AHR and TAF6

Number of citations of the paper that reports this interaction (PMID 15641800)
3

Data Source:
BioGRID (pull down)

		AHR	TAF6
Gene Name		aryl hydrocarbon receptor	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm Cytosolic Aryl Hydrocarbon Receptor Complex Nuclear Aryl Hydrocarbon Receptor Complex	Nucleus Nucleoplasm Transcription Factor TFIID Complex Cytoplasm Transcription Factor TFTC Complex MLL1 Complex
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Signal Transducer Activity Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Protein Binding Transcription Factor Binding Enhancer Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity Protein Dimerization Activity Hsp90 Protein Binding E-box Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein Heterodimerization Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Blood Vessel Development Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Xenobiotic Metabolic Process Apoptotic Process Cell Cycle Response To Xenobiotic Stimulus Response To Toxic Substance Regulation Of Gene Expression Intracellular Receptor Signaling Pathway Prostate Gland Development Regulation Of B Cell Proliferation Circadian Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Positive Regulation Of Transcription From RNA Polymerase II Promoter	DNA-templated Transcription, Initiation Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Cell Proliferation Gene Expression Viral Process Negative Regulation Of Cell Cycle Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Pathways			RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription HIV Infection RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome
Drugs
Diseases
GWAS		Caffeine consumption ( 21490707) Coffee consumption ( 21357676) Metabolic traits ( 21886157)
Protein-Protein Interactions		34 interactors: AIP AR ARNT ARNTL BRCA1 CCNT1 CUL4B DAP3 EP300 ESR1 GTF2F1 GTF2F2 HSP90AA1 IVNS1ABP NCOA1 NCOA2 NCOA7 NCOR2 NEDD8 NR2F1 NRIP1 PTGES3 RB1 RELA SMARCA4 SP1 SRC STUB1 TAF4 TAF6 TAF7 TAF9 TBP XPO1	24 interactors: AHR APP CIITA GTF2E1 HIST3H3 HNF4A NCOR1 NFYA NFYB NFYC NR1D2 RELA SH3KBP1 TAF1 TAF10 TAF11 TAF12 TAF2 TAF4 TAF5 TAF7 TAF8 TAF9 TAF9B
Entrez ID		196	6878
HPRD ID		02596	11807
Ensembl ID		ENSG00000106546	ENSG00000106290
Uniprot IDs		P35869	P49848
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process DNA-templated Transcription, Initiation Gene Expression Cellular Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Intracellular Receptor Signaling Pathway Positive Regulation Of Metabolic Process RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Viral Process Regulation Of Transcription, DNA-templated Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Nitrogen Compound Metabolic Process RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Gene Expression Regulation Of Metabolic Process Transcription Elongation From RNA Polymerase II Promoter Cellular Metabolic Process DNA-templated Transcription, Elongation Positive Regulation Of Viral Transcription Regulation Of Cellular Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Rhythmic Process Regulation Of Viral Transcription Positive Regulation Of Viral Process Negative Regulation Of Signal Transduction Transforming Growth Factor Beta Receptor Signaling Pathway Androgen Receptor Signaling Pathway Signal Transduction	Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Transcription Elongation From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Elongation Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Viral Process Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Intracellular Receptor Signaling Pathway Cellular Metabolic Process Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Regulation Of Cellular Process Peptidyl-lysine Modification Rhythmic Process Histone H3 Acetylation Chromatin Modification Metabolic Process Histone Modification Chromosome Organization Chromatin Organization Negative Regulation Of Transcription, DNA-templated
Tagcloud ?		12f actions aryl biologically constant dioxin dissociation eadie elicited equilibrium exert exerts half hofstee hydrocarbon kd keratinocytes lost maximal modulating opposing pmol ra rars scc tcdbf tcdd tetrachlorodibenzo trans	acting alternative choice cis comparative decisions define depletion dictate drives elements employ gain inducible microarray minigene modulate mutational nothing pivotal pol splice splicing taf6alpha taf6delta tfiid transcriptome triggering undefined
Tagcloud (Difference) ?		12f actions aryl biologically constant dioxin dissociation eadie elicited equilibrium exert exerts half hofstee hydrocarbon kd keratinocytes lost maximal modulating opposing pmol ra rars scc tcdbf tcdd tetrachlorodibenzo trans	acting alternative choice cis comparative decisions define depletion dictate drives elements employ gain inducible microarray minigene modulate mutational nothing pivotal pol splice splicing taf6alpha taf6delta tfiid transcriptome triggering undefined
Tagcloud (Intersection) ?