AHR and NRIP1

Number of citations of the paper that reports this interaction (PMID 10428779)
30

Data Source:
HPRD (in vivo, in vitro)

		AHR	NRIP1
Gene Name		aryl hydrocarbon receptor	nuclear receptor interacting protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm Cytosolic Aryl Hydrocarbon Receptor Complex Nuclear Aryl Hydrocarbon Receptor Complex	Histone Deacetylase Complex Nucleus Nucleoplasm Nucleolus Nuclear Speck Cell Junction
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Signal Transducer Activity Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Protein Binding Transcription Factor Binding Enhancer Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity Protein Dimerization Activity Hsp90 Protein Binding E-box Binding	Core Promoter Sequence-specific DNA Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Estrogen Receptor Binding Nuclear Hormone Receptor Binding Glucocorticoid Receptor Binding Histone Deacetylase Binding Retinoid X Receptor Binding Androgen Receptor Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Blood Vessel Development Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Xenobiotic Metabolic Process Apoptotic Process Cell Cycle Response To Xenobiotic Stimulus Response To Toxic Substance Regulation Of Gene Expression Intracellular Receptor Signaling Pathway Prostate Gland Development Regulation Of B Cell Proliferation Circadian Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Positive Regulation Of Transcription From RNA Polymerase II Promoter	Negative Regulation Of Transcription From RNA Polymerase II Promoter Ovarian Follicle Rupture Transcription, DNA-templated Circadian Rhythm Lipid Storage Androgen Receptor Signaling Pathway Circadian Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS		Caffeine consumption ( 21490707) Coffee consumption ( 21357676) Metabolic traits ( 21886157)	Breast cancer ( 23535729) Cognitive performance ( 19734545)
Protein-Protein Interactions		34 interactors: AIP AR ARNT ARNTL BRCA1 CCNT1 CUL4B DAP3 EP300 ESR1 GTF2F1 GTF2F2 HSP90AA1 IVNS1ABP NCOA1 NCOA2 NCOA7 NCOR2 NEDD8 NR2F1 NRIP1 PTGES3 RB1 RELA SMARCA4 SP1 SRC STUB1 TAF4 TAF6 TAF7 TAF9 TBP XPO1	53 interactors: ACTN2 AHR APP AR ARPC3 BRCA1 CCDC85B CDK8 CEP70 CIB1 CTBP1 CTBP2 DNMT1 DNMT3A DNMT3B E2F1 ESR1 ESR2 ESRRA ESRRB ESRRG HDAC1 HDAC2 HDAC3 HDAC5 HDAC9 HNF4A JUN KAT2B LDOC1 MAP3K7 NR0B1 NR1H2 NR1H3 NR2C1 NR3C1 NR5A1 NR5A2 PPARA PPARD PPARG PRMT1 RARA RORB RXRA RXRB TEX11 THRA THRB TNFRSF14 TRAF2 VDR YWHAH
Entrez ID		196	8204
HPRD ID		02596	03927
Ensembl ID		ENSG00000106546	ENSG00000180530
Uniprot IDs		P35869	A8K171 P48552
PDB IDs			2GPO 2GPP
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process DNA-templated Transcription, Initiation Gene Expression Cellular Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Intracellular Receptor Signaling Pathway Positive Regulation Of Metabolic Process RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Viral Process Regulation Of Transcription, DNA-templated Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Nitrogen Compound Metabolic Process RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Gene Expression Regulation Of Metabolic Process Transcription Elongation From RNA Polymerase II Promoter Cellular Metabolic Process DNA-templated Transcription, Elongation Positive Regulation Of Viral Transcription Regulation Of Cellular Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Rhythmic Process Regulation Of Viral Transcription Positive Regulation Of Viral Process Negative Regulation Of Signal Transduction Transforming Growth Factor Beta Receptor Signaling Pathway Androgen Receptor Signaling Pathway Signal Transduction	Steroid Hormone Mediated Signaling Pathway Intracellular Receptor Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Hormone-mediated Signaling Pathway DNA-templated Transcription, Initiation Cellular Response To Steroid Hormone Stimulus Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Organic Substance Cellular Response To Organic Cyclic Compound Cellular Response To Lipid Positive Regulation Of Gene Expression Cellular Response To Hormone Stimulus Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Response To Organic Substance Transcription From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Response To Steroid Hormone Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Response To Organic Cyclic Compound Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Response To Hormone Gene Expression Response To Lipid Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Positive Regulation Of Metabolic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Signal Transduction
Tagcloud ?		12f actions aryl biologically constant dioxin dissociation eadie elicited equilibrium exert exerts half hofstee hydrocarbon kd keratinocytes lost maximal modulating opposing pmol ra rars scc tcdbf tcdd tetrachlorodibenzo trans	accurately blastx classifications close cog degs density differentially downloaded enriched esr1 genecodis gotm gse7429 hundred includes language mapped mineral module modules obtain omnibus osteoprotegerin packages ppid searched software vdr
Tagcloud (Difference) ?		12f actions aryl biologically constant dioxin dissociation eadie elicited equilibrium exert exerts half hofstee hydrocarbon kd keratinocytes lost maximal modulating opposing pmol ra rars scc tcdbf tcdd tetrachlorodibenzo trans	accurately blastx classifications close cog degs density differentially downloaded enriched esr1 genecodis gotm gse7429 hundred includes language mapped mineral module modules obtain omnibus osteoprotegerin packages ppid searched software vdr
Tagcloud (Intersection) ?