid emerge hesc hescs hipsc hipscs irx2 lastly manifested nestin neural neuroectoderm nr2f2 oct4 otx2 pax6 pluripotency precedes primitive pyramidal rosette rosettes serotonergic sox1
Tagcloud (Difference) ?		advantageous appearing begins coincides comprise embryoid emerge hesc hescs hipsc hipscs irx2 lastly manifested nestin neural neuroectoderm nr2f2 oct4 otx2 pax6 pluripotency precedes primitive pyramidal rosette rosettes serotonergic sox1
Tagcloud (Intersection) ?